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Ankylosing Spondylitis Clinical Trials

A listing of Ankylosing Spondylitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (54) clinical trials

Adalimumab in Alleviating Inflammation in Patients With Axial Spondyloarthritis

Axial spondyloarthritis is an inflammatory rheumatic disease mainly affecting joints in the spine and the sacroiliac joints. Inflammatory pathways are likely the central link from axial spondyloarthritis to the known increased risk of atherosclerotic morbidity. Positron emission tomography (PET) is the most sensitive method to detect inflammatory foci in clinical ...

Phase

Ankylosing Spondylitis and Antiphospholipid Antibodies

Methods Experimental design: longitudinal study prospective in a single center. The Ankylosing Spondylitis Assesment Study (ASAS) criteria are: (1) age <45 years, back pain 3 months, sacroiliitis on imaging and 1 associated minor criterion, or (2) HLA B27 positive and 2 minor criteria. Minor criteria are: inflammatory back pain, arthritis, ...

Phase N/A

AL-2 MP-1 (Polyimide) Acetabular Liner

The procedure involves removal of the diseased parts of the joint, that is the damaged cartilage and adjacent bone, and replacing them with artificial parts which closely resemble in structure and/or function the removed native parts. The artificial parts fit onto the reshaped bone and are fixed either with bone ...

Phase N/A

Assessment of SpondyloArthritis Society (ASAS) Classification and Diagnostic Criteria for Early Axial Spondyloarthritis (SpA)

Background: Existing criteria for AS/SpA such as mod. New York, ESSG, or Amor criteria for classification and/or diagnosis of spondyloarthritis have limitations when applied to early disease. Moreover, MRI is not part of any of the established criteria and the precise role of MRI in early axial disease has not ...

Phase N/A

OTIS Autoimmune Diseases in Pregnancy Project

- The primary objective of the study is to evaluate the effect of certain medications used in the first trimester of pregnancy with respect to major structural birth defects of newborns. - The secondary objectives of the study are to evaluate the effects of certain medications when used in the ...

Phase N/A

Health-Related Quality of Life and Disease-Related Costs: Comparison Between Ankylosing Spondylitis Rheumatoid Arthritis and Systemic Lupus Erythematosus in Taiwan

Ankylosing spondylitis (AS), rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are the most common rheumatic diseases dealt with rheumatologists in Taiwan. In previous studies, the 3 diseases all have broad impacts on health-related quality of life of patients and drive enormous economic burden on patients and society. The objective ...

Phase N/A

Examination of Radiographic Progression Efficacy and Safety of Long-Term Treatment With Infliximab in Patients With Ankylosing Spondylitis

Ankylosing spondylitis (AS) is a chronic inflammatory disease of unknown etiology that involves the sacroiliac joints, axial skeleton, entheses and peripheral joints. Chronic inflammation of entheses leads to new bone formation, syndesmophytes and ankylosis of joints, primarily in the axial skeleton. This leads to a dramatic loss of range of ...

Phase N/A

Pilot Open Label Clinical Trial With Abatacept in Ankylosing Spondylitis

Clinical manifestations and prevalence of ankylosing spondylitisAnkylosing spondylitis (AS) is a chronic inflammatory disease which affects primarily the spine and the sacroiliac joints, but extraspinal structures such as peripheral joints, the enthesis (insertion of tendons/ligaments at bone), the eye (uveitis) and the aorta can also be involved. There is a ...

Phase

Prednisolone in Active Ankylosing Spondylitis (AS)

Treatment of inflammatory rheumatic conditions with glucocorticosteroids is a mainstay in therapy. In rheumatic diseases such as rheumatoid arthritis, systemic lupus erythematodes and polymyalgia rheumatica glucocorticosteroids show a prompt effect in regards of musculoskeletal symptoms. Ankylosing spondylitis (AS) is an inflammatory rheumatic disease mainly affecting the spine. However peripheral joints, ...

Phase

National Observational Study On The Use Of Inflectra An Infliximab Biosimilar In Real Life

National, prospective, multicentre observational study designed for eligible patients treated with Inflectra. Its objectives are to describe under real conditions of use, the profile of patients treated with Inflectra and the response to treatment.

Phase N/A