Idiopathic Membranous Nephropathy Clinical Trials

A listing of Idiopathic Membranous Nephropathy medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 19 clinical trials
A Phase III Randomized, Open-Label Active Comparator-Controlled Multicenter Study to Evaluate Efficacy and Safety of Obinutuzumab in Patients With Primary Membranous Nephropathy

This study will evaluate the efficacy, safety, pharmacodynamics, and pharmacokinetics (PK) of obinutuzumab compared with tacrolimus in participants with primary membranous nephropathy (pMN).

  • 5 views
  • 20 Oct, 2022
  • 57 locations
A Clinical Study of MIL62 in Primary Membranous Nephropathy

, to evaluate the efficacy of MIL62 and cyclosporine in the treatment of primary membranous nephropathy. Eligible subjects in both phases received treatment and follow-up for a total of 104 weeks. The

  • 0 views
  • 16 Jun, 2022
  • 1 location
Evaluate the Efficacy and Safety of SHR1459 Tablets in Patients With Primary Membranous Nephropathy

The purpose of this study is to evaluate the efficacy and safety of SHR1459 tablets in patients with primary membranous nephropathy.

  • 0 views
  • 04 Oct, 2022
  • 15 locations
Different Immunosuppressive Treatment in iMN

The primary objective of this study is to compare the 24 month remission of different immunosuppressive therapies in the treatment of idiopathic membranous nephropathy (iMN)

  • 2 views
  • 30 Apr, 2022
  • 1 location
A Randomized, Open-label, Two Arm, Parallel Group, Proof-of-concept Clinical Trial to Investigate the Efficacy and Safety of LNP023 Compared With Rituximab in the Treatment of Subjects With Idiopathic Membranous Nephropathy

membranous nephropathy (MN) who are at high risk of disease progression defined on the basis of antibody anti-PLA2R titre and proteinuria.

lnp023
rituximab
kidney biopsy
diuretics
proteinuria
  • 30 views
  • 20 Oct, 2022
  • 32 locations
Personalized Medicine for Membranous Nephropathy (PMMN)

Membranous Nephropathy with nephrotic syndrome and anti-PLA2R1 (phospholipase A2 receptor 1) antibodies GEMRITUX protocol: 6 months of symptomatic antihypertensive and

nephrotic syndrome
angiotensin
diuretics
antihypertensive
rituximab
  • 49 views
  • 27 Feb, 2022
  • 2 locations
In Vitro Immunomodulation in Membranous Nephropathy Relapses (BIOGEM)

In order to propose the best therapeutic option to relapsed MN patients with strong activation of the Th17 pathway, the investigators propose to study in vitro the effect of different immunomodulators on the Th17/Treg balance, assessed by cytokine profile and lymphocyte phenotyping using flow cytometry.

remission
nephropathy
proteinuria
  • 0 views
  • 11 Jul, 2022
  • 1 location
Efficacy and Safety of VB119 in Subjects With Membranous Nephropathy

This study is a Phase 1b/2a, open-label, sequential-cohort, dose escalation, and dose expansion study to evaluate the safety, tolerability, PK, and PD of VB119 in subjects with primary MN

nephropathy
proteinuria
kidney biopsy
follicle stimulating hormone
treatment regimen
  • 6 views
  • 04 Oct, 2022
  • 16 locations
Rituximab Combined With Cyclosporine Versus Rituximab Alone in the Treatment of iMN

The primary objective of this study is to determine whether or not cyclosporine (CsA) combined with RTX is more effective than RTX alone in the treatment of idiopathic membranous nephropathy

  • 0 views
  • 24 May, 2021
  • 7 locations
Efficacy of Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy (ITN080AI) (REBOOT)

participants with PM. Background Primary membranous nephropathy (MN) is among the most common causes of nephrotic syndrome in adults. MN affects individuals of all ages

monoclonal antibody
nephrotic syndrome
kidney biopsy
arthritis
monoclonal antibodies
  • 340 views
  • 13 Oct, 2022
  • 11 locations