Cancer (Pediatric) Clinical Trials

A listing of Cancer (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 209 clinical trials
Pilot Study of Laser Interstitial Thermal Therapy Followed By Hypofractionated Radiation Therapy for Treatment of Recurrent Gliomas. (GCCC 19140)

The purpose of this study is to evaluate the treatment regimen of using Laser Interstitial Thermal Therapy (LITT) and Hypo-fractionated Radiation Therapy to treat patients with recurrent gliomas.

brain mri
treatment regimen
MRI
karnofsky performance status
recurrent tumor
  • 2 views
  • 28 Oct, 2022
  • 3 locations
Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

This research study is studying an immunotherapy drug (pembrolizumab or KEYTRUDA) as a possible treatment for pediatric hepatocellular carcinoma or hepatocellular neoplasm not otherwise specified (HCN NOS).

measurable disease
platelet count
hepatocellular carcinoma
cancer
pediatric hepatocellular carcinoma
  • 0 views
  • 07 Oct, 2022
  • 3 locations
DECT in Imaging Patients With Solid Organ Cancer With Intracranial Metastasis

This trial studies how well dual energy computed tomography (DECT) works in imaging patients with solid organ cancer that has spread to the brain. Imaging techniques, such as DECT, may help find and diagnose tumor cells and find out how far the tumor cells have spread in the brain.

primary cancer
metastasis
  • 0 views
  • 04 Oct, 2022
  • 1 location
ACTengine® IMA203/IMA203CD8 as Monotherapy or in Combination With Nivolumab in Recurrent and/or Refractory Solid Tumors (ACTengine)

The study purpose is to establish the safety and tolerability of IMA203 product with or without combination with nivolumab in patients with solid tumors that express preferentially expressed antigen in melanoma (PRAME).

primary cancer
measurable disease
metastatic solid tumor
neuropathy
solid tumour
  • 0 views
  • 04 Oct, 2022
  • 7 locations
Phase I Trial of the Combination of Bortezomib and Clofarabine in Adults With Refractory Solid Tumors, Lymphomas, or Myelodysplastic Syndromes

Background Researchers want to develop better ways to treat cancer. In this study, they will give people with cancer two drugs. These drugs have been used on their own to treat some blood cell cancers. Objectives To test the safety and efficacy of the drug combination of bortezomib and clofarabine. …

advanced cancer
primary cancer
clofarabine
neuropathy
solid tumour
  • 25 views
  • 28 Oct, 2022
  • 1 location
The Role of Stereo-tActic BoDy RadIotherApy iN Oligo-Progressive MalignanT Disease (RADIANT)

Systemic therapy is the main treatment for patients with metastatic cancers. Oligo-progression has become a recognized entity for metastatic cancer and it is thought that a subset of cancer cells may develop heterogeneity and resistant clones while receiving systemic therapy. This results in overall tumor response but progression in metastatic …

primary cancer
metastasis
carcinoma
docetaxel
breast cancer
  • 0 views
  • 24 Oct, 2022
  • 1 location
Evaluation of the Effectiveness and Implementation of the BETTER Women Peer Health Coaching Program

The Building on Existing Tools To improvE cancer and chronic disease pRevention and screening in primary care (BETTER) Program allows patients in primary care to have a dedicated visit with a prevention practitioner to discuss chronic disease prevention and cancer screening. A prevention practitioner is a health professional, working in …

primary cancer
Accepts healthy volunteers
  • 1 views
  • 04 Oct, 2022
  • 3 locations
Use of a Pre-Surgical Toolkit in Improving Surgical Care and Outcomes in Older Participants With Cancer

This trial studies how well the use of a pre-surgical toolkit (OPTI-Surg) works in improving surgical care and outcomes in older participants with cancer. In many elderly patients, surgery can greatly affect physical condition and the ability to return to pre-surgery levels of physical functioning. Providing pre-surgical recommendations may help …

primary cancer
metastasis
cancer
lung lobectomy
cancer diagnosis
  • 7 views
  • 04 Oct, 2022
  • 35 locations
A Phase II Study of Split-Dose R-CHOP in Older Adults With Diffuse Large B-cell Lymphoma

This study is investigating a new administration schedule of Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, Prednisone (R-CHOP) chemotherapy for participants with Diffuse Large B-Cell Lymphoma (DLBCL), focusing on an underserved elderly population (aged 75 and up; certain participants 70-74 may be eligible) that is often excluded from clinical trials. Participants can expect …

lymphoma
antibiotics
pet/ct scan
bone marrow procedure
  • 2 views
  • 21 Oct, 2022
  • 1 location
An Open-Label, Phase 2 Efficacy Study of Temozolomide (TMZ) In Advanced Succinate Dehydrogenase (SDH)-Mutant/Deficient Gastrointestinal Stromal Tumor (GIST)

Funding Source - FDA OOPD FDA-approved products for patients with unresectable or metastatic GIST include therapies such as imatinib and sunitinib. Although there are FDA-approved products for the treatment of advanced/metastatic GIST, these therapies are known to be ineffective in the SDH-mutant/deficient subtype and no known effective therapies exist. The …

primary cancer
renal function test
sunitinib
temozolomide
cancer
  • 11 views
  • 27 Oct, 2022
  • 4 locations