Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 732 clinical trials
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

endothelin
stress test
endothelin receptor antagonist
ralinepag
diuretics
  • 0 views
  • 22 Sep, 2021
  • 32 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

hypertension
endothelin
arginine
beta blockers
angiotensin ii
  • 5463 views
  • 24 Sep, 2021
  • 308 locations
Deployment o the Multidisciplinary Prospective Cohort Imminent

Immune-mediated inflammatory diseases (IMIDs) most often affect young patients and have high impact on morbidity and mortality with a significant alteration in the quality of life of patients with professional, social and emotional repercussions. Beyond this burden, IMIDs share many common pathophysiological mechanisms and treatments, known as "targeted therapies". Despite …

disease or disorder
  • 0 views
  • 24 May, 2021
  • 1 location
Improving Safety of Diagnosis and Therapy in the Inpatient Setting

To improve the safety of diagnosis and therapy for a set of conditions and undifferentiated symptoms for hospitalized patients, the investigators will employ a set of methods and tools from the disciplines of systems engineering, human factors, quality improvement,and data analytics to thoroughly analyze the problem, design and develop potential …

pneumonia
deep vein thrombosis
cough
thrombosis
deficiency
  • 87 views
  • 25 Jan, 2021
  • 1 location
European/International FMD Registry and Initiative

The main objectives of FEIRI are: (i) To describe the demographic and arterial characteristics of FMD and related diseases at a global scale and according to countries and/or ethnic origin (ii) To evaluate the incidence and predictors of novel FMD lesions and complications (iii) To explore the commonalities and differences …

  • 0 views
  • 28 Mar, 2021
  • 1 location
Telemonitoring of Treatment Effects in Connective Tissue Disease-associated Interstitial Lung Disease (TEL-CTD-ILD)

Impact of telemonitoring on quality of life (QoL) of patients with CTD-ILD Evaluation of health status of patients with connective tissue disease-associated interstitial lung

interstitial lung disease
oximetry
lung disease
remission
immunosuppressants
  • 0 views
  • 25 Jan, 2021
  • 1 location
Effect of Weight Loss on Body Composition and Metabolic Function in Women With Lipedema

Lipedema is a disorder characterized by massive, bilateral accumulation of fat below the waist and in the legs. Enlargement of the lower extremities is often accompanied by leg pain and accumulation of fluid. Little is known about the functional changes that lead to fat accumulation and pain in women with …

  • 151 views
  • 02 Apr, 2021
  • 1 location
Intermittent Pneumatic Compression in Women With Lipo-lymphedema (Lipedema With Swelling)

Lipedema is a connective tissue disorder that affects up to 10% of women. It is characterized by painful, swollen subcutaneous tissue and disproportionate fat accumulation (primarily in the

  • 14 views
  • 08 Apr, 2021
  • 1 location
Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease

Investigation of the effect of Low-intensity extracorporeal shockwave therapy (ESWT) for Peyronie's disease (PD) via a single blind, sham-controlled, randomized clinical trial. Investigators will not be blinded to group assignments, but penile curvature will be assessed from coded patient pictures by a blinded assessor.

  • 23 views
  • 02 May, 2021
  • 4 locations
Fractionated Carbon Dioxide Laser Therapy for Treatment of Peyronie's Disease

This is a pilot study that evaluates the use of Fractional Carbon Dioxide Laser Therapy in the treatment of Peyronie's Disease. Study participants will be assigned to receive Fractional Carbon Dioxide Laser Therapy at 10-15% laser density coverage.

  • 4 views
  • 15 May, 2021
  • 1 location