Abnormal Blood Vessels (Arteriovenous Malformations) Clinical Trials

A listing of Abnormal Blood Vessels (Arteriovenous Malformations) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 30 clinical trials
Biology and Genetics of Human Brain Arteriovenous Malformations

Patients eligible for enrollment in this study will be from the Northwell Neurosurgery practice. We propose to enroll an initial set of 10 BAVM patients and 10 epilepsy patients in the first year.  After this time, assessment will be made to determine the additional number of patients to be enrolled. We …

  • 12 Aug, 2020
  • 1 location
A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine

A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of CCX168 (Avacopan) in Patients with Anti-Neutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis Treated Concomitantly with Rituximab or Cyclophosphamide/Azathioprine

  • 25 Mar, 2021
  • 1 location
Treatment of Brain AVMs (TOBAS) Study

The objectives of this study and registry are to offer the best management possible for patients with brain arteriovenous malformations (AVMs) (ruptured or unruptured) in terms of long-term outcomes, despite the presence of uncertainty. Management may include interventional therapy (with endovascular procedures, neurosurgery, or radiotherapy, alone or in combination) or …

brain disorders
endovascular procedure
endovascular procedures
  • 25 Jan, 2021
  • 33 locations
The Effectiveness of FRAME FR for AVF Repair in High-Flow Reduction & Stabilization A Prospective Trial

Patients with end-stage renal disease require permanent vascular access to enable safe and effective hemodialysis. An arteriovenous fistula (AVF), where a vein is mobilized and connected to an artery in the arm, is considered the gold standard and first choice for vascular access. After fistula creation, the vein is subjected …

  • 25 Apr, 2021
  • 1 location
Post Approval Study Investigating Lutonix Drug Coated Balloon for Treatment of Dysfunctional Arteriovenous Fistulae

This prospective, global, multicenter, single arm post-approval study is designed to investigate the clinical use and safety of the Lutonix 035 AV Drug Coated Balloon (DCB) PTA Catheter in subjects presenting with clinical and hemodynamic abnormalities in native arteriovenous (AV) fistulae located in the upper extremity.

renal disease
  • 19 Apr, 2021
  • 12 locations
Home Hemodialysis Assisted by a Nurse for Arterio-venous Fistula Cannulation

Home HD (HHD) is associated with better outcome in end-stage renal disease patients compared to in-center HD, in particular in terms of quality of life. However fear of AVF cannulation is a known barrier for patient's choice and adoption of a HHD program. Providing nurse assistance for the cannulation can …

renal disease
  • 06 Mar, 2021
  • 1 location
PHIL Embolic System Pediatric IDE

The purpose of this study is to collect information about how the PHIL Embolic System works in the treatment of intracranial dural arteriovenous fistulas. Data collected in this study will be used to evaluate the safety and probable benefits in treating DAVFs. The PHIL Embolic System is a Humanitarian Use …

  • 27 Jan, 2021
  • 1 location
Prospective Evaluation of the Efficacy of Sirolimus (Rapamune ) in the Treatment of Severe Arteriovenous Malformations

The aim of the study is to evaluate the efficacy and safety of sirolimus (oral form), to decrease the volume and symptoms due to superficial arteriovenous malformations (AVM). Sirolimus has properties that reduce the activity of the immune system (immunosuppressant), to fight against the proliferation of cancer cells (anti- tumor) …

  • 24 Jan, 2021
  • 13 locations
Proton Radiotherapy for Primary Central Nervous System Tumours in Adults

Open label, multi-centre prospective study. Adult patients with primary central nervous system tumours fulfilling the inclusion criteria according to the study protocol. The study consists of 2 sequential cohorts evaluated consecutively for the feasibility, safety and toxicity, as well as long-term survival data, when using spot scanning proton beam therapy.

nervous system tumours
  • 21 Jan, 2021
  • 5 locations
Treating Arteriovenous Malformation With Stereotactic Radiosurgery Using CT Angiography for Treatment Planning

Evaluate whether a treatment plan based on CT angiography can accurately and precisely identify the target nidus as compared to standard cerebral arteriography fused to MRI.

stereotactic radiotherapy
tubal ligation
renal function
ct angiography
spinal cord
  • 30 Apr, 2021
  • 1 location