Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 667 clinical trials
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Comparative Study to Evaluate Efficacy and Safety of Gepotidacin to Nitrofurantoin in Treatment of Uncomplicated Urinary Tract Infection (UTI)

Urinary tract infections (UTIs; acute cystitis) are very common, with approximately 11 percentage of women (>18 years of age) reporting at least 1 episode of acute cystitis per year. The purpose of this study to evaluate the therapeutic response (combined microbiological and clinical efficacy per participant) of oral gepotidacin compared …

cystitis
nitrite
gepotidacin
acute cystitis
nitrofurantoin
  • 421 views
  • 28 Jan, 2021
  • 99 locations
None
A Study to Evaluate Efficacy and Safety of Gepotidacin in the Treatment of Uncomplicated Urinary Tract Infection (UTI)

This study will be conducted to evaluate the therapeutic response of oral gepotidacin compared to oral nitrofurantoin for uncomplicated UTI in adolescent and adult female subjects. In this study, subjects will be randomly assigned in a 1:1 ratio to receive either oral gepotidacin or oral nitrofurantoin. The study will enroll …

cystitis
nitrite
gepotidacin
acute cystitis
nitrofurantoin
  • 677 views
  • 05 Mar, 2021
  • 81 locations
None
Effects of Video-based Health Education on Maternal and Child Health in Ethiopia

Low adherence to recommended health and nutrition strategies during the critical 1000 day-window of opportunity is multifactorial but low quality communication is key limitation. Innovative strategies to improve interpersonal communication can reduce the burden and the fatigue of community health workers and may result in a greater change. The findings …

prenatal
bacterial vaginosis
fatigue
post-natal
  • 25 views
  • 27 Jan, 2021
  • 1 location
None
Prevention of Perinatal Sepsis (PoPS): Evaluation of Chlorhexidine Wipes of Birth Canal and Newborn

baby from bacterial infections after birth. If effective, this could be used as an inexpensive alternative to antibiotics to prevent newborn infections in resource-poor countries.

bacterial infections
antibiotics
bacterial infection
chlorhexidine
antibiotic therapy
  • 13 views
  • 07 Nov, 2020
  • 1 location
None
Bacteremia Antibiotic Length Actually Needed for Clinical Effectiveness

The World Health Organization, U.S. Centers for Disease Control and Prevention, Association of Medical Microbiology and Infectious Diseases (AMMI) Canada, and Health Canada have all declared antimicrobial resistance a global threat to health, based on rapidly increasing resistance rates and declining new drug development. Up to 30-50% of antibiotic use …

bloodstream infection
blood culture
critical illness
pneumonia
antibiotics
  • 4357 views
  • 01 Oct, 2021
  • 59 locations
None
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placebo in the prevention of the first invasive extraintestinal pathogenic Escherichia coli disease (IED) event caused by ExPEC9V O-serotypes.

Accepts healthy volunteers
  • 20 views
  • 02 Dec, 2021
  • 143 locations
None
Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit?

The objective of this trial is to determine whether certain subgroups of children with acute sinusitis exist in whom antibiotic therapy can be appropriately withheld.

rhinosinusitis
acute sinusitis
amoxicillin
amoxicillin-clavulanate
sinusitis
  • 229 views
  • 29 Oct, 2021
  • 7 locations
None
PCT Guided Stopping of Antibiotic Therapy in Children With Sepsis

The investigators' objective is to compare the risk of mortality and/or treatment failure in children admitted to the PICU with sepsis and managed by PCT guided therapy for stopping of antibiotics ('study' group) with those managed with 'standard practices' based on the evidence based guidelines ('control' group). Children with suspected …

systemic inflammatory response syndrome
antibiotics
antibiotic therapy
sepsis
inflammatory response
  • 0 views
  • 19 Jul, 2021
  • 1 location
None
Azithromycin-Prevention in Labor Use Study (A-PLUS)

Maternal and neonatal infections are among the most frequent causes of maternal and neonatal deaths, and current antibiotic strategies have not been effective in preventing many of these deaths. Recently, a randomized clinical trial conducted in a single site in The Gambia showed that treatment with oral dose of 2 …

antibiotics
septicemia
antibiotic therapy
neonatal infection
prenatal
  • 0 views
  • 26 Jan, 2021
  • 8 locations
None
Efficacy of Hydroxychloroquine Telmisartan and Azithromycin on the Survival of Hospitalized Elderly Patients With COVID-19

In November 2019, Wuhan city in China, became the center of an outbreak of pneumonia due to a novel coronavirus SARS-CoV-2, which disease was named coronavirus disease 2019 (COVID19) in February, 2020. The COVID19 is much more dangerous for people over 60 with a death rate of 3.6% after 60, …

azithromycin
covid-19
diabetes
hydroxychloroquine
pneumonia
  • 0 views
  • 11 Sep, 2021
  • 1 location