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Chronic Pain Clinical Trials

A listing of Chronic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (397) clinical trials

Lessons in Affect Regulation to Keep Stress and Pain UndeR Control (LARKSPUR R34)

Chronic pain affects millions of Americans but integrative as well as conventional treatments fall short in terms of alleviating this pain. The investigators are testing a tailored online positive affect skills intervention through a high-quality, randomized controlled trial for people with chronic musculoskeletal pain. The proposed work holds promise as ...

Phase N/A

Combining Mechanisms for Better Outcomes (COMBO)

To evaluate the effectiveness of Spinal Cord Stimulation (SCS) with multiple modalities as compared to conventional SCS in patients with chronic pain when using the Boston Scientific Spectra WaveWriter SCS System.

Phase N/A

The Effect of Pain Education on Multidisciplinary Healthcare Students' Understanding of Chronic Pain

In 2011 Briggs et al described pain education at undergraduate level for healthcare professionals as 'woefully inadequate'. Pain Neurophysiology Education (PNE) can improve undergraduates' pain understanding/management, however previous RCTs used single discipline groups and immediate follow-up. Investigation of the effectiveness of this education on students across the multi-professional team with ...

Phase N/A

Randomized Controlled Trial for Treatment of Pain and Assessment of Wound Healing in Chronic Venous Leg Ulcers Using Near Infrared Laser Therapy

The K-Laser Cube is an FDA cleared light-emitting device for applying infrared to provide topical heating for the purpose of elevating tissue temperature for temporary relief of minor muscle and joint pain, muscle spasm, pain and stiffness associated with arthritis and promoting relaxation of the muscle tissue and to temporarily ...

Phase N/A

Intra-operative Lidocaine Infusion in Preventing CPSP Post VATs

It is not surprising that complications related to surgical procedures occur. Chronic Post Surgical Pain (CPSP) is considered one of the more common surgical complications, despite all the advances in understanding acute pain and the development of new modalities for pain management 1. Chronic Post Surgical Pain was defined by ...


Reducing Opioid Use for Chronic Pain Patients Following Surgery

The proposed research program encompasses several study designs to evaluate the effectiveness and potential implementation of the TPSP across Ontario. The investigators will use three approaches to create a comprehensive evidence-base that can be used to guide future policy and programs related to the management of surgical patients with complex ...

Phase N/A

Omnitram Safety and Efficacy in the Treatment of Diabetic Neuropathy

A multi-centered, randomized, double-blind, placebo-controlled, two-period cross-over study to compare the safety and efficacy of Omnitram (30 mg to 120 mg daily) and placebo in patients with painful diabetic polyneuropathy. For subjects receiving treatment for neuropathic pain prior to study enrollment, their treatment will be tapered and stopped at least ...


Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain

The long-term objective is to reduce overall low back pain (LBP) burden by testing scalable, first-line, non-pharmacologic strategies that address the biopsychosocial aspects of acute/sub-acute LBP and prevent transition to chronic back pain. The US is in the midst of an unprecedented pain management crisis. LBP is the most common ...


Integral Versus Local Movement Therapy Approach in Patients With Idiopathic Chronic Low Back Pain

Literature suggests several different methods for coping with CLBP. Supervised exercise therapies are among the most commonly advocated treatments for nonspecific CLBP. However, findings from a systematic reviews concluded the most effective model of exercise therapy remain uncertain. Although several supervised randomized controlled trails, focusing on different approaches for managing ...

Phase N/A

Cooperative Pain Education and Self-management

Cognitive behavioral therapy (CBT) for chronic pain is a commonly used evidence-based self-management intervention. Though effective, CBT requires that patients attend multiple in-person visits and that highly trained staff be available to provide care. For these reasons CBT is resource intensive, often inaccessible to Veterans, and delivered unevenly across patients ...

Phase N/A