Habit Reversal Clinical Trials

A listing of Habit Reversal medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 11 clinical trials
A Study of Selexipag as Add-On Treatment to Standard of Care in Children With Pulmonary Arterial Hypertension

The purpose of this study is to evaluate whether the addition of selexipag to standard of care treatment delays disease progression in children with Pulmonary Arterial Hypertension (PAH) in comparison to placebo.

primary pulmonary hypertension
endothelin receptor antagonist
heart disease
right heart catheterization
endothelin
  • 169 views
  • 18 Jul, 2021
  • 150 locations
A Study for the Identification of Biomarker Signatures for Early Detection of Pulmonary Hypertension (PH)

The primary purpose of this study is to identify and develop biomarker signatures based on circulating micro ribonucleic acid (RNA) in the blood samples associated with high risk of pulmonary hypertension (PH) to assist in the diagnosis of PH; to estimate the sensitivity, specificity, positive predictive value, and negative predictive …

right heart catheterization
  • 572 views
  • 18 Jul, 2021
  • 88 locations
A Study of the Efficacy and Safety of MK-5475 in Participants With Pulmonary Arterial Hypertension (INSIGNIA-PAH: Phase 2/3 Study of an Inhaled sGC Stimulator in PAH) (MK-5475-007)

This is a two-part (Phase 2/Phase 3) study of MK-5475, an inhaled soluble guanylate cyclase stimulator, in participants with pulmonary arterial hypertension (PAH). The first part (Phase 2) will assess three different doses of MK-5475 compared to placebo; the treatment dose with the best efficacy and safety profile will be …

heart disease
right heart catheterization
left ventricular end-diastolic pressure
pulmonary arterial hypertension
body mass index
  • 0 views
  • 28 Jul, 2021
  • 17 locations
A Study of Selexipag in Participants Who Participated in a Previous Selexipag Study

The purpose of this study is to assess the long-term safety of selexipag while providing continued selexipag treatment for participants who were previously enrolled in an Actelion-sponsored study with selexipag and who derived benefit from selexipag in indications for which a positive benefit-risk has been established.

  • 0 views
  • 20 Jul, 2021
  • 14 locations
A Study Evaluating the Efficacy and Safety of Ralinepag to Improve Treatment Outcomes in PAH Patients

Study ROR-PH-301, ADVANCE OUTCOMES, is designed to assess the efficacy and safety of ralinepag when added to pulmonary arterial hypertension (PAH) standard of care or PAH-specific background therapy in subjects with World Health Organization (WHO) Group 1 PAH.

digoxin
diuretics
hypertension
angiotensin
right heart catheterization
  • 5462 views
  • 26 Jul, 2021
  • 297 locations
A Study of Ralinepag to Evaluate Effects on Exercise Capacity by CPET in Subjects With WHO Group 1 PH

Study ROR-PH-302, ADVANCE CAPACITY, is designed to evaluate the effects of ralinepag therapy on exercise capacity as assessed by change in peak oxygen consumption (VO2) derived from cardiopulmonary exercise testing (CPET) after 28 weeks of treatment

ralinepag
diuretics
endothelin receptor antagonist
exercise stress test
endothelin
  • 0 views
  • 29 Jul, 2021
  • 31 locations
Study of Angiogenic Cell Therapy for Progressive Pulmonary Hypertension: Intervention With Repeat Dosing of eNOS-enhanced EPCs

The SAPPHIRE clinical trial seeks to establish the efficacy and safety of repeated monthly dosing of autologous EPCs transfected with human eNOS (heNOS) in patients with symptomatic severe PAH on available PAH-targeted medical therapy.

oxygen saturation
right heart catheterization
left ventricular end-diastolic pressure
congenital heart defects
assisted ventilation
  • 10 views
  • 20 Jul, 2021
  • 9 locations
Pedometers and Walking Tests for Pulmonary Hypertension Patients

Concordance between walking tests and pedometer data may seem like a logical outcome for pulmonary hypertension (PH) patients. However, many individuals have discordant results: results much worse or better during an in-hospital walking test as compared to real life activity. The primary objective of this study is: to determine variables …

  • 0 views
  • 17 Jul, 2021
  • 1 location
Dronabinol in Trichotillomania and Other Body Focused Repetitive Behaviors

The goal of the proposed study is to evaluate the efficacy and safety of dronabinol in trichotillomania and other body-focused repetitive behaviors such as skin-picking disorder. 50 subjects with DSM-5 trichotillomania or skin-picking disorder will receive 10 weeks of double-blind dronabinol or placebo. The hypothesis to be tested is that …

trichotillomania
  • 28 views
  • 29 Jul, 2021
  • 1 location
Natural History Study of Biomarkers in Pulmonary Arterial Hypertension

Background High blood pressure in the lungs, known as pulmonary arterial hypertension (PAH), is a rare disorder. Some people have disease-associated PAH and some have PAH from an unknown cause. Researchers want to follow the natural history of all PAH patients to understand how PAH progresses in order to discover …

hypertension
left ventricular end-diastolic pressure
pulmonary function test
walk tests
pulmonary arterial hypertension
  • 49 views
  • 28 Jul, 2021
  • 1 location