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Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (48) clinical trials

Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care

The purpose of this study is to characterize the PK ( Pharmacokinetics) of understudied drugs administered to children per standard of care as prescribed by their treating caregiver. This will be accomplished by the collection of biological samples during the time of drug administration per standard of care as prescribed ...

Phase N/A

Clindamycin-rifampin Drug Interaction in the Treatment of Bone and Joint Infections

Treatment of bone and joint infections remains difficult and variable according to centres and countries. Clindamycin given intravenously and followed by an oral route is recommended for the treatment of staphylococcal, streptococcal and anaerobes bone and joint infections by the French Society for Infectious Diseases. For staphylococcal bone and implant ...

Phase N/A

French National Observatory on Infective Endocarditis

All the clinical, biological, microbiological and laboratory describing the history of patients and their evolution during hospitalization for infective endocarditis will be obtained from physicians supporting patients and recorded in an electronic case report form. Will include collected clinical characteristics (site, pre-existing heart disease underlying symptoms, complications), biological characteristics (dosage ...

Phase N/A

Neonatal Bacterial Meningitis Cohort

In this study, we aimed to develop a clinical risk score model, according to the available clinical syndromes and commonly laboratory tests, for screening BM among full-term neonates in a large-scale retrospective cohort, and prospectively validated the risk score in multicenter cohort.

Phase N/A

Clinical Metagenomics of Infective Endocarditis

Background and Rationale Infective endocarditis (IE) is an infection of cardiac valves. IE mainly involves bacteria, more rarely fungi. IE is an uncommon diseases with an estimated incidence of 1-12 cases per 100,000 inhabitants per year. The diagnostic of IE relies on the collection of biological samples (blood cultures and ...

Phase N/A

Impact of Clinical Care Pathway on Prognosis and Therapeutic Medical Care of Infective Endocarditis

Infective endocarditis (IE) is defined as a bacterial infection of the endocardium (inner surface of the heart), which may include one or more heart valves. Epidemiologic pattern has changed during the last 20 years whereas the incidence was unchanged. However, the mortality increase despite recent diagnosis and therapeutic advances. Only ...

Phase N/A

Fever and Shivering: Frequency and Role in Predicting Serious Bacterial Infection

Background: Fever is a common complaint and lacking localizing signs poses a diagnostic dilemma, mostly, but not only, in children under 3 years of age. Recent years studies found common clinical markers for a Serious Bacterial Infection (SBI) to be ineffective in confirming or ruling out a suspected SBI in ...

Phase N/A

Surveillance of Hospitalised Pneumonia and Bacterial Meningitis in T ne District Togo 2010-2013

The aim of this study is to estimate the burden of disease due to pneumococci, other bacteria and viruses in the African meningitis belt prior to pneumococcal conjugate vaccine introduction and to estimate the population impact of the vaccine after its implementation in 2014. In a defined population of a ...

Phase N/A

Rapid Test for Detection of the Focus of Infection in Post Neurosurgical Patients.

Hepatocyte growth factor (HGF) is local acute phase protein with regenerative properties that become biologic inactive during chronic inflammation and loses the binding affinity to glycosaminoglycan in the extracellular ma-trix. HGF is excreted into the gastrointestinal tract and is not detected in normal urine. Nosocomial meningitis can occur when brain ...

Phase N/A

Study of Tigecycline Pharmacokinetics in Patients Undergoing Continuous Renal Replacement Therapy(CRRT)

The aim of this study is to determine the Pharmacokinetics/Pharmacodynamics(PK/PD) of tigecycline in critical ill patients undergoing continuous renal replacement therapyCRRTand examine whether the dosage needs adjustment. The study will observe two groups of patients respectively and compare the difference between them. Patients who need to receive CRRT when treat ...

Phase N/A