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Cancer (Pediatric) Clinical Trials

A listing of Cancer (Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (17) clinical trials

A clinical trial sponsored by National Cancer Institute (NCI) for a research study for the treatment of Optic Nerve Glioma, von Recklinghausen's Disease, Plexiform Neurofibroma, Nerve Sheath Tumors, neurofibroma

BACKGROUND Neurofibromatosis Type 1 (NF1) is an autosomal dominant, progressive genetic disorder characterized by diverse clinical manifestations. Patients with NF1 have an increased risk of developing tumors of the central and peripheral nervous system including plexiform neurofibromas (PN), dermal neurofibromas, optic pathway tumors, brain tumors, malignant peripheral nerve sheath tumors ...

Phase N/A

Patients are needed to participate in a clinical research study evaluating Carboplatin, Vincristine, Bevacizumab, Irinotecan, Mebendazole, Temozolomide for the treatment of Diffuse Intrinsic Pontine Glioma, Pleomorphic Xanthoastrocytoma, Astrocytoma, Optic Nerve Glioma, gliosarcoma, Glioblastoma Multiforme, Brainstem Glioma, Low Grade Glioma, Pilomyxoid Astrocytoma, DIPG

This is a phase I/II study of mebendazole in combination with standard of care agents for pediatric patients with gliomas. Patients with low-grade gliomas will receive a regimen of mebendazole in combination with vincristine, carboplatin, and temozolomide. Patients with high-grade gliomas and diffuse intrinsic pontine gliomas will receive a regimen ...


A Phase 1 clinical study for patients with Glioma, Astrocytoma, Oligodendroglioma, gliosarcoma, Glioblastoma Multiforme, Anaplastic Oligoastrocytoma

PVSRIPO will be delivered intratumorally by CED using an intracerebral catheter placed within the enhancing portion of the tumor. The population group are patients with recurrent WHO grade III or IV malignant glioma who are aged 12 through 18 years old. After a single dose of PVSRIPO, subjects will return ...


Patients are needed to participate in a clinical research study for the treatment of childhood ALL, Lymphoma, leukemia

The GMALL registry serves the purpose of ALL research and quality assurance. The Registry collects data about diagnostics, treatment and outcome of Adult ALL Patients in the clinical routine, whether or not the patient is treated within a clinical trial.

Phase N/A

A clinical research study of Vemurafenib

PRIMARY OBJECTIVES: I. To determine the objective response rate (ORR; complete response + partial response) in pediatric patients treated with vemurafenib with advanced solid tumors (including central nervous system [CNS] tumors), lymphomas or histiocytic disorders that harbor activating BRAF V600 mutations. SECONDARY OBJECTIVES: I. To estimate the progression free survival ...


A clinical research study of rQNestin34.5v.2, Cyclophosphamide for the treatment of Astrocytoma, Oligodendroglioma, Pylocytic/Pylomyxoid Astrocytoma, Malignant Glioma of Brain, Ganglioglioma, Ependymoma, Anaplastic Oligodendroglioma of Brain (Diagnosis)

This research study is a Phase I clinical trial, which tests the safety of an investigational drug and also tries to define the appropriate dose of the investigational drug as a possible treatment for this diagnosis. "Investigational" means that the intervention is being studied. The FDA (the U.S. Food and ...


Patients are needed to participate in a clinical research study to evaluate Central Nervous System Neoplasms, Medulloblastoma

This is a Phase 2 multi-center, open-label, parallel-group study that will assess the efficacy, safety and tolerability of pomalidomide in children and young adults aged 1 to < 21 years with recurrent or progressive primary brain tumors after at least one prior standard therapy. The study will consist of 4 ...


Patients are needed to participate in a clinical research study of Anti-thymocyte globulin, Bone marrow transplant from a related donor, Tacrolimus

The induction of transplantation tolerance involves the specific elimination of the immune response to the transplant but not to other antigens. In the realm of kidney transplantation, tolerance means that the recipient is unable to detect the donor transplant kidney as foreign, and therefore the recipient is unable to reject ...

Phase N/A

A Phase 3 clinical study for patients using Mycophenolate mofetil, methotrexate, Methotrexate (low dose), tacrolimus

Study Design This is a prospective randomized trial to determine the effectiveness of different doses of GVHD prophylaxis on mucositis, engraftment and aGVHD. Study consists of two study groups of 50 subjects each. Group A will receive Tac and MTX (15 mg/m2 day +1, 10 mg/m2 day +3, +6, +11). ...