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Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (51) clinical trials

Thalidomide/Dexamethasone Treatment And PET Evaluation In Organ Involvemenet of Cardiac Amyloidosis

Considering that dismal prognosis of amyloidosis is attributable to organ dysfunction, primary aim of amyloidosis treatment should be an organ reversal. However, due to various reasons, not much is known about organ reversal in amyloidosis. Almost all of the clinical trials evaluated hematologic response in amyloidosis. Meanwhile, besides autologous stem ...


Natural History Pathogenesis and Outcome of Autoinflammatory Diseases (NOMID/CAPS DIRA CANDLE SAVI NLRC4-MAS Still'S-like Diseases and Other Undifferentiated Autoinflammatory Diseases)

Autoinflammatory diseases are a group of immune dysregulatory diseases that are characterized by recurrent episodes of systemic inflammation as well as organ-specific inflammation that can involve the skin, eyes, joints, bones, muscles, lungs, serosal surfaces, inner ear, brain, and other organs. The prominent role of IL-1 in the pathogenesis of ...

Phase N/A

Carpal Tunnel/Amyloidosis Blood Sample Study

The investigators propose to assess a high risk population of patients, those with carpal tunnel syndrome, and systematically assess them for Amyloid Light-chain (AL) amyloidosis and Transthyretin-Related Amyloidosis (ATTR) with simple laboratory blood tests. The combination of serum immunofixation electrophoresis together with serum free light chain (FLC) assay approaches 100% ...

Phase N/A

A Diagnostic Screening Trial Seeking AL Amyloidosis Very Early

In this trial up to 200 patients with either light chain (LC) monoclonal gammopathy of undetermined significance (MGUS) or LC smoldering multiple myeloma (SMM) with a :: LC ratio < 0.26 and whose minus LC difference (dFLC) is greater than 23 mg/L will be recruited. Heavy chain type will not ...

Phase N/A

Efficacy of 308-nm Excimer Laser for Primary Localized Cutaneous Amyloidosis Treatment in Asians

Efficacy of 308-nm excimer laser for primary localized cutaneous amyloidosis treatment in Asians, pilot study.

Phase N/A

Assessment of Minimal Residual Disease (MRD) After Antineoplastic Treatment in Patients With AL Amyloidosis

In this study, the investigators seek to evaluate bone marrow and blood samples and treatment responses to see if Minimal Residual Disease (MRD) (as described below), can be used as a predictive method of response to treatment in amyloidosis. Minimal residual disease (MRD) is a concept that has gained significant ...

Phase N/A

Early Diagnosis of TTR Amyloidosis by Use of Molecular Biology

Study of the TTR gene by complete sequencing; search for amyloidogenic mutations of the TTR gene (according to the site http: // amyloidosismutations.com / mut-attr.php) in the laboratory of molecular biology of the CHU BICTRE (APHP) managed by Pr Anne Mantel. Preselection of the cases to be tested among the ...

Phase N/A

Efficacy and Safety of Ojeok-san on Korean Patients With Cold Hypersensitivity in the Hands and Feet

The Purpose of this trial is to investigate the efficacy and safety of Ojeok-san(OJS) on Korean Patients With Cold Hypersensitivity in the Hands


Assessment of Cardiac Fixation During PET Using a New Drug Within Amyloid Cardiac Injuries.

Hypothesis had been performed that PET with 18F-Flutemetamol (Vizamyl) could lead an early diagnostic. Indeed, this tracer had been recently used to highlight inter-cerebral beta-amyloid plaques on patients with Alzheimer Disease. Because this labelling is performed on amyloid deposits, this tracer would lead to view and to quantify amyloid deposits ...

Phase N/A

Transthyretin Cardiac Amyloidosis in HFpEF

Residents of Southeast Minnesota over 60 years of age with an inpatient or outpatient diagnosis of heart failure (HF) will be consecutively identified in real-time using a natural language processing (NLP) search engine, their HF diagnosis validated, and those with a recent ( 12 months) echocardiogram documenting a preserved EF( ...

Phase N/A