Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 272 clinical trials
TAEST16001 in the Treatment of Soft Tissue Sarcoma

This study is an open, single arm, dose increasing early clinical study, which is divided into two parts: "3 + 3" designed dose escalation study and extended group study. The purpose of this study is to evaluate the safety, tolerance, PK, PD characteristics, and preliminary efficacy of TAEST16001 immunotherapy in …

filgrastim
cancer chemotherapy
ny-eso-1
carboplatin
ifosfamide
  • 0 views
  • 25 Jan, 2021
  • 1 location
Establishment of a Prospective Clinical-biological Database

A Clinical and Biological Database will provide to the scientific community a collection of blood and tissues with clinical data to improve knowledge about cancer and help to develope new cancer treatments. This database is specific to Sarcoma

cancer
  • 0 views
  • 25 Jan, 2021
  • 1 location
APX005M and Doxorubicin in Advanced Sarcoma

This phase II clinical trial will evaluate the safety and efficacy of adding APX005M (a CD40 agonistic monoclonal antibody) to doxorubicin for the treatment of patients with advanced soft tissue sarcoma. The investigators believe that doxorubicin, which is currently the standard of care for most advanced sarcomas, could work better …

cancer chemotherapy
anthracyclines
systemic therapy
stromal tumor
kaposi's sarcoma
  • 0 views
  • 30 Apr, 2021
Gemcitabine and Docetaxel With Radiation in Adults With Soft Tissue Sarcoma of the Extremities

The purpose of this Phase 1 research study is to obtain data or information on the safety and effectiveness of the combination of gemcitabine, docetaxel with radiation.

soft tissue sarcoma
cancer chemotherapy
docetaxel
gemcitabine
  • 7 views
  • 25 Mar, 2021
  • 1 location
Registry of Sarcoma Patients Treated With Permanently Implantable LDR CivaSheet

This patient study will determine the safety and toxicity of a permanently implantable brachytherapy source - CivaSheet - which is designed to deliver a therapeutic dose of low dose rate (LDR) radiation with polymer encased Palladium-103. CivaSheet will be implanted in sarcoma patients with disease presenting in the retroperitoneum, abdomen, …

  • 0 views
  • 25 Jan, 2021
  • 1 location
Anlotinib Hydrochloride for Soft Tissue Sarcoma Patients.

Anlotinib is a multi-target receptor tyrosine kinase inhibitor. It can inhibit the angiogenesis related kinase, such as Vascular Endothelial Growth Factor Receptor (VEGFR), Fibroblast Growth Factor Receptor(FGFR), Platelet-Derived Growth Factor Receptor(PDGFR), and tumor cell proliferation related kinase c-Kit kinase. Anlotinib is an efficient second line therapeutic agent in treatment for …

metastatic soft tissue sarcoma
metastasis
synovial sarcoma
anthracyclines
platelet count
  • 0 views
  • 25 Mar, 2021
  • 1 location
AG-120 in People With IDH1 Mutant Chondrosarcoma

This study is being done to see whether AG-120 is an effective and safe treatment for people with advanced/metastatic or recurrent chondrosarcoma that has IDH1 mutation.

kidney function tests
cancer
neutrophil count
measurable disease
  • 5 views
  • 24 Mar, 2021
  • 3 locations
Circulating Tumor DNA in Soft Tissue Sarcoma

This research study will collect blood and tumor tissue samples from patients with soft tissue sarcoma to look at circulating tumor deoxyribonucleic acid (DNA). When tumor cells are damaged or die, DNA from the tumor cells are released into the blood stream as the cells break down. This is called …

liposarcoma
tumor cells
leiomyosarcoma
undifferentiated pleomorphic sarcoma
cancer
  • 3 views
  • 22 Apr, 2021
  • 1 location
Rehabilitation and Quality of Life Assessment for Soft Tissue Sarcoma Treated With Radiotherapy and Surgery

This is a pilot study with a feasibility lead-in evaluating the use of multimodal cancer rehabilitation in patients planning to undergo radiotherapy and surgical resection for extremity or superficial trunk soft tissue sarcoma (STS). At enrollment, patients will be assigned to either a pre-operative radiation or post-operative radiation cohort.

cancer
soft tissue sarcoma
sarcoma of the extremity
  • 0 views
  • 26 Jan, 2021
  • 1 location
A Study of Durvalumab in Combination With Doxorubicin for Advanced Soft Tissue Sarcoma

The yearly incidence of soft-tissue sarcomas (STS) in the USA is roughly 11,280 cases, and metastatic STS have a median overall survival of about 12 months. Sarcomas of the soft tissue are a heterogeneous group of malignant tumors of mesenchymal origin that originate in connective tissue. Local control with wide …

immunomodulators
cancer chemotherapy
metastasis
olaratumab
growth factor
  • 1 views
  • 26 Jan, 2021
  • 1 location