Connective Tissue Diseases Clinical Trials

A listing of Connective Tissue Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 692 clinical trials
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(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

(OSKIRA): A Phase III, Multi-centre, Randomised, Double-Blind, Placebo-Controlled, Parallel Group Study of Two Dosing Regimens of Investigational Product (Oral Agents) in Rheumatoid Arthritis Patients.

  • 148 views
  • 08 Nov, 2020
  • 1 location
A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (STELLAR)

The objectives of this study are to evaluate the efficacy and safety of sotatercept treatment (plus background PAH therapy) versus placebo (plus background PAH therapy) at 24 weeks in adults with PAH.

  • 0 views
  • 01 Aug, 2021
  • 38 locations
Effect of the Use of Specific Oral Hygiene Devices on Gingival Health Among Patients With Systemic Sclerosis

Systemic sclerosis is a rare multisystem connective-tissue disorder characterized by three major pathological hallmarks: widespread fibrosis, vasculopathy and immunological abnormalities. This

fibrosis
vascular disease
  • 0 views
  • 25 Jul, 2021
  • 1 location
Infections and Autoimmunity: Autobodies Screening in Multiple Sclerosis

connective tissue disorder [UCTD], Sjogren, antiphospholipid syndrome - APS, vasculitides, systemic lupus erythematosus [SLE], polymyositis, Hashimoto, multiple sclerosis, primary biliary

  • 11 views
  • 07 Nov, 2020
  • 1 location
Platelet Gel in Systemic Sclerosis

- Systemic sclerosis (scleroderma; SSc) is a connective tissue disease characterized by a progressive fibrosis of the skin and visceral organs. - A diffuse cutaneous

progressive systemic sclerosis
scleroderma
transforming growth factor beta-1
growth factor
endothelin
  • 24 views
  • 07 Nov, 2020
  • 1 location
Sildenafil for the Prevention of Right Heart Failure Following LVAD Implantation

tissue disease. Sildenafil has not yet been approved by Health Canada for the treatment of pulmonary hypertension in heart failure. Sildenafil lowers blood pressure in the lungs and lessens the workload

  • 25 views
  • 08 May, 2021
  • 4 locations
The Role of Tofacitinib in Steroid Withdrawal in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a systemic chronic arthritis characterized by systemic inflammation, persistent synovitis and final joint destruction Inflammatory diseases can lead to decreased productivity and impaired health-related quality of life. As a chronic disease, rheumatoid Chronic arthritis needs long-term treatment. At the same time, RA can cause skin, eye, …

DMARD
tofacitinib
synovitis
antirheumatics
stiffness
  • 0 views
  • 22 Jun, 2021
  • 1 location
Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement

The purpose of this study is to verify effect and tolerability of imatinib on pulmonary and skin fibrosis in patients affected by systemic sclerosis.

progressive systemic sclerosis
scleroderma
alveolitis
pulmonary involvement
imatinib
  • 33 views
  • 07 Nov, 2020
  • 1 location
A Randomized Open-label LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome

To assess the efficacy of angiotensin II receptor blocker, Losartan, to prevent progressive dilation of aortic root in patients with Marfan syndrome.

  • 0 views
  • 07 Nov, 2020
The Occurrence of Single Nucleotide Polymorphism Among Women Who Experienced Obstetric Anal Sphincter Injury

Single-nucleotide polymorphisms (SNP's) in connective tissue components are associated with increased risk of pelvic organ prolapse (POP). The investigators expect to find a difference in SNP's frequency between women who had Obstetric anal sphincter injuries (OASIS) and in the healthy population. The fact that pelvic organ prolapse (POP) and OASIS …

  • 0 views
  • 16 Jul, 2021
  • 1 location