Heart Attack (Myocardial Infarction) Clinical Trials

1. Background 1.1. Antiplatelet therapy after acute myocardial infarction Dual antiplatelet therapy with aspirin, combined with a P2Y12 receptor inhibitor, is a cornerstone of therapy for acute myocardial infarction (AMI). Treatment with clopidogrel in addition to aspirin resulted in a 20% reduction in major adverse cardiovascular events (MACE) when compared ...

Phase 3 Multi-Center, Double-Blind, Randomized, Placebo-Controlled, Parallel Group Evaluation of the Efficacy, Safety, and Tolerability of a Research Medication in Reducing the Occurrence of Major Cardiovascular Events

The THEMIS clinical research study is evaluating a study drug to see if it may help prevent heart attack and stroke in people with type 2 diabetes.

Announcing a new research study of nutritional supplements Specifically, the study will examine whether certain supplements can reduce readmission rates in adults >65 years of age who are hospitalized for the following diagnoses: Heart attack Heart failure COPD Pneumonia

People with these conditions have a higher risk of heart attack or stroke in the future. Because we know who is at a greater risk, we want to take early steps to try to prevent a cardiovascular emergency. The Aleprevent clinical research study will look at whether an investigational medication ...

Have you been told that you have or that you are at risk for developing Heart Disease? If you are 45 years of age or older and have high triglyceride levels, you may be eligible to participate in a clinical research study evaluating the safety and effectiveness of an investigational ...

The treatment options this study will compare are: (1) Hybrid Coronary Revascularization [HCR] (a combination of surgery and catheter procedures to open up clogged heart arteries) and (2) Percutaneous Coronary Intervention [PCI] (catheter procedures alone to open up clogged heart arteries). There are no new or "experimental" procedures being tested ...

Damage to the heart caused by a myocardial infarction (heart attack) occurs most often during the early morning hours (6AM). Thus, the involvement of the circadian system (circa= approximately day) has been suggested. The circadian system in humans or animals is based on the rotation of the earth with day ...

The overarching purpose of SATISFY-SOS is to implement a rigorous process to assess short-term and intermediate-term outcomes of surgical and procedural patients who receive anesthesia services at Barnes-Jewish Hospital facilities, located in St. Louis, Missouri. Specifically, patients will be followed for major morbidity events, for mortality, and for quality of ...

The primary aim of the study is to detect and evaluate new cardiac biomarkers, evaluate and improve acute coronary syndrome (ACS) risk scores, which takes into account clinical, gender specific, psycho-social and lifestyle-risk factors, protein patterns and genetic variability in addition to the classical risk factors with respect to the ...