Cerebral Palsy Clinical Trials

The CHAMP Study—a multisite clinical trial funded by the National Institutes of Health—compares the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy, also known as hemiparetic cerebral palsy. Children who meet study eligibility criteria will participate at one of the three clinical sites— Roanoke, Virginia; Charlottesville, ...

The Baby Champ Study, a clinical trial funded by the National Institutes of Health, compares three highly promising forms of therapy for infants and toddlers who have a diagnosis of hemiparetic cerebral palsy. Children who meet study eligibility criteria will participate at one of the two clinical sites: Roanoke, Virginia, ...

The purpose of the study is to understand the needs of aging people with long-term physical disability. Participation includes 3 surveys either online or via phone. The surveys take 30 – 45 minutes each to complete.  A $16.00 gift card is provided for each completed survey (IRB # 201710186).  

Protocol Outline: Patents undergo surgery in which electrodes are implanted into muscles of the trunk and legs. Electrode leads are connected to an stimulator/telemeter. Following implantation, patients undergo training in standing, transfers and other advanced mobility skills using the functional electrical stimulation system. A prescribed course of exercise, functional training ...

A pilot study ECOCAPTURE (ClinicalTrials.gov/NCT02496312, 2015) applied to a group of participants with the behavioural variant of frontotemporal lobar degeneration (bvFTLD) matched for age, gender and level of education to healthy participants (n=7 per group). This pilot validated the concept of ECOCAPTURE. The purpose of this trial is to continue ...

Specific Aim #1: To compare the effectiveness of an intense physiotherapy program with the current standard of care in the management of children with spastic cerebral palsy. Hypothesis #1: Children receiving a short cluster of intense therapies (5 times per week for 12 weeks) will show greater functional gains as ...

Analysis of spontaneous movements in young infants from video recordings is recommended as an early medical assessment tool for prediction of cerebral palsy in high-risk infants. Such video recording have previously been performed in follow-up programs at hospitals using semi standardized video set-ups. The research group behind this study develops ...

Constraint-induced movement therapy (CIMT) is a short-term, intensive treatment to promote functional arm and hand skills in people with hemiparesis. It usually involves constraint of the non-involved extremity and intensive movement practice of the weaker extremity.

Determining optimal frequency of treatment for young children with cerebral palsy (CP) has implications for shaping the future of pediatric rehabilitation. There are wide variations in the number of hours per week of treatment in current outpatient rehabilitation programs for children with CP, suggesting clinical uncertainty. Usual weekly therapy at ...

Purpose To create a brain atlas that will allow physiological and clinical information to be assigned to anatomical locations in MRI space, utilizing non-rigid MRI normalization algorithms. These data will specifically be acquired from the population of patients undergoing stereotactic brain procedures. 2. To collate and analyze the brain data ...