Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 272 clinical trials
Research of Biomarkers of Response to Proton Beam Therapy in Pediatric and Adult Patients.

This trial is a paucicentric, clinico-biological cohort study with retrospective and prospective enrollment, aiming to identify biomarkers predictive of response to Proton Beam Therapy (PBT) in cancer patients (high grade sarcoma, brain tumors and meningioma). This study include collection of clinical data, of tumor samples (collected during standard of care) …

tumor cells
proton therapy
karnofsky performance status
cancer
eosin
  • 0 views
  • 14 May, 2021
  • 2 locations
Image Assisted Optimization of Proton Radiation Therapy in Chordomas and Chondrosarcomas

Rationale: Chordomas and chondrosarcomas located in the axial skeleton are malignant neoplasms of bone. These tumors share the same clinical challenges, as the effect of the disease is more a function of their local aggressiveness than their tendency to metastasize (20% metastasize). The local aggressive behavior can cause debilitating morbidity …

  • 0 views
  • 16 Apr, 2021
  • 2 locations
Long-Term Longitudinal QoL in Patients Undergoing EEA

This is a prospective longitudinal study to access postoperative 2-year quality of life in patients who undergo endonasal endoscopic approach surgeries of the skull base.

  • 0 views
  • 28 Jun, 2021
  • 1 location
Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plus regenerative osseous surgery. The study will look at the level of function for a period of …

bone graft
n-telopeptide
sarcoma
osteocalcin
  • 28 views
  • 07 Mar, 2021
  • 4 locations
Children and Adolescents With Leukemia Brain Tumors and Sarcomas

Aim of this study is to investigate the influence of social factors on participation and activity among children and adolescents aged 10-18 years with leukemia, brain tumors, and sarcomas. Furthermore personal and treatment-related factors and their impact on participation will be explored

brain tumor
sarcoma
leukemia
  • 17 views
  • 25 Jan, 2021
  • 1 location
Use of Electrical Impedance Spectroscopy (EIS) for Early Diagnosis of Skin Damage

The purpose of this clinical study is to evaluate if the DermaSense prototype EIS scanner can provide medical decision support which can complement dermoscopy-based identification of the disease at time of biopsy decision.

  • 0 views
  • 27 Jan, 2021
  • 1 location
Understanding Communication in Healthcare to Achieve Trust (U-CHAT)

Honest, clear, and empathetic communication between pediatric oncologists (POs) and parents of children with cancer (POCCs) is imperative to facilitating therapeutic alliance and ensuring that medical management aligns with the families' goals of care. Communication is particularly important during conversations about disease reevaluation, which often necessitate parental decision-making in the …

glioblastoma multiforme
brain tumor
solid tumor
cancer
  • 46 views
  • 21 Feb, 2021
  • 1 location
Evaluation of Myocardial Injury After Anthracycline Chemotherapy in Osteosarcoma Patients Using CMR

using a contrast-enhanced (CE) cardiac magnetic resonance imaging(CMR) which included the measurement of T1 mapping, T2 mapping, T2* mapping and late gadolinium enhancement(LGE) sequences, as well as LVEF and extracellular volume(ECV) to evaluate the respective changes before and after anthracycline chemotherapy.

chemotherapy regimen
MRI
cancer chemotherapy
anthracyclines
myocardial injury
  • 5 views
  • 25 Jan, 2021
  • 1 location
Collecting and Storing Tissue From Young Patients With Cancer

This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and …

lymphoid leukemia
lymphoma
sarcoma
leukemia
germ cell tumors
  • 33 views
  • 26 Jan, 2021
  • 26 locations
Localized Leiomyosarcoma Biomarker Protocol

Leiomyosarcoma (LMS) is one of the more common soft tissue sarcomas (STS). Patients presenting with large, high-grade, localized LMS are at significant risk of developing metastasis following curative surgery. Clinical trials of neoadjuvant or adjuvant anthracycline and ifosfamide have suggested that patients with localized STS who are at high-risk of …

cancer chemotherapy
immunomodulators
doxorubicin
combination chemotherapy
leiomyosarcoma
  • 0 views
  • 25 Jun, 2021
  • 4 locations