Chronic Pain Clinical Trials

A listing of Chronic Pain medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 252 clinical trials
Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial (COPE)

Psychological factors such as stress, distress, anxiety, depression, and poor coping strategies may be associated with ongoing pain following injuries such as fractures. To study this relationship, patients will undergo cognitive behavioural therapy (CBT) which is designed to modify such thoughts with the goal of reducing ongoing pain and improving …

anxiety
behavior therapy
  • 0 views
  • 04 Apr, 2023
  • 5 locations
SMART Stepped Care Management for Low Back Pain in the Military Health System (SMART LBP)

This study will be sequential, randomization trial where patients with chronic low back pain are initially randomized to receive 1 of 2 treatments (physical therapy OR Move 2 Health). This will be Phase I of the study intervention. Patients who do not respond to treatment after 6 weeks will undergo …

lumbar disc herniation
back pain
low back pain
pain relieving
analgesia
  • 178 views
  • 04 Oct, 2022
  • 4 locations
A Depression and Opioid Pragmatic Trial in Pharmacogenetics (DCRI Coordinating Center) (ADOPT PGx)

are the Acute Pain Trial, the Chronic Pain Trial, and the Depression Trial. Participants can enroll in only one of the three trials. Acute Pain Trial: A prospective, multicenter, two arm

pain relieving
depressive symptoms
depressed mood
arthritis
tramadol
  • 299 views
  • 04 Oct, 2022
  • 10 locations
A Randomized Clinical Trial to Evaluate Non-Pharmacologic and Pharmacologic Approaches for Reducing Pain and Opioid Use Among Patients Treated With Maintenance Hemodialysis (HOPE)

HOPE is a randomized clinical trial that will evaluate approaches to reducing pain and opioid use among patients with chronic pain who are receiving maintenance hemodialysis for end-stage renal

chronic pain
opioid
opioid agonist
buprenorphine
motivational interviewing
  • 31 views
  • 21 Oct, 2022
  • 15 locations
Efficacy and Safety of MEDI7352 in Subjects With Painful Diabetic Neuropathy

This is a study investigating the effect of MEDI7352 on chronic pain in patients with painful diabetic neuropathy. The study incudes a screening period of up to 45 days and a 12-week

analgesics
chronic pain
diabetic neuropathy
body mass index
administered intravenously
  • 172 views
  • 04 Apr, 2023
  • 23 locations
Syndrome Fibromyalgique en France : Place de l'évaluation et de la Prise en Charge Des Troubles du Sommeil (FIBOBS)

The FIBOBS study is a multi-centered, observational, prospective study carried out within specialized chronic pain structures (CPS) in France. It will estimate the prevalence of sleep disorders

chronic pain
  • 17 views
  • 23 Oct, 2022
  • 41 locations
Spinal Manipulation and Patient Self-Management for Preventing Acute to Chronic Back Pain (PACBACK)

LBP and prevent transition to chronic back pain. The US is in the midst of an unprecedented pain management crisis. LBP is the most common chronic pain condition in adults and the leading cause

back pain
analgesics
manipulation
pain relieving
manipulative therapy
  • 665 views
  • 04 Apr, 2023
  • 2 locations
Direct Patient Feedback on Postoperative Pain (DPF)

persistent post-surgical pain. Severity and duration of pain after surgery appear to have a role in this process but the transition from acute postoperative pain to chronic pain is only partially understood

  • 0 views
  • 07 Apr, 2023
  • 1 location
Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response (SCEPTER)

VETERANS ONLY. Chronic low back pain (cLBP) is common. Most Americans will have at least one episode of low back pain in their lifetimes. Approximately 50% of all US Veterans have chronic pain

  • 0 views
  • 04 Oct, 2022
  • 4 locations
Quadratus Lumborum Block vs Erector Spinal Block for Post Abdomen Surgery Analgesia

The Erector Spinal Block (ESP) is based on the deposition of the local anesthetic in the inter-fascial space between the dorsal extensor muscle and the intercostal muscles at the height of the transverse processes. The scope of the blockade covers the dorsal and ventral branches of the thoracic spinal nerves, …

ropivacaine
pain relieving
analgesia
  • 0 views
  • 04 Oct, 2022
  • 1 location