Bipolar Disorders (Pediatric) Clinical Trials

A listing of Bipolar Disorders (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Improving Adherence in Adolescents and Young Adults With Bipolar Disorder (IGNITE)

Although poor medication adherence occurs in more than 65% of adolescent and young adults (AYA) with bipolar disorder (BD) and is associated with poor recovery, high rates of relapse, and a 5.2 fold increased suicide risk, there have been no interventions that specifically target adherence in AYA with BD. This …

structured clinical interview
suicide
antipsychotics
scid
valproic acid
  • 0 views
  • 21 Oct, 2022
  • 2 locations
Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms

The lifetime prevalence of Bipolar II is 0.4% with the time spent with depressive symptoms outnumbering the time spent with hypomanic symptoms by 35 to 1. Regarding current treatment options, psychotherapy is effective for managing depressive symptoms, with CBT being particularly efficacious. Unfortunately, CBT is often not a feasible treatment …

depressed mood
depression
depressive episode
psychotherapy
depressive symptoms
  • 9 views
  • 29 Oct, 2022
  • 1 location
Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression (LFMSBioMGeri)

The protocol involves functional Magnetic Resonance Imaging and Magnetic Resonance Spectroscopy acquisitions immediately before and after Low Field Magnetic Stimulation treatment on two separate days in a sham controlled, randomized trial, in order to assess the physiologic effects of Low Field Magnetic Stimulation on brain function in a geriatric population …

bipolar disorder
magnetic resonance spectroscopy
psychotropic
depression
depressed mood
  • 86 views
  • 04 Oct, 2022
  • 1 location
Clinical Medication Development for Bipolar Disorder and Alcohol Use Disorders

Preclinical and clinical data as well as mechanistic justification have been presented suggesting citicoline and pregnenolone are each promising treatments for alcohol use in BPD. Both appear to have favorable side effect profiles and no known drug-drug interactions. Thus, they have the potential to be safely used in a dual …

valproate
caffeine
substance use
oxcarbazepine
lamotrigine
  • 1230 views
  • 04 Oct, 2022
  • 1 location
Imaging GABAergic/Glutamatergic Drugs in Bipolar Alcoholics Alcoholics

The proposed 3-week, double-blind, crossover, proof of concept study aims to manipulate neurochemical dysfunctions characteristic of individuals with co-occurring BD and AUD (i.e., abnormally low prefrontal GABA and glutamate), using medications that have been shown to normalize cortical GABA (i.e., gabapentin) and glutamate (i.e., NAC) levels in past research, and …

bipolar disorder
acetylcysteine
n-acetylcysteine
alcohol use disorder
gabapentin
  • 200 views
  • 04 Oct, 2022
  • 1 location
Time,Self and Spontaneous Mental Activities in Patients With Psychotic Disorders

The main purpose of the study is to examine to which extent abnormalities in the dynamics of neural activities observed in patients with psychosis is related to difficulties at ordering simple visual stimuli and/or personal events.

bipolar disorder
schizophrenia
psychosis
  • 15 views
  • 04 Oct, 2022
Triple Chronotherapy in Adolescents (TCT-RCT)

Study Purpose This study is a randomized controlled trial examining the effectiveness of TCT in the acute treatment of depression and suicidality in adolescents compared to usual treatment care, which includes individual and group therapy, and medication adjustments. All potential participants will be identified at admission to the Psychiatric Youth …

severe depression
insomnia
suicidal
depression
depressed mood
  • 15 views
  • 04 Oct, 2022
  • 1 location
Intervention for Comorbid Substance Use and Bipolar Disorders (ITAP)

This trial aims to evaluate the effectiveness of a novel intervention for patients with co-occurring bipolar and substance use disorders following a psychiatric hospitalization. Half of the participants will receive a specialized psychosocial intervention program, while the other half will receive an enhanced safety monitoring program, both provided in addition …

substance use disorder
bipolar disorder
substance use
psychiatric hospitalization
  • 9 views
  • 04 Oct, 2022
  • 1 location
Post-Hospital Intervention for Veterans With Comorbid Bipolar and Substance Use Disorders

This trial aims to evaluate the effectiveness of a novel intervention for Veterans with co-occurring bipolar and substance use disorders following a psychiatric hospitalization. Half of the participants will receive a specialized psychosocial intervention program, while the other half will receive an enhanced safety monitoring program, both provided in addition …

mood disorder
substance use
  • 0 views
  • 07 Oct, 2022
  • 1 location
Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response

The proposed study will assess the combined effect of perampanel and ketamine on the anti-depressant response in individuals with treatment resistant depression. The purpose of this study is to test the hypothesis that stimulation of Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid receptors (AMPAR) is critical to the anti-depressant response of ketamine.

caffeine
structured clinical interview
psychotherapy
depressive symptoms
scid
  • 379 views
  • 04 Oct, 2022
  • 1 location