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Aneurysm Clinical Trials

A listing of Aneurysm medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (97) clinical trials

Clinical Study of Thoracic Aortic Aneurysm Exclusion

A vascular aneurysm is a permanent, localized dilatation of a blood vessel at least 1 1/2 to 2 times the normal vessel diameter. The aorta is the most frequent site for aneurysms, with approximately 10% of aortic aneurysms located above the renal arteries in the thoracic segment. Thoracic aortic aneurysms ...

Phase N/A

Endovascular Exclusion of TAAA/AAA Utilizing Fenestrated/Branched Stent Grafts

The purpose of the study is to evaluate the role of fenestrated/branched stent-grafts in the exclusion of abdominal aortic and thoracoabdominal aneurysms. The evaluation shall be conducted with subjects that would be expected to have great difficulty tolerating open surgical repair and anatomies not suitable for devices currently marketed.

Phase N/A

Endovascular Exclusion of Abdominal Aortic Aneurysms in High Risk Patients

This study is a prospective, non-randomized evaluation of endovascular aneurysm repair in high-risk patients. The purpose of this study is to determine whether this endovascular prosthesis is safe and effective for the intended use of treating AAA/iliac aneurysm in patients who are at high risk for standard aneurysm surgical repair. ...

Phase N/A

Endovascular Exclusion of Ascending and Thoracic Aortic Pathology

This study is a prospective, non-randomized evaluation of ascending and thoracic pathology endovascular repair in the high-risk patient. The purpose of this study is to assess the role of the thoracic aortic pathology treatment using endovascular prosthesis in high-risk patients. The study objectives include (1) to assess the safety and ...

Phase N/A

PET/CT Imaging of Aneurysm Wall Inflammation

Rationale: Aneurysm development, progression and rupture are characterised by extensive inflammation, dominated by the infiltration of T-cells, B-cells and macrophages. Recent studies into the pathophysiology of aneurysm wall degradation suggest a close relation between increased mechanical stress and the local activation of infiltrated lymphocytes and macrophages. The non-invasive detection of ...

Phase N/A

Randomized Preventive Vascular Screening Trial of 65-74 Year Old Men in the Central Region of Denmark

Well-documented health benefits may be achieved through prophylactic screening for cardiovascular disease. The advantages are fewer premature deaths and a reduction in the number of hospital admissions and amputations. Furthermore, hospitals will benefit from the derived reduction in the pressure on surgery and intensive care capacities at vascular surgery departments. ...


The Use of Nesiritide in Thoracic Aneurysm Repair to Prevent Acute Renal Failure

Acute renal failure is a major and serious complication of more than 200,000 cardiovascular surgeries performed on adult Americans annually (www.sts.org). The incidence of acute renal failure (ARF) after cardiac surgery (depending on criteria used to define ARF) is 1-5%, in the absence of preexisting renal dysfunction. The subset of ...


Evaluation of Safety and Efficacy of the Bifurcated Multilayer Flow Modulator (BMFM ).

Endovascular approaches to TAAAs have evolved during the past decade. The initial experiences with fenestrated and branched endografts have shown that total endovascular repair is effective and may reduce morbidity rates in patients with arch, thoracoabdominal and pararenal aneurysms. The Cleveland Clinic group has recently reported on their updated clinical ...

Phase N/A

Zenith Alpha Abdominal Endovascular Graft

The purpose of this study is to evaluate the clinical performance of the Zenith Alpha™ Abdominal Endovascular Graft for the treatment of abdominal aortic or aorto-iliac aneurysm.

Phase N/A

Repair of Thoracoabdominal Aortic Aneurysms

Patients diagnosed with TAAA have a poor medical history and require surgical intervention to extend life. Several repair techniques have been developed, but each carry risk. Open repairs are durable but have substantial perioperative mortality and postoperative morbidity. Endovascular techniques are plagued by high procedural complexity and poor branch vessel ...

Phase N/A