Kidney Failure (Pediatric) Clinical Trials

A listing of Kidney Failure (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
Patient-Derived Stem Cell Therapy for Diabetic Kidney Disease

The Researchers will assess the safety, tolerability, dosing effect, and early signals of efficacy of intra-arterially delivered autologous (from self) adipose (fat) tissue-derived mesenchymal stem/stromal cells (MSC) in patients with progressive diabetic kidney disease (DKD).

diabetic nephropathy
diabetes
renal failure
nephropathy
hypertension
  • 85 views
  • 17 Feb, 2022
  • 1 location
Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions (PiCASO)

The purpose of this study is to test the efficacy of a peer support coaching intervention to improve activated chronic illness self-management versus an attention control group in 225 adolescents and young adults with childhood onset chronic conditions.

peer support
adult care
chronic disease
chronic illness
  • 31 views
  • 04 Oct, 2022
  • 1 location
ENCOMPASS: Expansion Study B RCT

Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources. Patient navigation programs may help those with complex health conditions to improve their care and outcomes. Community health navigators (CHNs) are community members who help guide patients through …

congestive heart failure
systolic blood pressure
diabetes
COPD
glomerular filtration rate
  • 0 views
  • 06 Oct, 2021
  • 1 location
ENCOMPASS: Expansion Study A, RCT (ENCOMPASS)

Some patients living with multiple long-term health conditions have difficulty accessing the services they need, despite available primary care and community resources. Patient navigation programs may help those with complex health conditions to improve their care and outcomes. Community health navigators (CHNs) are community members who help guide patients through …

congestive heart failure
systolic blood pressure
diabetes
COPD
glomerular filtration rate
  • 1 views
  • 06 Jun, 2022
  • 1 location
Evaluation of a Renin Inhibitor, Aliskiren, Compared to Enalapril, in C3 Glomerulopathy

The aim of this cross-over trial is to assess aliskiren, a direct renin inhibitor, as a novel treatment to block complement activation in the kidneys and thereby attenuate renal disease and stabilize or improve kidney function and compare it to the currently used treatment with the angiotensin converting enzyme inhibitor, …

enzyme inhibitor
mammogram
kidney biopsy
  • 17 views
  • 22 Mar, 2022
  • 1 location
Impact of Low Protein Diet Supplemented With Ketoanalogues Supplementation on Uremic Toxins Production

Chronic kidney disease (CKD) is associated with accumulation of uremic toxins like p-cresyl sulfate and indoxyl sulfate that are associated of cardiovascular complication and perturbation of glucose metabolism. These toxins are produced by fermentation of protein by intestinal microbiota but the role of low protein diet and ketoanalogue supplementation on …

dialysis
glomerular filtration rate
  • 0 views
  • 15 Jul, 2021
  • 1 location
Safety and Efficacy of HA380 Hemoadsorption in Patients With Septic Shock

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Intensive care unit (ICU) mortality in patients with septic shock and acute kidney injury (AKI) requiring continuous renal replacement therapy (CRRT) remains high and approximates 50-60%. Sepsis is the leading etiology for AKI and CRRT …

hemodiafiltration
renal replacement therapy
  • 0 views
  • 20 Aug, 2021
  • 1 location
Evaluating the Implementation of Evidence-Based Kidney Nutrition Practice Guidelines: The AUGmeNt Study Protocol

Evidence-Based Nutrition Practice Guidelines (EBNPGs) inform registered dietitian nutritionist (RDN) care for patients with chronic kidney disease grade 5 treated by dialysis (CKD G5D); however, there has been little evaluation of best practices for implementing EBNPGs. In this effectiveness-implementation hybrid study with a quasi-experimental design, United States RDNs in hemodialysis …

dialysis
  • 0 views
  • 12 Sep, 2021
  • 1 location
Dapagliflozin in Non-diabetic Stage IV CKD

As chronic kidney disease (CKD) continues to increase worldwide, along with the demand for related life-saving therapies, the financial burden of CKD will place an increasing drain on health care systems. Experimental studies showed that glomerular capillary hypertension and impaired sieving function with consequent protein overload play a pathogenic role …

hemoglobin a1c
diabetes
  • 0 views
  • 08 Dec, 2021
  • 1 location
Does High-dose Vitamin B3 Supplementation Prevent Major Adverse Kidney Events During Septic Shock?

Sepsis is the most common cause of acute kidney injury (AKI) in critically ill patients and is associated with a high mortality rate. Currently there is no available specific treatment to prevent or treat AKI in this setting. Many experimental and clinical data suggest that Nicotinamide, a safe and inexpensive …

vasopressor
  • 0 views
  • 29 Jul, 2021
  • 1 location