Collagen Vascular Diseases Clinical Trials

A listing of Collagen Vascular Diseases medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 34 clinical trials
Evaluation of the Effect of Custom Compression Garments on Standing Static Balance in Ehlers Danlos Syndrome (EDS)

Studies have shown the existence of a proprioceptive deficit in patients with Ehlers Danlos Syndrome (EDS) (genetic pathology of connective tissue with hypermobility, multifactor joint instability). A study dating from 2010 showed a qualitative improvement in disability when wearing compression garments (CG) in this pathology, particularly in the fields of …

  • 17 Jun, 2022
  • 1 location
Rigosertib for RDEB-SCC

Epidermolysis bullosa (EB) is a heritable skin disease characterized by marked fragility of epithelialized tissue with blistering in skin and mucous membranes following the slightest mechanical trauma. Eighty percent of all patients suffering from recessive dystrophic EB (RDEB), a subtype originating from mutations in the COL7A1 gene, develop squamous cell …

dermatological disease
growth factor
cytotoxic chemotherapy
  • 03 Mar, 2022
  • 1 location
Cryospray Therapy Versus Standard of Care for Benign Airway Stenosis (CryoStasis)

Benign central airway stenosis (BCAS) is an important cause of both pulmonary morbidity and mortality. Notable causes include post-intubation stenosis, collagen vascular diseases, airway trauma

  • 22 Apr, 2022
  • 1 location
Complex Aortic Aneurysm Repair Using Physician Modified Endografts and Custom Made Devices (CARPE-CMD)

The purpose of this study is to evaluate the safety and efficacy of custom made devices, Zenith t-Branch devices and physician modification of FDA approved off-the-shelf endovascular grafts in the treatment of patients with complex abdominal aneurysms, aortoiliac aneurysms, thoracoabdominal aneurysms and aortic arch aneurysms who (1) have anatomy not …

  • 25 Mar, 2022
  • 1 location
Two Point Discrimination (TPD)

SPECIFIC AIMS Pain in both youth and adults is a complex, subjective and personal experience, and remains poorly understood. One particularly perplexing dimension of some forms of pain is the tendency of pain to spread outside of an affected body site to adjacent location, and then to unaffected body sites. …

pain disorder
two-point discrimination
back pain
chronic pain
  • 14 Feb, 2022
  • 1 location
Compressive Device to Prevent Kelo d Scars Recurrence [SCARWARS]

SCARWARS study deals with the first on-human evaluation of a compressive device dedicated to the prevention of kelod scars recurrence after surgery. The tested device is made with clinical grade silicon. SCARWARS is a monocentric study. 27 patients will be include and follow during one year. The primary outcome of …

reconstructive surgery
  • 06 Aug, 2021
  • 2 locations
Efficacy of Adipose Derived Stromal Vascular Fraction in the Treatment of Keloids

Keloids affect upto 16% of Africans causing significant cosmetic, functional and psychosocial distress. Available treatment options are associated with high recurrence and highly variable symptom relief. Autologous adipose derived stem-cells(ADSCs) have been described to have a potential therapeutic benefit in treating keloids. Investigators will compare intra-lesion single dose Autologous Adipose …

  • 28 Jun, 2021
  • 2 locations
A Long-term Treatment With B-VEC for Dystrophic Epidermolysis Bullosa

This is a 78-week (approximately a year and a half) open-label extension study of Beremagene Geperpavec (B-VEC), for participants aged 6 months and older, who have been diagnosed with Dystrophic Epidermolysis Bullosa (DEB). Participants will be dosed weekly with the topical B-VEC therapy. The primary endpoint will be to assess …

dystrophic epidermolysis bullosa
  • 19 Jun, 2021
  • 6 locations
Alport Syndrome Treatments and Outcomes Registry (ASTOR)

ASTOR's primary purpose is to enroll families and patients with a history of Alport syndrome in a central registry. The information we gather will be used as a basis for studies designed to test potential treatments for Alport syndrome. ASTOR also aims to provide patients, families and physicians with the …

  • 27 Apr, 2022
  • 1 location
BBD Longitudinal Study of Osteogenesis Imperfecta

Osteogenesis Imperfecta (OI) is a rare disorder of increased bone fragility characterized by fractures with minimal or absent trauma, dentinogenesis imperfecta (DI), and, in adult years, hearing loss. It is seen in both genders and all races. The clinical features of OI represent a continuum varying from perinatal lethality to …

type i collagen
bone disease
hearing loss
  • 26 Mar, 2022
  • 12 locations