Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 217 clinical trials
A Study of the Drug I131-Omburtamab in People With Desmoplastic Small Round Cell Tumors and Other Solid Tumors in the Peritoneum

The purpose of this study is to test any good and bad effects of the study drug 131I-omburtamab. 131I-omburtamab could prevent the cancer from returning, or delay the cancer from getting worse, but it could also cause side effects. Researchers hope to learn more about how 131I-omburtamab works in the …

cancer chemotherapy
desmoplastic
cancer
tumor progression
  • 24 views
  • 14 Jun, 2022
  • 1 location
Pulmonary Resectable Metastases of Osteosarcoma With Apatinib and CHemotherapy (PROACH)

The aim of this study is to evaluate the efficacy and safety of Second-line chemotherapy combined with Apatinib for the patients with resectable pulmonary metastasis of osteosarcoma.

metastasis
pulmonary metastasis
cancer
docetaxel
treatment consisted of
  • 0 views
  • 16 May, 2022
  • 1 location
Three Versus Five Years of Adjuvant Imatinib as Treatment of Patients With Operable GIST

In this study, patients who have been diagnosed with gastrointestinal stromal tumor (GIST) and have been treated with adjuvant imatinib for 3 years after surgery will be randomly allocated in a 1:1 ratio to receive imatinib (Gleevec) for 2 more years (Arm A) or to stop imatinib (Arm B). The …

ct scan
KIT
gastrointestinal stromal tumor
stromal tumor
imatinib
  • 7 views
  • 23 Mar, 2022
  • 1 location
CINSARC Signature and Correlation With Hemotherapy Efficacy in Soft-tissue Sarcomas. A Biomarker Study. (NEOSarcomics)

This is a prospective observational biomarker study including patients with non-metastatic, soft-tissue sarcomas (STS) for whom neoadjuvant chemotherapy is considered as the best option by the multidisciplinary sarcoma team of one of the participating centers.

cancer chemotherapy
measurable disease
ifosfamide
doxorubicin
carcinoma
  • 23 views
  • 27 Jan, 2022
  • 7 locations
A Phase II Trial of Preoperative Proton Therapy in Soft-tissue Sarcomas of the Extremities and Body Wall

When treated with surgery alone, many soft-tissue sarcomas have a high chance of coming back. Radiation therapy is frequently used in addition to surgery to reduce the chances of the sarcoma coming back. However, radiation can have long-term side effects on the normal tissues surrounding the tumor, leading to problems …

metastasis
soft tissue sarcoma
  • 10 views
  • 12 Mar, 2022
  • 1 location
Circulating Tumor DNA in Soft Tissue Sarcoma

This research study will collect blood and tumor tissue samples from patients with soft tissue sarcoma to look at circulating tumor deoxyribonucleic acid (DNA). When tumor cells are damaged or die, DNA from the tumor cells are released into the blood stream as the cells break down. This is called …

soft tissue sarcoma
undifferentiated pleomorphic sarcoma
tumor cells
leiomyosarcoma
cancer
  • 3 views
  • 16 Feb, 2022
  • 1 location
Establishment of a Prospective Clinical-biological Database

A Clinical and Biological Database will provide to the scientific community a collection of blood and tissues with clinical data to improve knowledge about cancer and help to develope new cancer treatments. This database is specific to Sarcoma

cancer
  • 0 views
  • 14 Nov, 2021
  • 1 location
A Single-arm, Open, Phase II Study of Chidamide Combined With Toripalimab in Refractory and Advanced Soft-tissue Sarcoma

Soft tissue sarcoma is a relatively rare malignant tumor with an incidence of about 1-2/100,000. The best way to obtain evidence-based medical evidence is to participate in clinical trials with new drugs (especially targeted drugs and immunotherapy). Chidamide, an oral subtype-selective histone deacetylase inhibitor monotherapy was effective on the patients …

metastasis
malignant peripheral nerve sheath tumor
advanced soft tissue sarcoma
epithelioid sarcoma
angiosarcoma
  • 2 views
  • 12 Feb, 2022
  • 1 location
A Study of SHR-1210 Plus Apatinib in Patients With Soft Tissue Sarcoma

The main purpose of this study is to evaluate the efficacy of SHR-1210 plus Apatinib versus AMD plus IFO in participants with soft tissue sarcoma.

kidney function tests
metastatic soft tissue sarcoma
apatinib
cancer chemotherapy
measurable disease
  • 3 views
  • 13 Feb, 2022
TAEST16001 in the Treatment of Soft Tissue Sarcoma

This study is an open, single arm, dose increasing early clinical study, which is divided into two parts: "3 + 3" designed dose escalation study and extended group study. The purpose of this study is to evaluate the safety, tolerance, PK, PD characteristics, and preliminary efficacy of TAEST16001 immunotherapy in …

filgrastim
soft tissue sarcoma
cancer
ifosfamide
doxorubicin
  • 0 views
  • 24 Nov, 2021
  • 1 location