Collagen Vascular Diseases Clinical Trials

A listing of Collagen Vascular Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 46 clinical trials
Dupilumab in the Treatment of Keloids

This study is a prospective, randomized, double blind, placebo-controlled clinical trial. The study will include a total of 44 subjects with clinically measurable keloid lesions. At least 50% of subjects (at least 22 out of the 44 subjects) will also have documented diagnosis of concomitant type 2 atopic/allergic) inflammatory diseases. …

  • 10 Aug, 2021
  • 1 location
Compressive Device to Prevent Kelo d Scars Recurrence [SCARWARS]

SCARWARS study deals with the first on-human evaluation of a compressive device dedicated to the prevention of kelod scars recurrence after surgery. The tested device is made with clinical grade silicon. SCARWARS is a monocentric study. 27 patients will be include and follow during one year. The primary outcome of …

reconstructive surgery
  • 06 Aug, 2021
  • 2 locations
Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids

Keloids affect upto 16% of Africans causing significant cosmetic, functional and psychosocial distress. Available treatment options are associated with high recurrence and highly variable symptom relief. Autologous adipose derived stem-cells(ADSCs) have been described to have a potential therapeutic benefit in treating keloids. Investigators will compare intra-lesion single dose Autologous Adipose …

  • 28 Jun, 2021
  • 2 locations
A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

This is a 78-week (approximately a year and a half) open-label extension study of Beremagene Geperpavec (B-VEC), for participants aged 6 months and older, who have been diagnosed with Dystrophic Epidermolysis Bullosa (DEB). Participants will be dosed weekly with the topical B-VEC therapy. The primary endpoint will be to assess …

dystrophic epidermolysis bullosa
  • 19 Jun, 2021
  • 6 locations
Study of Sparsentan Treatment in Pediatrics With Proteinuric Glomerular Diseases

To evaluate the safety, efficacy and tolerability of sparsentan oral suspension and assess changes in proteinuria after once-daily dosing over the 108-week treatment period.

kidney biopsy
glomerular filtration rate
  • 19 Sep, 2021
  • 2 locations
Alport Syndrome Treatments and Outcomes Registry

ASTOR's primary purpose is to enroll families and patients with a history of Alport syndrome in a central registry. The information we gather will be used as a basis for studies designed to test potential treatments for Alport syndrome. ASTOR also aims to provide patients, families and physicians with the …

  • 28 Mar, 2021
  • 1 location
Epidemiology Study of Keloid

Although keloid is a very common condition; there are no statistics as to its true incidence and prevalence, neither in United States, nor elsewhere in the world. This trial intends to capture epidemiological data about this disease in a large population sample.

  • 21 Jan, 2021
  • 1 location
Genetic Analysis of Keloids

Keloids have a strong genetic component. The goal of this study is to identify genes and regulatory elements on chromosomes that are the cause for keloids or contribute to keloid scarring.

  • 27 Jan, 2021
  • 1 location
Web Based Investigation of Natural History of Keloid Disorder an Online Survey

This trial intends to gather very basic clinical information about keloid, its patterns of presentation, family history, ethnic background and correlation with the type of keloid, as well as prior treatment results that patients have had received.

  • 21 Jan, 2021
  • 1 location
Retrospective Study of Keloid Disorder

Purpose of this retrospective study is to review and analyze the information and data that has been already been generated during the course of routine practice of medicine by the investigators from 2007 up until Sept 1, 2016 from keloid patients who have sought medical care or medical advice for …

  • 21 Jan, 2021
  • 2 locations