Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 230 clinical trials
carDIo-ttranSSfOrm nucLEar Imaging Study (DISSOLvE)

The investigators will evaluate the change in myocardial uptake of 99m-technetium pyrophosphate (Tc-99m PYP) tracer on serial planar and SPECT imaging in patients enrolled in the CARDIO-TTRansform clinical trial (NCT04136171).

  • 0 views
  • 16 Mar, 2022
  • 1 location
Prevalence of Wild-Type Transthyretin Cardiac Amyloidosis Among Patients Undergoing Carpal Tunnel Release Surgery - A Prospective Study

Patients above the age of 60 will be recruited at their carpal tunnel release surgery. Biopsies will be taken from the wrist and examined for the presence of amyloid protein. A amyloid-positive

  • 0 views
  • 15 Oct, 2021
  • 1 location
Assessment of Safety, Tolerability, and Efficacy Measured by Amyloid Reduction of LY3372993 in Early Symptomatic Alzheimer's Disease

The reason for this study is to collect safety and efficacy information regarding the study drug remternetug in participants with early Alzheimer's disease (AD).

alzheimer's disease
mini-mental state examination
amyloid
  • 28 views
  • 20 Oct, 2022
  • 75 locations
A Phase 1/1a Study of Venetoclax, MLN9708 (Ixazomib Citrate) and Dexamethasone for Relapsed/Refractory Light Chain Amyloidosis

This phase I/Ia trial finds the best dose and side effects of venetoclax given in combination with ixazomib citrate and dexamethasone in treating patients with light chain amyloidosis that has

  • 0 views
  • 16 Oct, 2022
  • 3 locations
Study of the Safety and Efficacy of STI-6129 in Patients With Relapsed or Refractory Systemic AL Amyloidosis

assessing the safety, preliminary efficacy and pharmacokinetics of this anti-CD38-Duostatin 5.2 antibody-drug conjugate (ADC) for the treatment of relapsed or refractory systemic AL amyloidosis. The

  • 0 views
  • 07 Oct, 2022
  • 4 locations
Impact of Intensive Treatment of Systolic Blood Pressure on Brain Perfusion, Amyloid, and Tau in Older Adults (IPAT Study) (IPAT)

., excessive brain amyloid and tau protein deposition) in older adults at high risk for memory decline or dementia.

angiotensin
angiotensin ii
losartan
calcium
systolic blood pressure
  • 0 views
  • 25 Oct, 2022
  • 1 location
MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAA

-visible enlarged perivascular space and CAA, (2) Determine whether vascular amyloid clearance in CAA is associated with lymphatic drainage system, (3) Establish longitudinal data for MRI-visible enlarged

MRI
amyloid deposition
  • 3 views
  • 26 Jan, 2021
  • 1 location
UAB Alzheimer's Disease Center Core Cohort - Imaging Substudy (PiB ADC)

The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic amyloid deposition using the PET tracer [C-11]PiB in participants in the UAB

alzheimer's disease
amyloidosis
amyloid
Accepts healthy volunteers
cognitive assessment
  • 20 views
  • 15 Jun, 2022
  • 1 location
The Influence of Vascular Burden, Amyloid Plaque and Tau Protein in Patients With Vascular Cognitive Impairment and Dementia With Tauopathy

Background and objects Amyloid plaques and tau protein are the landmarks of neurodegeneration in Alzheimer's disease (AD). On the other hand, it is reported that cerebral ischemia may induce

Accepts healthy volunteers
  • 0 views
  • 02 Mar, 2022
  • 1 location
Predictive Value of Biomarkers of the Alzheimer's Disease (AD) in Elderly Patients With New-onset Epilepsy (BIOMALEPSIE)

hyperexcitability and amyloid deposits is bidirectional, the amyloid protein has a pro-seizure effect and the presence of epilepsy increases the amyloid deposits, (iv) in these models, the administration of an

antiepileptics
neuropsychological test
seizure
  • 3 views
  • 24 Feb, 2022
  • 1 location