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Chronic Pain Clinical Trials

A listing of Chronic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (6) clinical trials

PROSTVAC in Combination With Nivolumab in Men With Prostate Cancer

Background Immune checkpoint inhibitors interfere with the immune system s autoregulatory mechanisms, allowing for a potentially expanded and prolonged T-cell response with the possibility of greater antitumor effects. Nivolumab is a fully human IgG4 monoclonal antibody that targets the PD-1 protein. Specifically, the antibody binds to the PD-1 receptor and ...


Biodistribution and Dosimetry of Ga-68 P16-093 in Prostate Cancer With Biochemical Recurrence

Initial performance of Ga-68-P16-093 in prostate cancer patients including dosimetry and preliminary efficacy evaluation in BCR patients, and correlation of Ga-68-P16-093 uptake with tissue histopathology in intermediate to high risk primary prostate cancer patients.


Sustained Release Lidocaine for Treatment of Scrotal Pain

The purpose of this study is to find out if a new polymeric, water-free formulation of lidocaine is safe and can provide effective, long-lasting pain relief in chronic scrotal pain (CSCP) patients. This new formulation ST-CP is injected into the spermatic cord of patients in a very comparable way that ...


Combination of Nivolumab Immunotherapy With Radiation Therapy and Androgen Deprivation Therapy

The purpose of this study is to test the safety, tolerability, and effectiveness of the investigational drug nivolumab (Opdivo) in combination with high dose radiation. Investigators also want to see if these study drugs help to delay the progression of prostate cancer.


Use of Autologous Adipose-Derived Stem/Stromal Cells (AD-cSVF) in Symptomatic Benign Prostate Hypertrophy

Benign prostate hypertrophy (BPH) and inflammation are common non-cancerous enlargement of the prostate, which result in urinary interference and incomplete drainage of the bladder. Compression of the urethra is common cause of such resistance of full draining, and may over time result in progressive hypertrophy, instability, urgency, nocturia and weakness ...


Effects of N-Methyl-D-Aspartate (NMDA)-Receptor Antagonism on Hyperalgesia Opioid Use and Pain After Radical Prostatectomy

The immediate postoperative period is associated with spontaneous pain and hyperalgesia, i.e., increased pain response (both intensity and duration) to normally painful stimuli following tissue injury or damage. The development and maintenance of secondary hyperalgesia depend on complex plastic changes in spinal cord dorsal horn cells after peripheral injury or ...