Irritable Bowel Syndrome (IBS- Pediatric) Clinical Trials

A listing of Irritable Bowel Syndrome (IBS- Pediatric) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 46 clinical trials
ConfocAl endomicroSCopy bAsed Diet Trial in IBS

After a thorough baseline evaluation, IBS patients will be exposed to nutrients while undergoing confocal laser endomicroscopy (CLE). Patients presenting an acute mucosal reaction upon nutrient exposure will be instructed to exclude their respective trigger nutrient or a nutrient without mucosal reaction (=sham diet) from their diet for 4 weeks …

Accepts healthy volunteers
  • 0 views
  • 18 Nov, 2021
  • 1 location
Effects of Lactose-free Dairy Products on Athletes With Irritable Bowel Syndrome

Irritable Bowel Syndrome (IBS) is a gastrointestinal disorder defined by recurrent abdominal pain, bloating, abdominal distention and altered bowel habits. IBS is common among athletes and can impair performance. IBS was found to be prevalent in 9.8% (n=430) of endurance athletes. The condition is associated with significantly reduced quality of …

gastrointestinal symptoms
gastrointestinal disorder
bloating
acidophilus
calcium
  • 3 views
  • 22 Aug, 2021
  • 1 location
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.

Irritable bowel syndrome (IBS) is a frequently encountered disorder. According to the Rome IV criteria, it is characterized by abdominal pain associated with a change in stool frequency or con-sistency, or with symptomatic improvement by defecation (Mearin 2016). Associated symptoms, such as bloating and flatulence, are frequently reported. The underlying …

diarrhea
abdominal pain
bloating
fodmap diet
polyols
  • 0 views
  • 04 Oct, 2022
  • 1 location
The Efficacy of Sodium Butyrate and Probiotics in Patients With Irritable Bowel Syndrome

According to current IBS management guidelines, probiotic administration reduces IBS-associated symptoms and improves the quality of life. The purpose of this study is to assess the effects of the combined formulation comprising microencapsulated sodium butyrate and a probiotic mixture of two Lactobacillus strains (L. rhamnosus and L. acidophilus) and three …

abdominal symptom
abdominal pain
nortriptyline
constipation
longum
  • 0 views
  • 29 Aug, 2021
  • 1 location
Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

The primary objectives of this study are to explore the therapeutic effect of eluxadoline in treating irritable bowel syndrome with diarrhea (IBS-D) in pediatric participants 6-17 years of age, to evaluate the pharmacokinetics of eluxadoline in pediatric participants with IBS-D, and to evaluate the safety and tolerability of eluxadoline in …

diarrhea
abdominal pain
crohn's disease
ulcerative colitis
eluxadoline
  • 790 views
  • 07 Oct, 2022
  • 29 locations
A 52-Week, Multicenter, Randomized, Double-blind, Placebo and Active-Controlled, Operationally Seamless Phase 2b/3, Parallel-group Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Crohn's Disease (INTREPID Lead-In) (INTREPID)

This study seeks to evaluate the safety and efficacy of brazikumab versus placebo (Stage I) and versus an active comparator (Stage 2) in participants with moderately to severely active CD and will include assessments of clinical response as demonstrated by improvement of symptoms and colonic mucosal appearance as observed on …

mercaptopurine
immunomodulators
azathioprine
conventional treatment
aminosalicylate
  • 550 views
  • 20 Oct, 2022
  • 78 locations
A 54-Week, Multicenter, Randomized, Double-blind, Placebo Controlled, Parallel-group Phase 2 Study to Assess the Efficacy and Safety of Brazikumab in Participants With Moderately to Severely Active Ulcerative Colitis (Expedition Lead-in) (Expedition)

The present study (D5272C00001/Legacy #3151-201-008) aims to evaluate the efficacy and safety of brazikumab in patients with moderately to severely active UC and will include assessments of clinical responses as demonstrated by improvement of symptoms and of colonic mucosal appearance as observed on endoscopy.

rectal bleeding
immunomodulators
vedolizumab
aminosalicylates
hysterectomy
  • 392 views
  • 28 Oct, 2022
  • 74 locations
Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Aim More insight in pathogenesis of IBS and IBD. Samples are collected in context of an European research project.

ulcerative colitis
bowel dysfunction
crohn's disease
colitis
  • 39 views
  • 21 Jan, 2021
Ethosuximide and Pentoxifylline in the Treatment of Abdominal Pain Related to Irritable Bowel Syndrome

Ethosuximide and pentoxifylline in the treatment of abdominal pain related to irritable bowel syndrome

abdominal pain
mebeverine
  • 2 views
  • 23 Jan, 2021
  • 1 location
Effects of Low FODMAP Diet on Colonic Epithelial Physiology in Diarrhea-predominant Irritable Bowel Syndrome

This research is studying whether changing an individual's diet may have an impact as a treatment or outcome for Irritable Bowel Syndrome (IBS). This research will show if diet might play a role in triggering changes that may cause IBS. This study is being done to learn if a low …

diarrhea
fodmap diet
polyols
  • 10 views
  • 16 Jun, 2022
  • 1 location