Kidney Disease (Pediatric) Clinical Trials

A listing of Kidney Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 45 clinical trials
A Phase 2b Diabetic Kidney Disease Study

A Phase 2b Randomized, Double-blind, Placebo-controlled, Study to Evaluate the Efficacy and Safety of MEDI3506 in Subjects with Diabetic Kidney Disease

diabetic nephropathy
nephropathy
  • 456 views
  • 04 Oct, 2022
  • 75 locations
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States (GUARDD-US)

The primary aim is to determine the effect of participant and provider knowledge of a positive APOL1 status and accompanying guideline based clinical decision support (CDS) on blood pressure management on change in systolic blood pressure (SBP) from baseline to 3 months after randomization among the APOL1 positive participants. Secondary …

antihypertensive drugs
apolipoprotein l1
diabetes
hemoglobin a1c
hypertension
  • 6 views
  • 12 Oct, 2022
  • 10 locations
Atrasentan in Patients With Proteinuric Glomerular Diseases (AFFINITY)

The AFFINITY Study is a phase 2, open-label, basket study to evaluate the efficacy and safety of atrasentan in patients with proteinuric glomerular disease who are at risk of progressive loss of renal function.

type 2 diabetes
corticosteroids
sglt2
atrasentan
immunosuppressants
  • 31 views
  • 04 Oct, 2022
  • 36 locations
A Phase 1, Open-label, Dose-escalation and Dose-expansion Study to Evaluate the Safety, Tolerability Pharmacokinetics Immunogenicity, and Antitumor Activity of MEDI5752 in Subjects With Advanced Solid Tumors.

The purpose of this study is to evaluate MEDI5752 and carboplatin and pemetrexed or paclitaxel or nab-paclitaxel in adult subjects with advanced solid tumors, when administered as a single agent or combined with chemotherapy.

carboplatin
progressive disease
cancer
pemetrexed
solid tumors
  • 200 views
  • 21 Oct, 2022
  • 29 locations
APL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid Tumors (SPARTA)

The primary Phase 1 purpose of this study was to assess overall safety, tolerability and recommended Phase 2 dose (RP2D) of APL-101. The Phase 2 portion will assess efficacy of the dose determined in Phase 1 in individuals with Non-Small Cell Lung Cancer with c-Met EXON 14 Skip Mutations; individuals …

lung cancer
solid tumour
solid neoplasm
cancer
epidermal growth factor
  • 326 views
  • 04 Oct, 2022
  • 85 locations
Evaluation of Pain Before and After Removal of Non-obstructive Kidney Stones (ENORC)

Pain associated with renal stone disease is typically caused by an obstructing stone that obstructs the flow of urine, which results in renal collecting system dilatation. Non-obstructing renal calculi that do not cause renal collecting system dilatation are thought to be painless. The objective of this study is to prospectively …

colic
  • 66 views
  • 04 Oct, 2022
  • 9 locations
Dietary Oxalate and Immune Cell Function

The purpose of this study is to evaluate mitochondrial function in white blood cells and platelets from healthy individuals following dietary oxalate intake.

oxalate
Accepts healthy volunteers
  • 74 views
  • 11 Oct, 2022
  • 1 location
MIP Versus PCNL for Kidney Stone Disease

The decision to use standard percutaneous nephrolithotomy (PCNL) versus mini-percutaneous nephrolithotomy (MIP) has been a subject of much debate in the urological community. The investigators propose a randomized controlled trial to compare the operative outcomes and complications of mini-percutaneous nephrolithotomy (mini-PCNL) versus standard PCNL for renal stones. The results of …

ct scan
  • 0 views
  • 04 Oct, 2022
  • 6 locations
Impact of a Ciclosporin A Preconditioning for Prevention of Ischemia-reperfusion Injury After Renal Artery Stenosis Dilation (CicloSAAR)

Renal artery stenosis is one the leading cause of secondary hypertension. Previous randomized controlled trials in humans have failed to demonstrate an improvement of renal function after stenosis dilation, probably because of a selection bias with more severe patients being excluded from randomization. Renal ischemia-reperfusion injuries have also not been …

ischemia
stenosis
glomerular filtration rate
renal artery stenosis
hypertension
  • 6 views
  • 20 Oct, 2022
  • 1 location
Safety and Effectiveness of the Ultrasonic Propulsion of Kidney Stones

A feasibility study to test the ability to move kidney stones using focused ultrasound. It is the goal of our technology to: a) move stone fragments to a location within the kidney to improve their chances of passage, and thus reduce the occurrence of additional symptomatic events and retreatment or …

lithotripsy
ct scan
focused ultrasound
nephrolithiasis
  • 1 views
  • 04 Oct, 2022
  • 1 location