Bacterial Infections Clinical Trials

A listing of Bacterial Infections medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 65 clinical trials
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Evaluation of Pharmacokinetics Safety and Tolerability of Ceftazidime-avibactam in Neonates and Infants.

This study will assess the pharmacokinetics, safety, and tolerability of single and multiple doses of intravenous ceftazidime-avibactam in hospitalized infants and neonates from 26 weeks gestation to 3 months of age. In Part A of the study all patients will receive a single dose of ceftazidime-avibactam. In Part B all …

  • 0 views
  • 24 Oct, 2021
  • 59 locations
None
PipEracillin Tazobactam Versus mERoPENem for Treatment of Bloodstream Infections Caused by Cephalosporin-resistant Enterobacteriaceae (PETERPEN)

Data regarding optimal treatment for extended-spectrum beta-lactamase (ESBL) producing Enterobacteriaceae blood-stream infection are lacking. Observational studies show conflicting results when comparing treatment with combination beta-lactam-beta-lactamase inhibitor and carbapenems. The investigators aim to evaluate the effect of definitive treatment with meropenem vs. piperacillin-tazobactam on the outcome of patients with bacteremia due …

blood culture
beta-lactamase inhibitor
piperacillin-tazobactam
beta-lactam
ceftriaxone
  • 23 views
  • 24 Oct, 2021
  • 2 locations
None
Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections in Children Known or Suspected to be Caused by Susceptible Gram-positive Organisms Including MRSA

To determine the safety and descriptive efficacy of dalbavancin for the treatment of acute bacterial skin and skin structure infections in children, aged birth to 17 years (inclusive), known or suspected to be caused by susceptible Gram-positive organisms, including methicillin-resistant strains of Staphylococcus aureus.

methicillin
wound infection
ABSSI
vancomycin
metabolic acidosis
  • 0 views
  • 17 Oct, 2021
  • 96 locations
None
Safety Tolerability Efficacy and Pharmacokinetics of Imipenem/Cilastatin/Relebactam (MK-7655A) in Pediatric Participants With Gram-negative Bacterial Infection (MK-7655A-021)

suspected gram-negative bacterial infection. Participants are expected to require hospitalization through completion of intravenous (IV) study intervention, and have at least one of the following primary

  • 55 views
  • 20 Oct, 2021
  • 66 locations
None
Safety Tolerability and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Patients

; 18 years of age with suspected or confirmed aerobic Gram-negative bacterial infections To assess the pharmacokinetics (PK) of cefiderocol after single-dose administration of cefiderocol in

antibiotic therapy
renal function
bacterial infection
cefiderocol
pneumonia
  • 7 views
  • 20 Oct, 2021
  • 21 locations
None
A Study of Vaccination With 9-valent Extraintestinal Pathogenic Escherichia Coli Vaccine (ExPEC9V) in the Prevention of Invasive Extraintestinal Pathogenic Escherichia Coli Disease in Adults Aged 60 Years And Older With a History of Urinary Tract Infection in the Past 2 Years

The purpose of this study is to demonstrate the efficacy of 9-valent extraintestinal pathogenic Escherichia coli vaccine (ExPEC9V) compared to placebo in the prevention of the first invasive extraintestinal pathogenic Escherichia coli disease (IED) event caused by ExPEC9V O-serotypes.

Accepts healthy volunteers
  • 20 views
  • 24 Oct, 2021
  • 139 locations
None
Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit?

The objective of this trial is to determine whether certain subgroups of children with acute sinusitis exist in whom antibiotic therapy can be appropriately withheld.

amoxicillin-clavulanate
antibiotic therapy
sinusitis
amoxicillin-clavulanic acid
acute sinusitis
  • 229 views
  • 26 Oct, 2021
  • 7 locations
None
Suppression Of Bacterial Vaginosis (BV) [SUBVert]

A Phase II randomized, double-blind, placebo-controlled study screening approximately 600 adult females, aged 18-55, with a goal to enroll approximately 250 participants to achieve 200 evaluable participants at the test of cure (TOC) visit. The study is designed to determine the clinical efficacy of an investigational product (IP), TOL-463 Insert, …

antibacterial
pap smear
anti-infectives
oral metronidazole
bacterial vaginosis
  • 235 views
  • 24 Oct, 2021
  • 5 locations
None
Multi-Gyn ActiGel Plus for Treatment of Bacterial Vaginosis

This is a randomized, double-blind, placebo-controlled clinical investigation. The objective of the study is to confirm the efficacy of Multi-Gyn ActiGel Plus to treat BV as compared to a placebo control. Treatment arm 1: Multi-Gyn ActiGel Plus Treatment arm 2: placebo gel Both the Multi-Gyn ActiGel Plus and the placebo …

bacterial vaginosis
  • 3 views
  • 24 Oct, 2021
  • 1 location
None
Temocillin vs Meropenem for the Targeted Treatment of Bacteraemia Resistant to Third Gen Cephalosporins

A Phase 3, Multicenter, Randomised, Controlled, Open-Label Study to demonstrate noninferiority of temocillin (unauthorized investigational medicinal product IMP in Spain, but authorized in Belgium and UK) vs a carbapenem antibiotic (meropenem) in adults with bacteraemia due to third-generation cephalosporin-resistant Enterobacteriaceae. The duration of treatment will be between 7 and 14 …

cephalosporins
carbapenem
antibiotics
ceftriaxone
meropenem
  • 0 views
  • 20 Oct, 2021
  • 32 locations