Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 731 clinical trials
European/International FMD Registry and Initiative (FEIRI)

The main objectives of FEIRI are: (i) To describe the demographic and arterial characteristics of FMD and related diseases at a global scale and according to countries and/or ethnic origin (ii) To evaluate the incidence and predictors of novel FMD lesions and complications (iii) To explore the commonalities and differences …

stenosis
  • 0 views
  • 16 May, 2022
  • 1 location
Effect of Ketosis on Pain and Quality of Life in Patients With Lipedema (Lipodiet)

Lipedema is a female progressive fat disorder, characterized by a symmetrical increase in subcutaneous adipose tissue in the lower extremities with the exception of the waist. The condition is often misdiagnosed and underdiagnosed. The etiology is poorly understood. Affects about 11% of all women and may lead to pain and …

  • 2 views
  • 09 Apr, 2022
  • 2 locations
Pegtibatinase as an Enzyme Therapy for Patients With Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (COMPOSE)

Homocystinuria caused by Cystathionine Beta-Synthase (CBS) Deficiency is a rare autosomal-recessive metabolic condition characterized by an excess of homocysteine (Hcy) in the plasma, tissues and urine. It is due to reduced or absent activity of the CBS enzyme, and is also known as classical homocystinuria. The symptoms associated with homocystinuria …

  • 55 views
  • 28 Jul, 2022
  • 7 locations
The Effects of Prophylactic Limited Palmar Fasciectomy on Surgical Outcomes and Scarring

Research is instrumental for improving medical care and the patient experience. Finding new surgical techniques can create better outcomes and minimize recovery time and complications for patients. Some patients undergoing trigger finger surgery with a pre-existing Dupuytren's cord may develop a thickened surgical scar after surgery, which can cause discomfort, …

fasciotomy
palmar fasciectomy
scarring
dupuytren's contracture
discomfort
  • 992 views
  • 24 Jul, 2022
  • 1 location
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema (Lipedema)

Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid. Little is known about the functional changes that lead to fat accumulation and pain in women with …

Accepts healthy volunteers
  • 331 views
  • 09 Apr, 2022
  • 1 location
Efficacy and Safety of Low-dose IL-2 in Patients With SLE: a Multicenter, Randomised, Placebo-controlled Trial

The management of active systemic lupus erythematosus (SLE) is challenging due to the heterogeneous nature of the disease and lack of specific treatment. Current treatment regimens mainly rely on corticosteroids and immunosuppressive agents which are associated with substantial adverse effects including various infections. Therefore, there is an unmet need for …

immunosuppressive agents
corticosteroids
lupus
hydroxychloroquine
cyclophosphamide
  • 117 views
  • 02 Mar, 2022
  • 1 location
Systemic Lupus Erythematosus Within the Framework of the Multidisciplinary Consultation (CO LUPUS)

Diagnosis and follow up of a lupus cohort in a multidisciplinary consultation in Brest ( France)

lupus
  • 0 views
  • 24 Mar, 2022
  • 1 location
O-GlcNAcylation Role in the Pathophysiology of Systemic Lupus Erythematosus (METABOLUPS)

This study aims at defining the role of O-GlcNAcylation is in the physiopathology of systemic lupus erythematosus (SLE). O-GlcNAcylation is a metabolic pathway potentially implicated in SLE with potential for the discovery of new therapeutic strategies.

lupus
  • 2 views
  • 24 Mar, 2022
Immune Mediators and Metabolites to Stratify Systemic Lupus Erythematosus Patients at High Risk of Cardio Vascular Diseases (ISLE)

Accelerated atherosclerosis is an established complication of systemic autoimmune diseases, particularly SLE. Young female patients with SLE are more likely to develop myocardial infarction than matched healthy controls, and CVD is nowadays one of the most common causes of death (27%) in lupus patients. While traditional CV risk factors cannot …

lupus
rheumatism
  • 0 views
  • 23 Jul, 2022
  • 2 locations
Study of Anti-Malarials in Incomplete Lupus Erythematosus

This project is a multicenter, randomized, placebo-controlled, double-blind clinical trial that is designed to test whether treating patients who are at risk for development of lupus with hydroxychloroquine can slow accumulation of disease features. Effects on clinical progression of symptoms, patient-reported outcomes and changes in the immune markers of response …

antimalarials
lupus
antinuclear antibody
hydroxychloroquine
arthritis
  • 118 views
  • 09 Nov, 2021
  • 7 locations