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Kidney Failure (Pediatric) Clinical Trials

A listing of Kidney Failure (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (151) clinical trials

Plasmalyte Versus Saline in Trauma Patients

Fluid resuscitation remains the cornerstone for the care of severe trauma patients to compensate for blood loss, to compensate for capillary leak induced by systemic inflammation but also to prevent the detrimental consequences of traumatic rhabdomyolysis. Isotonic saline (NaCl 0.9%), called "physiological serum" is the standard fluid for the resuscitation …


Collection of Samples From Pregnant Women for the Evaluation of Preeclampsia (Pre-E) Biomarkers

Eligible subjects will provide written informed consent after which demographic and baseline clinical data will be recorded. Collection of whole blood and urine samples will be performed at one or more clinic visits from pregnant women carrying a single fetus with no known fetal abnormalities. Interim study visits will continue …

Phase N/A

Rural Home Hospital: Proof of Concept

Home hospital care is hospital-level care at home for acutely ill patients. In multiple publications mostly in urban environments, home hospital care delivered cost-effective, high-quality, excellent experience care with similar quality and safety as traditional hospital care. Most home hospital models deliver care in urban environments, not in rural environments. …

Phase N/A

Exercise in Patients With End Stage Kidney Disease

This study will be conducted over a 3 year time period. This is a trial of an exercise intervention vs. standard of care in patients receiving chronic dialysis. The specific aims will be to determine feasibility of patient recruitment, adherence to the exercise program, and efficacy of the intervention on …

Phase N/A

Evaluate the Safety Tolerability and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus

This study consists of both single and multiple ascending doses in healthy subjects and in subjects with cholestatic or uremic pruritus. Up to 48 healthy subjects will receive a single dose of EP547 or placebo. There will be a screening period of up to 28 days prior to the first …


Automated Peritoneal Dialysis Versus Intermittent Hemodialysis in Acute Kidney Injury

The incidence of acute kidney injury (AKI) is rapidly increasing worldwide. This is a common and devastating disorder, especially in critical illnesses, affecting 5-8% of all hospitalized patients and up to 30% of those in intensive care units, with high mortality. About 50-80% critical patients with AKI needed dialysis treatment. …

Phase N/A

MySlainte: Testing the Effect of Involving Partners in a CVD Prevention Community Lifestyle Program

The prevalence of chronic diseases in Ireland is increasing and places significant burden both on the individual and family unit, but also on an already overstretched healthcare system. Many chronic diseases are preventable and frequently share common risk factor and unhealthy lifestyle profiles; which offers a unique opportunity to intervene, …

Phase N/A

Renal Outcome in Patients With COVID-19

Beginning in December 2019, a novel coronavirus, designated as severe acute respiratory distress coronavirus 2 (SARS-CoV-2), has caused an international outbreak of respiratory illness termed coronavirus disease 2019 (COVID-19). Although the clinical manifestations of COVID-19 are dominated by respiratory symptoms, some patients show severe kidney abnormalities. Acute kidney injury (AKI) …

Phase N/A

Comparison of Biphozyl and Phoxilium as a Replacement Fluid During CVVH for AKI in Adults and Their Effects on pH- Bicarbonate-levels and Respiratory Situation

After being fully eligible by meeting all inclusion and none of the exclusion criteria, participants will be randomly assigned to one of two groups, either the Phoxilium - Group or Biphozyl - Group. After randomization, patients receive either Phoxilium or Biphozyl for CVVH initiation and maintenance as a replacement fluid …


The Effect of Three Endourological Procedures for the Management of Renal Calculi Regarding Acute Kidney Injury

This is a 3-arm parallel group prospective randomized active-treatment clinical study. A total of 75 patients with renal calculi 10-30 mm in maximal diameter measured in abdominal CT scan will be recruited in this research protocol. Patient enrollment will be performed from patients referred to Urolithiasis Unit of the 1st …

Phase N/A