Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 246 clinical trials
Brain iron, amyloid, and Alzheimer's disease

The goal of this study is to determine how levels of iron in the brain can affect proteins associated with Alzheimer’s disease, including amyloid.

amyloid
  • 0 views
  • 03 Mar, 2022
  • 1 location
Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab

remission (CR) rates in relapsed/refractory amyloidosis than historical pomalidomide/dexamethasone treatment.

daratumumab
combination therapy
dexamethasone
neutrophil count
platelet count
  • 0 views
  • 14 Jun, 2022
  • 4 locations
carDIo-ttranSSfOrm nucLEar Imaging Study (DISSOLvE)

The investigators will evaluate the change in myocardial uptake of 99m-technetium pyrophosphate (Tc-99m PYP) tracer on serial planar and SPECT imaging in patients enrolled in the CARDIO-TTRansform clinical trial (NCT04136171).

  • 0 views
  • 16 Mar, 2022
  • 1 location
MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAA

-visible enlarged perivascular space and CAA, (2) Determine whether vascular amyloid clearance in CAA is associated with lymphatic drainage system, (3) Establish longitudinal data for MRI-visible enlarged

amyloid deposition
MRI
  • 3 views
  • 26 Jan, 2021
  • 1 location
Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment

increased amyloid plaque burden as a potential contributing factor to the cognitive deficits and complaints seen in patients experiencing CICI. The novel feature of this project is in the combined use of

immunostimulant
adjuvant chemotherapy
  • 1 views
  • 25 Mar, 2022
  • 1 location
Gamma Induction for Amyloid Clearance in Alzheimer's Disease

Alzheimer's Disease (AD) is characterized by amyloid-β (Aβ) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration. Amyloid-β and tau are proteins

amyloid
dementia
memory impairment
mental state examination
brain stimulation
  • 23 views
  • 23 Oct, 2022
  • 1 location
Brain Energy for Amyloid Transformation in Alzheimer's Disease Study (BEAT-AD)

The Brain Energy for Amyloid Transformation in AD (Alzheimer's disease) or BEAT-AD study will compare the effects of a ketogenic low-carbohydrate diet and a low-fat diet in adults with mild

amyloidosis
cognitive impairment
cognitive assessment
alzheimer's disease
amyloid
  • 10 views
  • 14 Jun, 2022
  • 1 location
Prevalence of Transthyretin Cardiac Amyloidosis in Clinically Significant Aortic Stenosis

The purpose of this study is to determine the prevalence of transthyretin cardiac amyloidosis (TTR-CA) among patients with moderate and severe aortic stenosis in Southeast Minnesota using 99mTc

stenosis
  • 0 views
  • 07 Oct, 2022
  • 1 location
Amyloid-beta PET Imaging With 18F-92 in Alzheimer's Disease

Alzheimer's disease is a neurodegenerative disease. Numerous studies have reported that β-amyloid (Aβ) is an important marker for the diagnosis of AD. 18F-92 molecular probe is a novel

memory impairment
alzheimer's disease
amyloid
Accepts healthy volunteers
  • 0 views
  • 24 Jan, 2022
  • 1 location
A Safety Study of Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis

This phase I trial studies the side effects and best dose of daratumumab, ixazomib, and dexamethasone in treating participants with amyloid light chain amyloidosis. Monoclonal antibodies, such

  • 128 views
  • 18 Oct, 2022
  • 1 location