Amyloidosis Clinical Trials

A listing of Amyloidosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 246 clinical trials
A Direct Comparative Study of Tau Tracer in Patients With Alzheimer's Disease (HTH)

In this study, a total of 60 AD patients with Aβ deposition will beenrolled.Qualified subjects will complete PET imaging scan of Tau imaging agent inXuanwuHospital, and each subject will receive three of the following five imaging agents: PI-2620, APN1607, AV1451, RO948 or GTP1.The imaging time interval between the two tracers …

amyloid
mini-mental state examination
florbetapir
cognitive assessment
amnesia
  • 0 views
  • 05 May, 2022
  • 1 location
APOE in the Predisposition to, Protection From, and Prevention of Alzheimer's Disease

The purpose of this study is to track changes in the brain related to Alzheimer's disease. The results from this study will be used to develop new approaches to prevent or delay the onset of memory and thinking problems associated with Alzheimer's.

alzheimer's disease
amyloid
Accepts healthy volunteers
  • 0 views
  • 24 Jan, 2022
  • 1 location
Brain Iron Toxicity and Neurodegeneration - An Ultrahigh Field (7T) MRI Study (BITaN)

A longitudinal observational neuroimaging study of individuals with Early Onset Alzheimer's disease during the prodromal phase, and matched control group - Ultrahigh Field MRI study at 7T

  • 0 views
  • 19 Oct, 2022
  • 1 location
Depression and Driving (D&D)

This project will assess how depression, preclinical AD, and antidepressants affect driving behavior in cognitively normal older adults (65 years).

antidepressants
depressed mood
  • 0 views
  • 04 Oct, 2022
  • 1 location
Tau PET in Imaging and Cognition: Healthy Adults From 55-90

The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic resonance imaging (fMRI) neural activation patterns, and other cognitive …

cognitive impairment
mental deterioration
amyloidosis
positron emission tomography
amyloid
  • 61 views
  • 24 Mar, 2022
  • 1 location
F 18 T807 Tau PET Imaging in Dominantly Inherited Alzheimer's Network (IND 123119, Protocol D (AV ADAD)

The purpose of this research study is to evaluate a new radioactive compound used in positron emission tomography (PET) scans in identifying tau tangles (a certain protein that might be associated with Dominantly Inherited Alzheimer's Disease) in the brain, and if the amount of tau tangles in the brain has …

positron emission tomography
dementia
alzheimer's disease
mild dementia
  • 5 views
  • 10 Oct, 2022
  • 1 location
Identification of Proteostasis-related Biomarkers in Alzheimer´s Dementia

At the time of biomarker-substantiated diagnosis for a given AD patient it remains unclear to what extent the disease will devastate cognitive abilities within the next years. This is not only unsatisfying for the patient and the attending physician but also a major problem in the context of clinical trials …

alzheimer's disease
neuropsychological test
cognitive assessment
dementia
  • 0 views
  • 14 Mar, 2022
  • 1 location
ROSE-Longitudinal Assessment With Neuroimaging

The investigators will perform follow-up on 250 of 500 cases recruited into the ROSE study of cases with deep and lobar intracerebral hemorrhage to perform advanced neuroimaging at 12-24 months post stroke, and evaluations of motor and cognitive function at baseline, 6 months after baseline, and 12 months after baseline …

  • 0 views
  • 28 Oct, 2021
  • 7 locations
Diagnosis of Alzheimer's Disease Using Event Related Potentials

This study evaluates the use of an EEG device using Event Related Potentials to help diagnose Alzheimer's Disease in the outpatient clinical setting.

memory impairment
memory loss
alzheimer's disease
  • 5 views
  • 07 Oct, 2022
  • 1 location
Biomarkers in Polyradiculoneuropathies (BIP)

The nodes of Ranvier contain ion channels that enable the rapid propagation of the nerve impulse. Cell adhesion molecules and glycolipids play an important role in the formation of the nodes of Ranvier. Antibodies against glycolipids are detected in half of patients with Guillain-Barr syndrome, an acute inflammatory neuropathy affecting …

cell adhesion molecules
adhesion
polyradiculoneuropathy
neuromuscular diseases
inflammatory neuropathy
  • 59 views
  • 24 Feb, 2022
  • 1 location