Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 88 clinical trials
A Study of Baricitinib in Participants With Rheumatoid Arthritis

This post-marketing study is designed to compare the safety of baricitinib versus tumor necrosis factor (TNF) inhibitors with respect to venous thromboembolic events (VTEs) when given to participants with rheumatoid arthritis (RA).

body mass index
tumor necrosis factor alpha
antirheumatics
baricitinib
tumour necrosis
  • 301 views
  • 12 Sep, 2021
  • 171 locations
Study To Assess Frequency Of Serious Infections In Clinical Practice In Japan For Adult Participants With Rheumatoid Arthritis Receiving Oral RINVOQ Tablets

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. RA can reduce the ability to perform everyday tasks. The purpose of this study is to observe the incidence of serious infections, regardless of their relationship to RINVOQ, in Japanese daily practice. RINVOQ …

stiffness
  • 0 views
  • 15 Sep, 2021
  • 24 locations
A Study of LY3462817 in Participants With Rheumatoid Arthritis

The reason for this study is to see if the study drug LY3462817 is safe and effective in participants with moderately to severely active rheumatoid arthritis (RA).

rheumatoid factor
biologic disease-modifying antirheumatic drug
antirheumatics
rheumatism
DMARD
  • 6 views
  • 12 Sep, 2021
  • 37 locations
Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis

The RESET-RA study will assess the safety and efficacy of the SetPoint System (study device) for the treatment of adult patients with active, moderate to severe rheumatoid arthritis who have had an inadequate response or intolerance to biologic or targeted synthetic Disease-Modifying Anti-Rheumatic Drugs (DMARDs). The study device contains a …

DMARD
antirheumatics
  • 0 views
  • 17 Sep, 2021
  • 24 locations
Prospective Observational Study of Filgotinib in Subjects With Rheumatoid Arthritis

An observational study to describe the effectiveness, safety, and patient-reported outcomes in patients with moderate to severe active rheumatoid arthritis (RA) receiving filgotinib in real-world setting.

  • 0 views
  • 18 Sep, 2021
  • 22 locations
Study to Evaluate Adverse Events and Change in Disease Activity in Participants Between 18 to 75 Years of Age Treated With Subcutaneous (SC) Injections of ABBV-154 for Moderately to Severely Active Rheumatoid Arthritis (RA)

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. This study evaluates how safe and effective ABBV-154 is in participants treated for moderately to severely active RA. Adverse events and change in the disease activity will be assessed. ABBV-154 is …

stiffness
rheumatism
methotrexate
antirheumatics
  • 11 views
  • 19 Sep, 2021
  • 315 locations
Smart Marker Annunciating Response to Rheumatologic Treatments SMART T

European recommendations indicate to start a conventional synthetic disease modifying antirheumatic drug (csDMARD) as soon as possible to reach the remission in early RA or low disease activity in established RA. If the target is not achieved with the first csDMARD and in presence of poor prognostic, addition of a …

methotrexate
remission
DMARD
antirheumatics
  • 0 views
  • 17 Sep, 2021
  • 15 locations
Uterine Filling Pressure in Hysteroscopy

The aim of the study is to compare the outcomes of patients undergoing hysteroscopy with a Myosure device with a pressure of 60 mmHg to those using the standard of 80 mmHg.

hysteroscopy
  • 7 views
  • 18 Sep, 2021
  • 1 location
A Study of Oral Upadacitinib Tablets to Assess Treatment Patterns Achievement of Treatment Targets and Maintenance of Response in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment …

stiffness
prednisone
glucocorticoids
remission
  • 7 views
  • 19 Sep, 2021
  • 234 locations
A Clinical Trial to Evaluate PCS499 in Treating Ulcerations in Patients Who Have Necrobiosis Lipoidica

This is a randomized, double blind, placebo controlled study that will evaluate the efficacy and safety of PCS499 as compared to placebo for the treatment of ulcerations of patients with necrobiosis lipoidica (NL) and will inform the design of future studies. Approximately 20 ulcerated NL patients who also meet other …

  • 0 views
  • 20 Sep, 2021
  • 5 locations