Bronchiectasis Clinical Trials

A listing of Bronchiectasis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 11 clinical trials
A Study to Assess the Efficacy Safety and Tolerability of Brensocatib in Participants With Non-Cystic Fibrosis Bronchiectasis

The primary objective of this study is to evaluate the effect of brensocatib at 10 mg and 25 mg compared with placebo on the rate of pulmonary exacerbations (PEs) over the 52-week treatment period.

  • 3 views
  • 01 Aug, 2021
  • 259 locations
Study of Safety Tolerability Pharmacokinetics and Pharmacodynamics of QBW251 in Subjects With Bronchiectasis

The purpose of this study is to determine whether potentiating the cystic fibrosis transmembrane conductance regulator (CFTR) with QBW251 in patients with bronchiectasis will demonstrate

spirometry
grip
cough
pulmonary function test
macrolides
  • 0 views
  • 01 Aug, 2021
  • 9 locations
A Study in Patients With Non-cystic Fibrosis Bronchiectasis to Test How Well Different Doses of BI 1323495 Are Tolerated and How BI 1323495 Affects Biomarkers of Inflammation

This study is open to adults with non-cystic fibrosis bronchiectasis. The main purpose of this study is to find out how a medicine called BI 1323495 is tolerated by people with non-cystic

  • 0 views
  • 20 Jul, 2021
  • 4 locations
Validation of Patient Reported Outcome Measures in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex

- Bronchiectasis (QoL-B) and Patient-Reported Outcome Measurement Information System - Fatigue-Short Form (PROMIS F-SF 7a) in participants with newly diagnosed nontuberculous mycobacterial (NTM) lung infection

  • 0 views
  • 02 Aug, 2021
  • 129 locations
Reduction of Corticosteroid Use in Outpatient Treatment of Exacerbated COPD

all patients with a CRP 50mg/l, COPD and known diagnosis of bronchiectasis, as well as patients presenting with all three of the following symptoms: change of baseline dyspnea, change of sputum

corticosteroids
bronchiectasis
cough
forced expiratory volume
prednisone
  • 5 views
  • 01 Aug, 2021
  • 1 location
Natural History of Bronchiectasis

Background Bronchiectasis is a disease characterized by airways that are inflamed, abnormally dilated, and chronically infected. Individuals with bronchiectasis

respiratory infections
lung disease
allergic bronchopulmonary aspergillosis
respiratory symptom
cystic fibrosis
  • 489 views
  • 19 Jul, 2021
  • 1 location
NIAID Centralized Sequencing Protocol

Background Genetic testing called "sequencing" helps researchers look at DNA. Genes are made of DNA and are the instructions for our bodies to function. We all have thousands of genes. DNA variants are differences in genes between two people. We all have lots of variants. Most are harmless and some …

cancer
  • 54 views
  • 28 Jul, 2021
  • 2 locations
Natural History Management and Genetics of the Hyperimmunoglobulin E Recurrent Infection Syndrome (HIES)

critical to our complete understanding of bone metabolism, bronchiectasis, dental maturation, and atherosclerosis. Bi-allelic mutations in DOCK8 cause a combined immunodeficiency previously described as

immunodeficiency
cancer
eczema
deficiency
malignancy
  • 87 views
  • 01 Aug, 2021
  • 1 location
The C3I COVID-19 Project

This cohort study will obtain electronic health record (EHR) de-identified data from 21 health systems affiliated with the Cancer Center Cessation Initiative (C3I) network or health systems with large numbers of COVID-19 patients to explore whether smoking status, cancer history, and other risk factors among patients diagnosed with COVID-19 are …

cancer
primary cancer
  • 10 views
  • 31 Jul, 2021
  • 1 location
Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity

hypoventilation
bronchiectasis
mechanical ventilation
respiratory failure
pro-brain natriuretic peptide
  • 0 views
  • 31 Jul, 2021
  • 1 location