Cerebral Palsy Clinical Trials

The CHAMP Study—a multisite clinical trial funded by the National Institutes of Health—compares the efficacy of alternative therapies for young children with unilateral spastic cerebral palsy, also known as hemiparetic cerebral palsy. Children who meet study eligibility criteria will participate at one of the three clinical sites— Roanoke, Virginia; Charlottesville, ...

The Baby Champ Study, a clinical trial funded by the National Institutes of Health, compares three highly promising forms of therapy for infants and toddlers who have a diagnosis of hemiparetic cerebral palsy. Children who meet study eligibility criteria will participate at one of the two clinical sites: Roanoke, Virginia, ...

Researchers are Inviting You to Participate in A Research Study about Early Intervention Services for Young Children with Delayed Motor Development  

The purpose of the study is to understand the needs of aging people with long-term physical disability. Participation includes 3 surveys either online or via phone. The surveys take 30 – 45 minutes each to complete.  A $16.00 gift card is provided for each completed survey (IRB # 201710186).  

Balance and gait problems in subjects with neurological disease lead to reduced mobility, loss of independence and frequent falls. Treadmill training is a widely used form of treatment and it has been used in subjects with neurological disease to ameliorate walking and balance deficits. The Virtual Reality Treadmill as a ...

Purpose To create a brain atlas that will allow physiological and clinical information to be assigned to anatomical locations in MRI space, utilizing non-rigid MRI normalization algorithms. These data will specifically be acquired from the population of patients undergoing stereotactic brain procedures. 2. To collate and analyze the brain data ...

Frontal patients are impaired in categorisation and analogical reasoning tasks, and different functional imaging studies from our group have shown the involvement of the prefrontal cortex in categorisation and analogy tasks. The aim of this project is to test our hypotheses about the role of the prefrontal cortex in explicit ...

The purpose of this study is to evaluate the safety and initial effectiveness of MRI-guided focused ultrasound thermal ablation of a designated area in the brain of patients suffering from movement disorder symptoms: FUS under MRI-guidance and MRI-based thermometry can be safely delivered to patients suffering from treatment-refractory movement disorders ...

A pilot study ECOCAPTURE (ClinicalTrials.gov/NCT02496312, 2015) applied to a group of participants with the behavioural variant of frontotemporal lobar degeneration (bvFTLD) matched for age, gender and level of education to healthy participants (n=7 per group). This pilot validated the concept of ECOCAPTURE. The purpose of this trial is to continue ...

Specific Aim #1: To compare the effectiveness of an intense physiotherapy program with the current standard of care in the management of children with spastic cerebral palsy. Hypothesis #1: Children receiving a short cluster of intense therapies (5 times per week for 12 weeks) will show greater functional gains as ...