Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 268 clinical trials
A Study of the Drugs Prexasertib Irinotecan and Temozolomide in People With Desmoplastic Small Round Cell Tumor and Rhabdomyosarcoma

The purpose of this study is to test whether the study drug prexasertib is a safe and effective treatment for people with DSRCT or RMS when given in combination with the standard drugs irinotecan and temozolomide. The study will test different doses of prexasertib in combination with irinotecan and temozolomide …

measurable disease
metastasis
renal function
antibody therapy
cancer
  • 7 views
  • 15 May, 2021
  • 1 location
Study of the Safety and Efficacy of Humanized 3F8 Bispecific Antibody (Hu3F8-BsAb) in Patients With Relapsed/Refractory Neuroblastoma Osteosarcoma and Other Solid Tumor Cancers

The purpose of this study is to test the safety of a study drug called humanized 3F8 bispecific antibody (Hu3F8-BsAb).

medulloblastoma
humanized 3f8 bispecific antibody
hu3f8
refractory neuroblastoma
iobenguane
  • 3 views
  • 03 Jun, 2021
  • 1 location
Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma

Among skin malignancies, patients with malignant melanoma or angiosarcoma are treated with BNCT using CICS-1 and SPM-011 (borofalan (10B)). Through this trial, safety and appropriate treatment dose will be determined.

angiosarcoma
skin lesion
cancer
  • 0 views
  • 23 Jan, 2021
  • 1 location
Does Cediranib With Paclitaxel or Cediranib and Olaparib Treat Advanced Endometrial Cancer Better Than Paclitaxel?

The COPELIA trial is evaluating two new tablet medications in endometrial cancer for the first time. It will include 129 women aged 16 years or older with advanced endometrial cancer whose cancer has worsened after their initial chemotherapy treatment. Participants will be allocated at random to one of three groups: …

recurrent disease
recurrent endometrial cancer
ovarian cancer
metastasis
endometrial carcinoma
  • 30 views
  • 23 Jan, 2021
  • 11 locations
Lenvatinib and Eribulin in Advanced Soft Tissue Sarcoma

This study is designed to test the safety and efficacy of the combination of lenvatinib, a drug that can inhibit the growth of supplying vessels around the tumors, and eribulin, a chemotherapy drug that targets the cancer cell during mitosis, in inoperable or metastatic adipocytic sarcoma and leiomyosarcoma.

lenvatinib
soft tissue sarcoma
measurable disease
metastasis
liver metastasis
  • 15 views
  • 11 Mar, 2021
  • 2 locations
Olaparib With Ceralasertib in Recurrent Osteosarcoma

This study is being done in order to evaluate the effectiveness of using two drugs (olaparib and ceralasertib) to treat patients with osteosarcoma that has not responded to treatment or has come back after treatment The names of the study drugs involved in this study are: Olaparib Ceralasertib

  • 0 views
  • 27 Jan, 2021
  • 1 location
Trial of Ixazomib for Kaposi Sarcoma

This phase II trial studies how well ixazomib works in treating patients with Kaposi sarcoma. Ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

  • 0 views
  • 08 Apr, 2021
  • 2 locations
Propranolol in Angiosarcoma

This is a window opportunity study of propranolol in patients with angiosarcoma. The aim of this study is to prospectively evaluate the activity of propranolol in the clinical setting as monotherapy, where the neoadjuvant setting provides a good opportunity to rapidly evaluate both the clinical response and histological response, without …

  • 0 views
  • 26 Jan, 2021
  • 1 location
ZW25 in Women With Endometrial Cancers

This study is being done to test the drug ZW25 and look at whether this drug is effective in women with HER2-overexpressed endometrial cancer or carcinosarcoma that has been treated in the past.

HER2
endocrine therapy
measurable disease
endometrial carcinoma
follicle stimulating hormone
  • 0 views
  • 26 Jan, 2021
  • 6 locations
Efficacy and Safety of Regorafenib as Maintenance Therapy After First-line Treatment in Patients With Bone Sarcomas

This is a randomized, double-blinded, 2 arms study concerning patients with bone sarcoma after the first line therapy. In the first arm, patients will be treated with regorafenib for a maximum of 12 months as maintenance therapy after first line therapy (chemotherapy and surgery), whereas in the second arm, patients …

warfarin
ifosfamide
metastasis
adriamycin
lipase
  • 0 views
  • 24 Jan, 2021
  • 10 locations