Cancer (Pediatric) Clinical Trials

A listing of Cancer (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 118 clinical trials
A Study to Evaluate the Safety Pharmacokinetics Pharmacodynamics and Clinical Activity of JNJ-63723283 an Anti-PD-1 Monoclonal Antibody in Participants With Advanced Cancers

The Primary purpose of this study is to identify the recommended Phase 2 dose [RP2D(s)] for JNJ-63723283 in Part 1, to assess the anti-tumor activity of JNJ-63723283 at the RP2D(s) in participants with selected advanced cancers including non-small-cell lung cancer (NSCLC), melanoma, renal, bladder, small-cell lung cancer (SCLC), gastric/esophageal cancer, …

monoclonal antibodies
primary cancer
lung cancer
  • 48 views
  • 22 Jul, 2021
  • 35 locations
Game-Based Physical Activity in Childhood Cancer Survivors

This study will test whether a game-based exercise plan can help increase the level of physical activity in childhood cancer survivors. The game-based exercise plan will involve participation by

  • 0 views
  • 24 Jul, 2021
  • 1 location
Per-operating Use of a Probe for Detection of +

The objective of the study is to evaluate the sensibility of the probe Forimtech to detect + emission in vivo in humans and its usefulness during elective surgical procedure Hypothesis:The probe Forimtech is able to allow per-surgery detection of tumoral lesions sensible to 18F-FDG and to help in the realization …

pet/ct scan
  • 0 views
  • 01 Aug, 2021
  • 1 location
SurvivorLink: Scalability of an Electronic Personal Health Record

, for pediatric cancer survivors and their caregivers. The researchers will develop a standardized intervention and training for the SurvivorLink trial, followed by conducting a Hybrid Type 1

  • 0 views
  • 02 Aug, 2021
  • 11 locations
A Safety and Efficacy Study of CC-90011 in Combination With Nivolumab in Subjects With Advanced Cancers

This is a Phase 2, multicenter, open-label, multi-cohort study to assess safety and efficacy of CC-90011 in combination with nivolumab in subjects with small cell lung cancer or squamous non-small cell lung cancer who have progressed after 1 or 2 lines of therapies. The primary objectives of the study are …

neutrophil count
measurable disease
primary cancer
gilbert's syndrome
liver metastasis
  • 0 views
  • 19 Jul, 2021
  • 42 locations
[177Lu]-NeoB in Patients With Advanced Solid Tumors and With [68Ga]-NeoB Lesion Uptake

First in Human study to characterize the safety, tolerability, pharmacokinetics (PK), distribution, radiation dosimetry, and anti-tumor activity of [177Lu]-NeoB in patients with advanced solid tumors known to overexpress GRPR and with [68Ga]-NeoB lesion uptake.

solid neoplasm
measurable disease
primary cancer
pet/ct scan
breast cancer
  • 8 views
  • 02 Aug, 2021
  • 10 locations
Platform Trial of Novel Regimens Versus Standard of Care (SoC) in Non-small Cell Lung Cancer (NSCLC)

This study will compare the clinical activity of novel regimens (in combination or as single agents) to standard of care in participants with relapsed/refractory advanced NSCLC. The study will be conducted in two parts; Part 1 is an optional, non-randomized part based on safety and pharmacokinetics/pharmacodynamics (PK/PD) evaluation intended to …

measurable disease
primary cancer
treatment regimen
BRAF
docetaxel
  • 63 views
  • 22 Jul, 2021
  • 66 locations
This Study Aims to Find and Test a Safe Dose of BI 905677 in Patients With Different Types of Cancer (Solid Tumours)

This study is open to adults with different types of advanced cancer (solid tumours). This study is open to people in whom previous treatments were not successful. The purpose of this study is to find out the highest dose of BI 905677 the participants can tolerate. BI 905677 is a …

growth factor
neutrophil count
advanced cancer
primary cancer
direct bilirubin
  • 16 views
  • 20 Jul, 2021
  • 5 locations
Study of MK-4830 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-4830-001)

This study has dose escalation (Part A, B, C) and dose expansion (Cohorts A-L) parts. Dose escalation is to evaluate the safety, tolerability, and preliminary efficacy of MK-4830 monotherapy administration (Parts A and B) and in combination with pembrolizumab (Part C). Dose expansion is to evaluate the objective response rate …

EGFR
growth factor
measurable disease
pemetrexed
metastatic solid tumor
  • 86 views
  • 02 Aug, 2021
  • 28 locations
BRAF V600E-mutant Colorectal Cancer Study of Encorafenib Taken With Cetuximab Plus or Minus Chemotherapy (BREAKWATER)

To evaluate whether encorafenib plus cetuximab (EC), alone or in combination with chemotherapy, can improve clinical outcomes relative to current standard of care chemotherapy in participants with previously untreated BRAF V600E-mutant mCRC

BRAF
primary cancer
bevacizumab
capecitabine
metastasis
  • 0 views
  • 22 Jul, 2021
  • 71 locations