Rectal Disorders Clinical Trials

A listing of Rectal Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 212 clinical trials
Defecation Patterns in Constipated Patients

therapeutic modalities and reduce healthcare costs associated with anorectal disorders.

Accepts healthy volunteers
  • 0 views
  • 04 Oct, 2022
  • 1 location
Anal Manometry Examination in Patients With Ulcerative Colitis

such as hypersensitive, hyperactive, poorly compliant rectum, and hypotensive sphincter. If this is the case, early aggressive treatment of the disease is needed. Another important point in

remission
crohn's disease
loperamide
  • 0 views
  • 04 Oct, 2022
  • 1 location
Non-Operative Management and Early Response Assessment in Rectal Cancer (NOM-ERA)

The investigators' data from a phase I study of short course radiation therapy followed by chemotherapy showed 74% complete clinical response (cCR). Given the promising response rate, the investigators are evaluating short course radiation therapy (SCRT) followed by chemotherapy in a multi-institution phase II trial to validate the cCR rate …

  • 0 views
  • 07 Oct, 2022
  • 4 locations
Understanding Mechanisms of Normal and Disordered Defecation

Researchers are trying to better understand why constipation occurs and improve the tests for diagnosing these conditions.

Accepts healthy volunteers
evacuations
chronic constipation
  • 92 views
  • 15 Oct, 2022
  • 1 location
A Clinical Investigation Evaluating Peristeen® Performance (CP342)

Peristeen has been on the market globally since 2006 and marketed in the US since 2012, and more than 10,000 patients worldwide have been using Peristeen, with over 3,000 patients in the US. However, the US reimbursement is not uniform, resulting in many patients suffering from NBD in sub-optimal bowel …

  • 0 views
  • 04 Oct, 2022
  • 1 location
Screening More Patients for Colorectal Cancer Through Adapting and Refining Targeted Evidence-Based Interventions in Rural Settings, SMARTER CRC (SMARTER CRC)

This study collects information to provide a model for how to rapidly adapt and scale-up multilevel interventions through clinic-health plan partnerships to reduce the burden of colorectal cancer (CRC) on the United states population. This study may improve colorectal cancer screening rates, follow-up colonoscopy, and referral to care in rural …

Accepts healthy volunteers
  • 0 views
  • 07 Oct, 2022
  • 1 location
S0820, Adenoma and Second Primary Prevention Trial (PACES)

The investigators hypothesize that the combination of eflornithine and sulindac will be effective in reducing a three-year event rate of adenomas and second primary colorectal cancers in patients previously treated for Stages 0 through III colon or rectal cancer.

anticoagulants
unstable angina
aspirin
adenoma
rectal carcinoma
  • 2953 views
  • 04 Oct, 2022
  • 408 locations
Scaling CRC Screening Through Outreach, Referral, and Engagement (SCORE) (SCORE)

This study will test the effectiveness of mailing fecal immunochemical tests (FITs) in increasing colorectal cancer (CRC) screening rates in U.S. adults ages 45-75. We are implementing this study in two age groups, 45-49 years and 50-75 years.

blood test
fecal immunochemical test
Accepts healthy volunteers
adenoma
  • 0 views
  • 07 Oct, 2022
  • 1 location
Comparative Effectiveness of Split-Dose Colonoscopy Bowel Preparation Regimens

From the patients' perspective, the most formidable part of the colonoscopy experience is the process of bowel cleansing. A poorly tolerated bowel preparation regimen often leads to incompletion of scheduled colonoscopies which in turn undermines the effectiveness of colonoscopy, increases cost, and decreases patient satisfaction. The current standard bowel preparation …

bowel preparation
  • 63 views
  • 13 Oct, 2022
  • 1 location
A Phase 2/3, Randomized, Open-Label Study of Maintenance GRT-C901/GRT-R902, A Neoantigen Vaccine, in Combination With Immune Checkpoint Blockade for Patients With Metastatic Colorectal Cancer

The primary objective of the Phase 2 portion of the study is to characterize the clinical activity of maintenance therapy with GRT-C901/GRT-R902 in combination with checkpoint inhibitors in addition to fluoropyrimidine/bevacizumab versus fluoropyrimidine/bevacizumab alone as assessed by changes in circulating tumor (ct)DNA. The primary objective of the Phase 3 portion …

  • 0 views
  • 24 Oct, 2022
  • 24 locations