Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 217 clinical trials
Eribulin in Angiosarcoma and Epithelioid Hemangioendothelioma (EHE)

This research study is studying a drug as a possible treatment for Angiosarcoma or Epithelioid hemangioendothelioma (EHE). -The drug involved in this study is Eribulin

ct scan
cancer
tumor cells
neutrophil count
systemic therapy
  • 122 views
  • 25 Mar, 2022
Metformin as Maintenance Therapy in Patients With Bone Sarcoma and High Risk of Relapse

Primitive bone sarcoma are rare tumors with low options of therapy for patient treatment. OSTEOSARCOMA VERY POOR RESPONDER COHORT. Necrosis on primitive localized osteosarcoma represents one of the principal prognostic factors. Nowadays, for localized osteosarcoma there is no maintenance therapy that have shown to be effective. In ISG-OS1 study in …

  • 0 views
  • 06 Apr, 2021
  • 1 location
Study of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma

The body has different ways of fighting infections and disease. No single way seems perfect for fighting cancer. This research study combines two different ways of fighting disease: antibodies and T cells. Antibodies are molecules that fight infections and protect your body from diseases caused by bacteria and toxic substances. …

pegfilgrastim
granulocyte colony stimulating factor
tumor cells
cellular therapy
high-risk neuroblastoma
  • 18 views
  • 24 Apr, 2022
  • 1 location
Palbociclib and INCMGA00012 in People With Advanced Liposarcoma

The researchers are doing this study to find out whether combining the study drugs palbociclib and INCMGA00012 is an effective and safe treatment for advanced liposarcoma.

liposarcoma
metastasis
neutrophil count
systemic therapy
measurable disease
  • 0 views
  • 04 Jan, 2022
  • 7 locations
Boron Neutron Capture Therapy Using CICS-1 and SPM-011 for Malignant Melanoma and Angiosarcoma

Among skin malignancies, patients with malignant melanoma or angiosarcoma are treated with BNCT using CICS-1 and SPM-011 (borofalan (10B)). Through this trial, safety and appropriate treatment dose will be determined.

angiosarcoma
skin lesion
cancer
  • 0 views
  • 28 Feb, 2022
  • 1 location
Olaparib With Ceralasertib in Recurrent Osteosarcoma

This study is being done in order to evaluate the effectiveness of using two drugs (olaparib and ceralasertib) to treat patients with osteosarcoma that has not responded to treatment or has come back after treatment The names of the study drugs involved in this study are: Olaparib Ceralasertib

neulasta
kidney function tests
recurrent osteosarcoma
olaparib
cancer
  • 16 views
  • 21 Oct, 2021
  • 2 locations
ZW25 in Women With Endometrial Cancers

This study is being done to test the drug ZW25 and look at whether this drug is effective in women with HER2-overexpressed endometrial cancer or carcinosarcoma that has been treated in the past.

serum pregnancy test
trastuzumab
immunomodulators
endometrial carcinoma
maintenance therapy
  • 0 views
  • 24 Mar, 2022
  • 7 locations
Propranolol in Angiosarcoma

This is a window opportunity study of propranolol in patients with angiosarcoma. The aim of this study is to prospectively evaluate the activity of propranolol in the clinical setting as monotherapy, where the neoadjuvant setting provides a good opportunity to rapidly evaluate both the clinical response and histological response, without …

platelet count
cancer
kidney function tests
systemic therapy
angiosarcoma
  • 0 views
  • 01 Jan, 2022
  • 1 location
A Phase II Study Evaluating Efficacy and Safety of Regorafenib in Patients With Metastatic Bone Sarcomas (REGOBONE)

INDICATION Metastatic bone sarcomas: conventional high grade osteosarcoma, Ewing sarcoma of bone, intermediate or high-grade chondrosarcomas and chordomas and either bone or soft tissue metastatic CIC-rearranged sarcomas

immunomodulators
sarcoma of bone
glomerular filtration rate
lipase
nitrosoureas
  • 42 views
  • 27 Apr, 2022
  • 18 locations
AG-120 in People With IDH1 Mutant Chondrosarcoma

This study is being done to see whether AG-120 is an effective and safe treatment for people with advanced/metastatic or recurrent chondrosarcoma that has IDH1 mutation.

measurable disease
kidney function tests
cancer
neutrophil count
  • 5 views
  • 12 May, 2022
  • 1 location