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Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (23) clinical trials

UT Southwestern Diabetic Foot Ulcers (DFU) and Osteomyelitis (DFO) Recruitment Database Data and Tissue Repository

Subjects will be consented during a scheduled visit for standard care at the Clements University Hospital, UT Southwestern Wound Clinic, Parkland Hospital or the Parkland ASC Wound Clinic. There will be 2 study visits: Baseline and operating room visit. At the time of scheduled procedures or laboratory blood draws (as ...

Phase N/A

Biofilm Modified Macrophage Phenotype and Function in Diabetic Wound Healing

Specific Objective: Determine if functionally active macrophage isolated from biofilm-infected diabetic wounds show extra cellular matrix degrading phenotype causing wound collagen degradation Understand by investigating whether increased presence of ECM degrading wound macrophage phenotypes in biofilm infected human diabetic wounds are associated with reduced wound collagen levels and increased wound ...

Phase N/A

Study of Ceftazidime-Avibactam Blood Concentrations in Intensive Care Unit Patients With Renal Failure Requiring Continuous Dialysis

The study's primary objective is to determine plasma and dialysis fluid concentrations in patients prescribed ceftazidime-avibactam as the standard treatment for their infection and requiring continuous venovenous hemodiafiltration (CVVHDF) as part of the standard treatment for acute or chronic renal failure. Secondarily, the study will evaluate the pharmacokinetics of ceftazidime-avibactam ...

Phase N/A

Central Nervous System Infections in Denmark

The investigators include data on diagnosis at admission, symptoms and signs on admission, character and timing of diagnostic work-up and treatment and outcome assessed by the Glasgow Outcome Score (GOS). Diagnostic work-up and treatment is left at the discretion of the local physician and therefore not standardised In general any ...

Phase N/A

Acinetobacter Baumannii-related Osteomyelitis: Clinical and Epidemiological Characterization

INTRODUCTION Acinetobacter baumannii is an opportunist pathogen that has become increasingly important over recent years as a cause of nosocomial infections (1,2). Ventilator-associated pneumonia, central line-associated bloodstream infection and bone and soft tissue infection secondary to open fractures are among the conditions most associated with this agent. Attention is drawn ...

Phase N/A

Bacterial Infections in Cirrhotic Patients With Acute Severe Liver Injury

Acute hepatic insults including hepatitis flare-up, active alcohol assumption and hepatotoxic drug use are common in patients with cirrhosis especially in Eastern countries.These patients are at high risk of developing acute-on-chronic liver failure (ACLF) and associated with high short-term mortality. And the natural history of these patients is frequently complicated ...

Phase N/A

Cost of Off-label Antibiotics in Osteoarticular Infections

Due to the emergence of multidrug-resistant micro-organisms in patients with bone and joint infection (BJI), the prescription of off-labeled antibiotics seem to be more and more common as part of routine care. These new antibiotics are, however, more expensive, and there are no precise data in France regarding the volume ...

Phase N/A

Xydalba Utilization Registry in France

OBJECTIVES The objectives of this registry are as follows: To determine the following characteristics in patients who received intravenous Xydalba administration Patient characteristics. Disease characteristics. Pathogen characteristics. To characterize the usage of Xydalba. To characterize the patient's residence and, in hospitalized patients, the lengths of hospital and intensive care unit ...

Phase N/A

An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT

Ceftolozane-tazobactam has recently emerged as a highly valuable option for the management of severe Gram-negative infections including those caused by multi-drug resistant (MDR) organisms, demonstrating superior antibacterial activity against the pathogens most frequently causing serious infection in the critically ill, such as Pseudomonas aeruginosa and Enterobacteriaceae spp, when compared with ...

Phase N/A

Risk-factors for Multidrug-resistant Bacteria Colonization Among Patients at High Risk of STIs

The spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) bacteria have become a worldwide public health concern. Infection with MDR/XDR bacteria is associated with increased morbidity, increased risk of therapeutic failure and healthcare costs. The largest burden is from extended-spectrum betalactamase-producing enterobacteriaceae (ESBL) and carbapenem-resistant enterobacteriaceae (CRE). The World Health ...

Phase N/A