Epilepsy (Pediatric) Clinical Trials

A listing of Epilepsy (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 141 clinical trials
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Stereotactic Laser Ablation for Temporal Lobe Epilepsy -SLATE-

The SLATE study is a prospective, single-arm, multicenter study. The study is being conducted to evaluate the safety and efficacy of the Visualase® MRI Guided Laser Ablation System.  

seizure
  • 97 views
  • 11 Jun, 2020
  • 1 location
featured
Stereotactic Laser Ablation for Temporal Lobe Epilepsy (SLATE)

The purpose of this study is to evaluate the safety and efficacy of the Visualase MRI Guided Laser Ablation System for narcotization or coagulation of epileptogenic foci in patients with intractable mesial temporal lobe epilepsy (MTLE)  

seizure
temporal lobe epilepsy
  • 32 views
  • 23 Nov, 2020
  • 1 location
Social Cognition in Pediatric Epilepsy

The purpose of this study is to investigate the development of social cognition skills in pediatric epilepsy compared to healthy children. There are evidences indicating that children with epilepsy have executive dysfunctions and language problems. Executive functions refer to multiple cognitive processes that contribute to human higher order abilities, such …

  • 1 views
  • 17 Apr, 2021
  • 1 location
A Study to Evaluate XEN1101 as Adjunctive Therapy in Focal Epilepsy

The XEN1101 Phase 2 clinical trial is a randomized, double-blind, placebo-controlled study that will evaluate the clinical efficacy, safety and tolerability of increasing doses of XEN1101 administered as adjunctive treatment in adult patients diagnosed with focal epilepsy, followed by an optional open-label extension (OLE).

adjunctive treatment
seizure
adjunctive therapy
  • 104 views
  • 25 Jan, 2021
  • 82 locations
Incorporating Multidimensional Psychosocial Interventions Improves the Well-being of Individuals With Epilepsy

The purpose of this study is to incorporate multidimensional self-management programs into the routine care of epilepsy patients. Consenting patients will enroll in one of four interventions that help improve medication adherence, increase seizure awareness and documentation, improve memory and deal with stress and depression.

seizure
  • 72 views
  • 01 Apr, 2021
  • 1 location
Epilepsy Adherence in Children and Technology (eACT)

Fifty-eight percent of children with new-onset epilepsy do not take their antiepileptic drugs (AEDs) as prescribed, which is associated with continued seizures, mortality, poor quality of life, and high healthcare costs. Evidence-based adherence interventions are lacking and critically needed, especially for children with epilepsy, who represent an underserved population in …

seizure
antiepileptics
  • 15 views
  • 24 Jan, 2021
  • 4 locations
A Study to Test the Safety and Tolerability of Brivaracetam in Pediatric Study Participants With Seizures

The purpose of the study is to evaluate the long-term safety and tolerability of brivaracetam.

electroencephalogram
seizure
brivaracetam
antiepileptics
  • 0 views
  • 01 Aug, 2021
  • 21 locations
Medtronic Deep Brain Stimulation (DBS) Therapy for Epilepsy Post-Approval Study (EPAS)

The purpose of this post-approval study is to further evaluate the long-term safety and effectiveness of Medtronic DBS therapy for epilepsy on seizure reduction in newly implanted participants through 3 years of follow-up in different geographic populations.

electroencephalogram
seizure
video eeg
antiepileptics
tonic
  • 0 views
  • 01 Aug, 2021
  • 16 locations
Prevention of Epilepsy by Reducing Neonatal Encephalopathy

The aim of the study is to examine if a pragmatic, evidenced based and generalisable intrapartum care bundle involving birth companions and empowering mothers will reduce birth injury-related epilepsy at 18 months of age in India. The care bundle will have four key elements (interventions): (1) birth companion providing constant …

electroencephalogram
  • 0 views
  • 25 Jan, 2021
  • 3 locations
Bridging the Childhood Epilepsy Treatment Gap in Africa

About half of the world's children with epilepsy do not receive treatment - known as the epilepsy treatment gap - with significantly higher rates (67%-90%) in low- and middle-income countries (LMICs). We will conduct the first cluster-randomized clinical trial (cRCT) to determine the efficacy, implementation, and cost-effectiveness of a novel …

seizure
  • 0 views
  • 29 Mar, 2021
  • 3 locations