Kidney Disease (Pediatric) Clinical Trials

A listing of Kidney Disease (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 23 clinical trials
Ultrasonic vs. Fluoroscopic Guided PNL in Pediatric Renal Stones

Percutaneous Nephrolithotomy (PNL) was accepted as a treatment modality for large renal stones since 1980. Although radiation exposure during PNL is within the safe limits for expert endourologist, the mutagenic hazard is still present especially in pediatric population. Therefore, employing an alternative imaging technique during PNL would be of added …

  • 3 views
  • 01 Aug, 2021
  • 1 location
A Study to Test the Effect of Different Doses of BI 685509 on Kidney Function in People With Diabetic Kidney Disease

This study is open to adults with diabetic kidney disease. The purpose of the study is to find out whether a medicine called BI 685509 improves kidney function. Three different doses of BI 685509 are tested in this study. Participants get either one of the three doses of BI 685509 …

angiotensin
angiotensin converting enzyme
antihypertensive drugs
albumin/creatinine ratio
diabetes
  • 0 views
  • 01 Aug, 2021
  • 36 locations
Genetic Testing to Understand and Address Renal Disease Disparities Across the United States

The primary aim is to determine the effect of participant and provider knowledge of a positive APOL1 status and accompanying guideline based clinical decision support (CDS) on blood pressure management on change in systolic blood pressure (SBP) from baseline to 3 months after randomization among the APOL1 positive participants. Secondary …

hemoglobin a1c
antihypertensive drugs
apolipoprotein l1
diabetes
hypertension
  • 0 views
  • 25 Jul, 2021
  • 9 locations
A Study to Evaluate MEDI5752 in Subjects With Advanced Solid Tumors

The purpose of this study is to evaluate MEDI5752 in adult subjects with advanced solid tumors, when administered as a single agent or combined with chemotherapy.

cancer treatment
pembrolizumab
programmed cell death 1 ligand 1
cancer chemotherapy
cancer
  • 160 views
  • 29 Jul, 2021
  • 36 locations
Adapting Multiple Behavior Interventions That Effectively Improve Cancer Survivor Health Cancer Survivor Health

This research study will test the efficacy of interactive, web-based interventions that improve diet, physical activity and weight management changes among early stage survivors of breast, prostate, colorectal, endometrial, renal, and ovarian cancers. Overarching outcomes also include physical function and performance, muscle mass, quality of life, and health utilities.

carcinoma
cancer chemotherapy
cancer of the ovary
cancer
hypertension
  • 42 views
  • 31 Jul, 2021
  • 2 locations
Comparison of SP TFL and Ho:YAG for RIRS Using 145 m and 200 m Fibers

The authors hypothesize that the RIRS using 150-microm Tm-fiber laser is superior than fiber with larger diameters, as 200-microm Tm-fiber laser or 200-microm holmium fiber laser, in such points as follows: decreasing surgery time and laser-on time due to possibility of 4.3 fold ablation efficacy increase, which has been shown …

lithotripsy
nephrolithiasis
  • 0 views
  • 01 Aug, 2021
  • 1 location
NEPHSTROM for Diabetic Kidney Disease

The study will investigate, primarily, the safety, feasibility and tolerability and, secondarily, the preliminary efficacy of an allogeneic bone marrow-derived Mesenchymal Stromal Cell (MSC) therapy (ORBCEL-M) in study subjects with type 2 diabetes (T2D) and progressive diabetic kidney disease (DKD).

nephropathy
diabetes
diabetic nephropathy
type 2 diabetes mellitus
  • 188 views
  • 26 Jul, 2021
  • 5 locations
Influence of Obesity on Endogenous Oxalate Synthesis

There is increasing evidence that obesity is associated with increased urinary oxalate excretion, an important risk factor for calcium oxalate stone formation. By the administration of a controlled low oxalate diet the investigators will estimate endogenous oxalate synthesis in both non-obese and obese non-kidney-stone forming adults. This study seeks to …

controlled diets
body mass index
calcium
oxalate
  • 30 views
  • 31 Jul, 2021
  • 1 location
The Effect of Etelcalcetide on CKD-MBD

The proposed study will investigate the effects of etelcalcetide on the bone and blood-vessel health in patients with CKD-MBD. The investigators will test if etelcalcetide makes bone and blood-vessels healthier. The study hypotheses are that are that etelcalcetide keeps bones strong and lowers the risk of calcium deposits in blood …

dialysis
cinacalcet
maintenance haemodialysis
urea
  • 12 views
  • 19 Jul, 2021
Effects of the SGLT2 Inhibitor Empagliflozin in Patients With Euvolemic and Hypervolemic Hyponatremia

Hyponatremia is the most common electrolyte derangement occurring in hospitalized patients. It is usually classified as hypovolemic, euvolemic or hypervolemic. The most common aetiology of euvolemic hyponatremia is the syndrome of inappropriate antidiuresis (SIAD). Hypervolemic hyponatremia is common in patients with congestive heart failure (CHF) (10-27%) and liver cirrhosis (up …

serum sodium
heparin
cirrhosis
empagliflozin
fluid restriction
  • 0 views
  • 01 Aug, 2021
  • 1 location