Sarcoma (Pediatric) Clinical Trials

A listing of Sarcoma (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 231 clinical trials
Featured trial
Seclidemstat in the treatment of Ewing sarcoma and other select sarcomas

If you are eligible and agree to participate, you will receive the investigational (called "study") medication. Whether you receive the study medication alone or with another type of 'standard of care' treatment will depend on your type of sarcoma. The study doctor/staff will talk with you more about this.You will …

  • 0 views
  • 04 Feb, 2022
  • 16 locations
Featured trial
COG D9902: Collecting and Storing Tissue, Blood, and Bone Marrow Samples from Patients with Rhabdomyosarcoma or Other Soft Tissue Sarcoma

COG D9902: Collecting and Storing Tissue, Blood, and Bone Marrow Samples from Patients with Rhabdomyosarcoma or Other Soft Tissue Sarcoma

  • 224 views
  • 08 Nov, 2020
  • 1 location
Surgery With Our Without Neoadjuvant Chemotherapy in High Risk RetroPeritoneal Sarcoma

This is a multicenter, randomized, open label phase lll trial to assess whether preoperative chemotherapy, as an adjunct to curative-intent surgery, improves the prognosis of high risk DDLPS (dedifferentiated Liposarcoma) and LMS (Leiomyosarcoma) patients as measured by disease free survival. After confirmation of eligibility criteria, patients will be randomized to …

systemic therapy
ifosfamide
liposarcoma
tubal occlusion
dedifferentiated liposarcoma
  • 0 views
  • 30 Jul, 2021
  • 23 locations
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Desmoplastic Small Round Cell Tumor

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory desmoplastic small round cell tumor (DSRCT) in children and young adults. This trial is part of the CAMPFIRE master protocol which is a platform …

kidney function tests
vinorelbine
desmoplastic
cancer
neutrophil count
  • 4 views
  • 15 Jun, 2022
  • 54 locations
Molecular Profiling of Advanced Soft-tissue Sarcomas (MULTISARC)

MULTISARC is a randomized multicenter study assessing whether high throughput molecular analysis (next generation sequencing exome - NGS) is feasible in advanced/metastatic soft-tissue sarcoma patients, that is, whether NGS can be conducted for a large proportion of patients, with results available within reasonnable delays. In parallel, MULTISARC aims to assess …

BRAF
KIT
carcinoma
cancer chemotherapy
measurable disease
  • 15 views
  • 16 Feb, 2022
  • 11 locations
A Study Comparing the Efficacy of L19TNF+Doxorubicin vs Doxorubicin Alone as First-line Therapy in Patients With Advanced or Metastatic Soft Tissue Sarcoma (FIBROSARC)

The present study is an open-label, randomized, controlled, two-arm multi-center study of the efficacy of L19TNF treatment in combination with doxorubicin versus doxorubicin alone in advanced or metastatic soft-tissue sarcoma patients. In the study, 102 patients will be randomized in a 1:1 ratio to receive doxorubicin treatment (Arm 1) or …

  • 0 views
  • 21 Apr, 2022
  • 6 locations
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma (CHIC-STS01)

Phase III, multicenter, randomized open-label and comparative study designed to demonstrate whether adding 4 cycles of peri-operative doxorubicin-based chemotherapy improves metastasis-free survival as compared with standard management in patients with resectable STS, considered as high-risk according to CINSARC (Complexity Index in SARComas) signature. After signed informed consent, patients considered as …

ifosfamide
kidney function tests
metastasis
platelet count
doxorubicin
  • 0 views
  • 11 May, 2022
  • 20 locations
Study of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 Mutations

This is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1) arginine 130 (R132)-mutant advanced solid tumors, including but not limited to cholangiocarcinoma, chondrosarcoma, and glioma or isocitrate dehydrogenase 2 (IDH2) arginine 140 (R140) or arginine …

systemic therapy
metastasis
arginine
cancer chemotherapy
gemcitabine
  • 14 views
  • 13 Jun, 2022
  • 35 locations
Phase III Trial of Anlotinib, Catequentinib in Advanced Alveolar Soft Part Sarcoma, Leiomyosarcoma, Synovial Sarcoma (APROMISS) (APROMISS)

THIS STUDY IS CURRENTLY RECRUITING PATIENTS WITH ALVEOLAR SOFT PART SARCOMA ONLY AND IS NO LONGER RECRUITING PATIENTS WITH SYNOVIAL SARCOMA OR LEIOMYOSARCOMA. This study evaluates the safety and efficacy of AL3818 (anlotinib) hydrochloride in the treatment of metastatic or advanced alveolar soft part sarcoma (ASPS), leiomyosarcoma (LMS), and synovial …

alveolar soft part sarcoma
systemic therapy
platelet count
anthracyclines
neutrophil count
  • 334 views
  • 27 Jan, 2022
  • 22 locations
Development of Clinical and Biological Database (BCBInstitut)

The BCB is a tool: for research in analytical and public health epidemiology, biological research and for the development of data useful for clinical research and therapeutic trials; to help scientists understand and explain phenomena ranging from the interaction of molecules to the whole metabolism of the organism in normal …

gastrointestinal cancer
anal canal
sarcoma
breast cancer
cancer
  • 4 views
  • 27 Feb, 2022
  • 1 location