Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 671 clinical trials
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Evaluating Newly Approved Drugs in Combination Regimens for Multidrug-Resistant TB With Fluoroquinolone Resistance (endTB-Q)

endTB-Q Clinical Trial is a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of two new, all-oral, shortened regimens for multidrug-resistant tuberculosis (MDR-TB) with fluoroquinolone resistance.

pulmonary tuberculosis
clofazimine
fluoroquinolones
linezolid pill
bedaquiline 100 mg
  • 94 views
  • 17 Sep, 2021
  • 10 locations
None
PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)

Data regarding optimal treatment for extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae blood-stream infection are lacking. Observational studies show conflicting results when comparing treatment with combination beta-lactam-beta-lactamase inhibitor and carbapenems. The investigators aim to evaluate the effect of definitive treatment with meropenem vs. piperacillin-tazobactam on the outcome of patients with bacteremia due …

blood culture
carbapenem
beta-lactamase inhibitor
bacteremia
meropenem
  • 23 views
  • 28 Oct, 2021
  • 2 locations
None
Study to Optimize the Use of New Antibiotics

Quasi-experimental intervention multicenter trial of patients treated with new antibiotics (before-after study). The study will be carried out in 14 hospitals of the Andalusian Public Health System with representation from all the provinces and has been designed in two phases: A first phase in which an observational study of historical …

dalbavancin
carbapenem
bacteremia
ceftazidime
vancomycin
  • 3 views
  • 24 Jan, 2021
  • 20 locations
None
The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract

Malaria in pregnancy has devastating consequences for mother and foetus. WHO recommends intermittent preventive treatment in pregnancy (IPTp) with sulphadoxine-pyrimethamine (SP) for asymptomatic women, but high-level parasite resistance to SP threatens its efficacy. Dihydroartemisinin-piperaquine (DP) has the potential to replace SP for IPTp. However, the DP strategy has not been …

premature birth
sulphonamide
sexually transmitted disease
metronidazole
antibacterial
  • 0 views
  • 29 Sep, 2021
  • 1 location
None
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children Known or Suspected to be Caused by Susceptible Gram-positive Organisms Including MRSA

To determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

streptococcal toxic shock syndrome
tenderness
erosion
absolute neutrophil count
abscess
  • 0 views
  • 26 Nov, 2021
  • 122 locations
None
Phase III Clinical Trial of a Candidate PCV13 in Healthy People Aged 6 Weeks and Above (PICTPCV13i)

Streptococcus pneumoniae is a major cause of morbidity and mortality in children worldwide, resulting in up to 1 million pediatric deaths every year.Since the licensure of PCV7 and PCV13,the reported overall decline in invasive pneumococcal disease in hospitalized children younger than 5 years several years is approximately 60% in Western …

vaccination
conjugate vaccine
pneumococcal vaccine
pneumococcal
polysaccharide
  • 0 views
  • 12 Aug, 2021
  • 1 location
None
Safety Tolerability and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Patients

or confirmed aerobic Gram-negative bacterial infections and after multiple-dose administration in hospitalized pediatric patients 3 months to < 18 years of age with suspected or confirmed

antibiotics
pneumonia
renal function
  • 3 views
  • 07 Aug, 2021
  • 21 locations
None
Safety Tolerability Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)

suspected gram-negative bacterial infection. Participants are expected to require hospitalization through completion of intravenous (IV) study intervention, and have at least one of the following primary

  • 55 views
  • 20 Oct, 2021
  • 66 locations
None
Safety Tolerability and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Patients

; 18 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the pharmacokinetics (PK) of cefiderocol after single-dose administration of cefiderocol in

renal function
cefiderocol
bacterial infection
sepsis
antibiotics
  • 7 views
  • 20 Oct, 2021
  • 21 locations
None
DACC in the REduction of Surgical Site INfection

Surgical site infection is an infection at a place in the body where surgery has taken place, and has been reported in around 5% of people undergoing an operation. In vascular surgery, infection rates are as high as 30%. Methods to reduce this rate of infection should be investigated thoroughly …

vascular surgery
surgical site infection
vascular surgery procedure
wound infection
site infection
  • 5 views
  • 17 Nov, 2021
  • 1 location