Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 667 clinical trials
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Role of Probiotics in the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients: A Randomized Placebo Control Trial

Cirrhotic patients are predisposed to bacterial infection. A large proportion of which is spontaneous bacterial peritonitis(SBP), which are mainly caused by enteric bacteria.SBP in a

spontaneous bacterial peritonitis
cirrhosis
norfloxacin
bacterial resistance
ascites
  • 6 views
  • 07 Nov, 2020
  • 1 location
None
2- Day vs. 5- Day Terlipressin and Ceftriaxone in the Control Acute Gastroesophageal Variceal Hemorrhage

The use of prophylactic antibiotics in cirrhotics with gastrointestinal bleeding has been a routine clinical practice . It is still unknown whether use of short term vasoconstrictors and antibiotics could have superior acute hemostatic rate. Thus, the investigators conducted a trial to compare the effectiveness between participants receiving terlipressin and …

  • 0 views
  • 23 Jan, 2021
  • 1 location
None
Randomised Open Label Trial of Hypertonic Saline and Carbocisteine in Bronchiectasis (CLEAR)

Patients with bronchiectasis (BE) suffer from a persistent cough, daily sputum expectoration, recurrent chest infections, and a poor health-related quality of life. Current guidelines for the management of BE highlight the lack of evidence to recommend mucoactive agents, such as hypertonic saline (HTS) and carbocisteine, to aid sputum-removal as part …

  • 0 views
  • 23 Jan, 2021
  • 11 locations
None
A Procalcitonin-based Algorithm in Adhesion-related Small Bowel Obstruction

Adhesion-related small bowel obstruction is a common digestive emergency that can be managed either conservatively or surgically. However, the choice between these two approaches can be difficult due to the absence of specific signs. The objective of this study is to evaluate the clinical impact of a procalcitonin-based algorithm.

  • 0 views
  • 29 Jul, 2021
  • 1 location
None
Sputum Microbiota and the Association With Clinical Parameters in Steady-state Acute Exacerbation and Convalescence of Bronchiectasis

Study 1 is a cross-sectional investigation. Patients with clinically stable bronchiectasis (symptoms, including cough frequency, sputum volume and purulence, within normal daily variations) will undergo baseline assessment consisting of history taking, routine sputum culture, 16srRNA pyrosequencing, measurement of sputum inflammatory markers, oxidative stress biomarkers and MMPs, and spirometry. Microbiota taxa …

spirometry
cough
sputum culture
antibiotics
grip
  • 27 views
  • 23 Jan, 2021
  • 1 location
None
Connection Between Periodontitis and Exudative Age-related Macular Degeneration

Aqueous flare is increased in different kind of inflammations of eye. This is caused by disruption of blood-aqueous-barrier. The investigators assume that low grade systemic inflammation, such as periodontitis, increase aqueous flare and possibly activates exudative age-related macular degeneration.

anti-infective
  • 22 views
  • 26 Jan, 2021
  • 1 location
None
Preventing Young Infant Infections Using Azithromycin in Labour (PreYIAL) Trial

A trial to assess cumulative incidence of skin and soft tissue infections (SSTI) in infants (by three months of age) born to mothers receiving a single-dose of 2 grams of oral azithromycin during labour (or immediately prior to delivery in the case of caesarean section), compared to infants whose mothers …

antibiotics
  • 2 views
  • 24 Jan, 2021
  • 1 location
None
Treatment of Bacterial Vaginosis Prior to Active Labor and Infectious Morbidity

Bacterial vaginosis (BV) is the most common cause of vaginal discharge among repro-ductive aged women. It is been linked to adverse maternal and neonatal outcomes. Our objective is to evaluate if the use of a single dose of metronidazole in women with BV at time of delivery reduces infectious morbidities

vaginal discharge
metronidazole
repro
oral metronidazole
bacterial vaginosis
  • 10 views
  • 08 Aug, 2021
  • 2 locations
None
PredictEndTB Signature for Individualizing Treatment in Multidrug-Resistant Tuberculosis

PredictEndTB signature is a non-inferiority, prospective, parallel-group open-label randomized controlled trial evaluating the efficacy of individualised antituberculous treatment durations that utilize the transcriptomic signature-based model compared to the standardised twenty months treatment in a cohort of multidrug-resistant tuberculosis patients.

  • 0 views
  • 14 Apr, 2021
  • 5 locations
None
Evaluating Newly Approved Drugs for Multidrug-resistant TB

endTB Clinical Trial a Phase III, randomized, controlled, open-label, non-inferiority, multi-country trial evaluating the efficacy and safety of five new, all-oral, shortened regimens for multidrug-resistant tuberculosis (MDR-TB).

fluoroquinolones
pulmonary tuberculosis
moxifloxacin
pyrazinamide
vasectomy
  • 223 views
  • 20 Sep, 2021
  • 11 locations