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Kidney Failure (Pediatric) Clinical Trials

A listing of Kidney Failure (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (4) clinical trials

A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment

This Phase 1, multi-center, study will enroll patients with renal insufficiency. Single ascending doses of setmelanotide will be evaluated, in semi-sequential group design. The following four cohorts of patients will be evaluated: Cohort A: setmelanotide in subjects with mild renal insufficiency Cohort B: setmelanotide in subjects with moderate renal insufficiency …


A Study of Pevonedistat in Combination With Azacitidine in Participants With Higher-risk Myelodysplastic Syndromes (HR MDS) Chronic Myelomonocytic Leukemia (CMML) or Acute Myelogenous Leukemia (AML) With Severe Renal Impairment or Mild Hepatic Impairment

The drug being tested in this study is called pevonedistat. The study will characterize the PK of pevonedistat, assess the safety, and determine the dose of pevonedistat, in combination with azacitidine, in participants with myelodysplastic syndromes (MDS), CMML and AML who also have severe renal impairment or mild hepatic impairment. …


RUCONEST as a Therapeutic Strategy to Reduce the Incidence of Delayed Graft Function

This is a randomized, single-center double blinded study. The main objective of this study are to determine the ability of rhC1INH to reduce the incidence and severity of delayed graft function in comparison to placebo in recipients of kidneys after cardio-circulatory determination of death (DCD). This trial has specifically been …


Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

This is a single center, open-label dose-escalating study assessing safety, tolerability, dosing effect, and early signals of efficacy of intra-arterially delivered autologous (from self) adipose tissue-derived mesenchymal stem/stromal cells (MSC) in 30 patients with progressive diabetic kidney disease (DKD). DKD will be defined as chronic kidney disease (CKD; estimated glomerular …