Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 83 clinical trials
A Pilot Study to Explore the Role of Gut Flora in Lupus

This study seeks to correlate microbiome sequencing data with information provided by patients and their medical records.

  • 22 views
  • 12 Sep, 2021
  • 1 location
A Study to Evaluate the Efficacy and Safety of BIIB059 in Adult Participants With Active Systemic Lupus Erythematosus Receiving Background Nonbiologic Lupus Standard of Care

The primary objective of this study is to demonstrate efficacy of BIIB059 compared with placebo in participants with active systemic lupus erythematosus (SLE), who are receiving background lupus standard of care (SOC) therapy in reducing disease activity. The secondary objectives of this study are to demonstrate early onset of efficacy …

antimalarials
rheumatism
  • 0 views
  • 12 Sep, 2021
  • 13 locations
Study of GS-5718 in Participants With Cutaneous Lupus Erythematosus (CLE)

The primary objective of this study is to evaluate the safety and tolerability of GS-5718 in participants with Cutaneous Lupus Erythematosus (CLE) with or without Systemic Lupus Erythematosus (SLE).

  • 0 views
  • 22 Sep, 2021
  • 1 location
Examination of Efficacy and Safety of Baricitinib in RA Patients

The aim of this study is to examine the efficacy and adverse events in the following 3 groups in rheumatoid arthritis patients: Baricitinib treatment for 12 months Biologics treatment for 12 months Tofacitinib treatment for 12 months

baricitinib
tofacitinib
  • 4 views
  • 23 Sep, 2021
  • 1 location
Single Arm Study Using the Symphony -- MRI Guided Focused Ultrasound System for the Treatment of Leiomyomas

Single arm, first-in human feasibility study using the Symphony - MRI guided focused ultrasound system for the treatment of leiomyomas. The study is expected to accrue over 12 months. This study will help determine the feasibility to ablate leiomyomas, as measured by MR thermometry and contrast enhanced imaging. In addition, …

MRI
hifu
leiomyoma
focused ultrasound
peri-menopausal
  • 260 views
  • 20 Sep, 2021
  • 1 location
Study To Assess Frequency Of Serious Infections In Clinical Practice In Japan For Adult Participants With Rheumatoid Arthritis Receiving Oral RINVOQ Tablets

Rheumatoid Arthritis (RA) is a chronic inflammatory disease causing pain, stiffness, swelling and loss of joint function. RA can reduce the ability to perform everyday tasks. The purpose of this study is to observe the incidence of serious infections, regardless of their relationship to RINVOQ, in Japanese daily practice. RINVOQ …

stiffness
  • 0 views
  • 22 Sep, 2021
  • 24 locations
Japan Post-Marketing Surveillance for Peficitinib to Assess Safety and Effectiveness in the Patients With Rheumatoid Arthritis

The objective of this study is to investigate the safety and effectiveness in routine clinical practice and actual clinical setting for all patients with rheumatoid arthritis (RA) treated with peficitinib.

  • 2 views
  • 22 Sep, 2021
  • 47 locations
A Study of Oral Upadacitinib Tablets to Assess Treatment Patterns Achievement of Treatment Targets and Maintenance of Response in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is an inflammatory disease of the joints causing pain, stiffness, swelling and loss of joint function. Despite the range of treatment options for RA steadily increasing, many patients remain sub-optimally managed, with sustained clinical remission rarely achieved. This study will assess the treatment patterns, achievement of treatment …

stiffness
remission
glucocorticoids
prednisone
  • 7 views
  • 22 Sep, 2021
  • 234 locations
Changes of Depression After First-year of Tofacitinib in RA Patients

12-month, single arm, prospective, non-interventional, multi-center study according to Czech legal definitions (Law 378/2007 Sb.).The primary objective of this study is to describe and evaluate the changes of depression level within 12 months from the start of tofacitinib therapy in patients with RA and at least minimal level of depression. …

depression
tofacitinib
  • 0 views
  • 22 Sep, 2021
  • 8 locations
Uterine Filling Pressure in Hysteroscopy

The aim of the study is to compare the outcomes of patients undergoing hysteroscopy with a Myosure device with a pressure of 60 mmHg to those using the standard of 80 mmHg.

hysteroscopy
  • 7 views
  • 18 Sep, 2021
  • 1 location