Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 246 clinical trials
Non-ischemic Preservation of the Donor Heart in Heart Transplantation

The study intends to compare standard ischemic cold static storage (ICSS) of retrieved hearts intended to be transplanted, to non-ischemic heart preservation (NIHP) in a randomized clinical multicentre trial. The primary hypothesis is that the non-ischemic hypothermic cardioplegic preservation (NIHP) is safe and superior to ischemic cold static storage (ICSS) …

heart transplant
heart disease
heart transplantation
coagulopathy
lupus
  • 0 views
  • 04 Oct, 2022
  • 12 locations
GLP-1 and Hyperoxia for Organ Protection in Heart Surgery (GLORIOUS)

Patients undergoing open heart surgery are at risk of suffering damage to the heart, brain and kidneys. This study is designed as a 2-by-2 randomized clinical trial with the purpose of investigating the organ protective effects of the glucagon-like-peptide-1 (GLP-1) agonist Exenatide versus placebo and restrictive versus liberal oxygenation during …

glucagon
heart disease
ischemic heart disease
bypass graft
heart surgery
  • 40 views
  • 27 Jan, 2022
  • 1 location
Carpal Tunnel Syndrome and Amyloidosis (AMICAR)

amyloid.

carpal tunnel release
amyloid deposition
amyloid
  • 13 views
  • 25 Feb, 2022
  • 1 location
Ixazomib Maintenance Study in Patients With AL Amyloidosis

prevent or delay relapse of AL Amyloidosis.

vasectomy
leukemia
congo red
platelet count
nervous
  • 140 views
  • 26 Mar, 2022
  • 8 locations
Daratumumab and Pomalidomide in Previously Treated Patients With AL Amyloidosis (DarPAL)

This study aims at establishing a new powerful combination of daratumumab and pomalidomide as rescue treatment for patients with R/R AL amyloidosis.

dexamethasone
alkylating agent
daratumumab
bone marrow procedure
  • 0 views
  • 04 Oct, 2022
  • 2 locations
Novel Imaging Tools in Newly-diagnosed Patients With Cardiac AL Amyloidosis

This will be a systematic, combined, prospective assessment of the novel echographic, CMR, and PET imaging tools in newly-diagnosed patients with cardiac AL amyloidosis at baseline and after

renal function
nt-probnp
MRI
blood disorder
chemotherapy regimen
  • 5 views
  • 17 May, 2022
  • 1 location
Isatuximab as Upfront Therapy for the Treatment of High Risk AL Amyloidosis

This phase I trial studies the side effects of isatuximab and to see how well it works in treating patients with high risk immunoglobulin light chain amyloidosis (AL amyloidosis). Isatuximab is

monoclonal protein
congo red
bortezomib
platelet count
immunoglobulin
  • 0 views
  • 16 May, 2022
  • 1 location
Comparison of BTD and BCD Based Regimens in the Treatment of AL Amyloidosis

Research Objective:At present, there is no standard therapeutic regimen for monoclonal immunoglobulin light chain (AL) amyloidosis in the world. To compare the efficacy and safety of the

electrophoresis
bortezomib
thalidomide
immunoglobulin
cyclophosphamide
  • 0 views
  • 26 Jan, 2021
  • 1 location
Amyloidosis TTR Flow Reserve Evaluation (AMYTRE)

Anginal symptoms and signs of ischemia have been reported in some patients with cardiac amyloidosis (TTR) without obstructive epicardial coronary artery disease (CAD). It was found that

  • 0 views
  • 07 Jul, 2022
  • 1 location
A Phase 2 Study of Belantamab Mafodotin in Patients With Relapsed or Refractory AL Amyloidosis (EMN27)

This is an open-label, multicenter, Phase 2 study in subjects with previously treated patients with light chain (AL) amyloidosis in need for therapy. Approximately 35 subjects will

  • 0 views
  • 15 Oct, 2022
  • 1 location