Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 230 clinical trials
Sleep Trial to Prevent Alzheimer's Disease (SToP-AD)

The purpose of this study is to determine if treatment with the sleep aid suvorexant can decrease the rate of amyloid-β (Aβ) accumulation in the brain.

amyloid
dementia
alzheimer's disease
Accepts healthy volunteers
  • 1 views
  • 04 Oct, 2022
  • 1 location
A Clinical Study of CD19/BCMA CAR-T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and Vasculitis

A Clinical Study on the Safety and Effectiveness of CD19/BCMA Chimeric Antigen Receptor T Cells in the Treatment of Refractory POEMS Syndrome, Amyloidosis, Autoimmune Hemolytic Anemia, and

vasculitis
cyclophosphamide
methotrexate
  • 0 views
  • 07 Mar, 2022
  • 1 location
Transdermal Trigeminal Electrical Neuromodulation on Mild Cognitive Impairment With Insomnia

structural connectivity as well as sleep parameters evidenced by polysomnography and sleep surveys, with consideration for amyloid positivity and brain-derived neurotrophic factor .

cognitive impairment
amyloid deposition
amyloid
mild cognitive impairment
polysomnography
  • 0 views
  • 23 Mar, 2022
  • 1 location
APG-2575 in Combination With Novel Therapeutic Regimens in Subjects With Relapsed or Refractory Multiple Myeloma

This is a Phase Ib/II, open-label, multi-center study evaluating the safety, tolerability, efficacy, and PK/ Pharmacodynamics of APG-2575 in combination with Pd/DRd in patients with relapsed/refractory (RR) multiple myeloma (MM). The study consists of dose escalation and dose expansion phases. The study consists of will start with 2 arms noted …

dexamethasone
measurable disease
amyloid deposition
refractory multiple myeloma
hysterectomy
  • 0 views
  • 07 Mar, 2022
  • 3 locations
Molecular and Structural Imaging in Atypical Alzheimer's Disease: A Longitudinal Study

This is a neuroimaging study designed to learn more about amyloid and tau burden in the brain of patients with Atypical Alzheimer's Disease and how burden may change over a one year period.

  • 2 views
  • 01 May, 2022
  • 1 location
Citalopram as a Posterior Cortical Protective Therapy in Parkinson Disease

This Parkinson disease (PD) trial will test whether 26 months of citalopram, compared to placebo, can alter the build-up of toxic amyloid-beta plaques in the visuospatial cortex of the brain

cognitive impairment
dopamine
  • 0 views
  • 19 Apr, 2022
  • 1 location
Nutritional Intervention With the Dietary Supplement, Immunocal® in MCI Patients: Promotion of Brain Health

Alzheimer disease (AD) is a dementing illness characterized by progressive neuronal degeneration, gliosis, and the accumulation of intracellular inclusions and extracellular deposits of amyloid

  • 20 views
  • 27 Feb, 2022
  • 1 location
Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Breast Cancer

amount of abnormal protein (called beta-amyloid) in the brain that is a marker of Alzheimer's disease pathology. One of the most common complaints among breast cancer survivors is cognitive or

taxane
  • 0 views
  • 13 Jun, 2022
  • 1 location
Biodistribution of [11C]Acetoacetate/[18F]Fluorodeoxyglucose in Subjects With Risk Factors for Alzheimer's Disease (AcAc PET)

Amyloid Transformation in AD (BEAT-AD) Study protocol. This cohort of patients will receive a maximum of 3 [11C]Acetoacetate (AcAc)/[18F]Fluorodeoxyglucose (FDG) PET scans over 18 weeks as part of this

positron emission tomography
amyloid
alzheimer's disease
amyloidosis
Accepts healthy volunteers
  • 0 views
  • 26 Mar, 2022
  • 1 location
The Synapse Project

to collect longitudinal amyloid, tau, and Synaptic vesicle glycoprotein 2A (SV2A) positron emission tomography (PET) in participants in the Wisconsin Alzheimer's Disease Research Center (ADRC) and

dementia
positron emission tomography
Accepts healthy volunteers
cognitive impairment
alzheimer's disease
  • 2 views
  • 18 May, 2022
  • 1 location