Search Medical Condition
Please enter condition
Please choose location from dropdown
Clear Trial Filters

Psychosis Clinical Trials

A listing of Psychosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (780) clinical trials

tACS for Amyloid- Reduction in Alzheimer's Disease

Alzheimer's Disease (AD) is characterized by amyloid- (A) plaque buildup and phosphorylated tau (p-tau) in the brain, as well as widespread neurodegeneration. There is no current treatments that alter disease progression. Investigators will recruit 20 individuals with AD with evidence of amyloid placques in the brain through Positron Emission Tomography ...

Phase N/A

Feasibility and Effects of Valaciclovir Treatment in Persons With Early Alzheimer's Disease

This study investigates the effects of valaciclovir treatment to individuals with Alzheimer's disease (AD) or Mild Cognitive Impairment of Alzheimer's Disease Type. It is an open pilot trial where 36 participants will receive 4 weeks of oral valaciclovir treatment. To find 36 persons fulfilling inclusion criteria, up to 120 persons ...

Phase

Effect of Low Dose Radiotherapy on Brain Amyloidosis in the Treatment of Alzheimer's Disease

Alzheimer's Disease (AD) is the most frequent neurodegenerative disease associated with dementia, with a constantly increasing prevalence associated with an aging population. Amyloid deposition is considered the first molecular event occurring in AD: as already showed in an animal model, a low-dose radiotherapy (RT) course is capable of reducing AD-associated ...

Phase N/A

CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)

Oral Abilify (aripiprazole) is effective in the treatment of patients with BD when prescribed as an acute anti-manic agent and for the maintenance treatment of bipolar disorder. Abilify Maintena is an intramuscular (IM) depot formulation of oral aripiprazole (Abilify). Abilify Maintena appears to be as effective as standard oral Abilify ...

Phase

Exercise and Markers of Medial Temporal Health in Youth At-risk for Psychosis

Accumulating evidence from the animal literature, healthy populations, and schizophrenia studies suggests that regular exercise positively affects integral functions such as neurogenesis, synaptic plasticity and cognition. Likewise, preliminary evidence suggests that aerobic activity has been associated with improved quality of life and a lower level of symptoms in patients with ...

Phase N/A

New Clinical Applications for Internet-based Cognitive Behavior Therapy for Insomnia and Depression

This study includes two sub-trials. Both are included in this singe registration since they have parallel inclusion of participants and have been approved by the Swedish ethics board together in one application. Trial 1 includes patients with both insomnia and major or minor depression. Participants are randomized to either a ...

Phase N/A

Selenium as Augmentation Treatment for Sertraline Resistant Major Depression

This research aims to verify in a pilot study the effect of selenium as an augmentation treatment for sertraline-resistant major depression and, as secondary endpoints, if the levels of selenium in patients with depressive episodes are different from individuals without depression. Thus, this clinical trial was intended to be a ...

Phase N/A

Mechanism of Antidepressant-Related Dysfunctional Arousal in High-Risk Youth

The primary goals of this proposal are to investigate the etiological mechanisms associated with antidepressant-related dysfunctional emotional arousal and to characterize baseline neurobiological risk factors that predict the development of dysfunctional emotional arousal in treatment seeking youth with a family history of BD. Antidepressants have moderate benefit for treating mood ...

Phase N/A

Salsalate in Patients Mild to Moderate Alzheimer's Disease

This is a Phase 1b, 12-month, randomized, double-blind, placebo-controlled study of the safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary efficacy of salsalate in patients with mild to moderate AD. Approximately 40 subjects will be randomized 1:1 to placebo or active. All study drugs will be administered orally bid [two placebo tablets ...

Phase

Infiltrations of OnaBotulinum Toxin A in Resistant Depression: Comparison of Two Facial Injection Sites.

Three randomized, double-blind, placebo-controlled studies have shown that a single injection of OnaBotulinum Toxin A (OnaA) into the corrugator and procerus (frowning muscles) allows for a significant decrease in patients with a depressive episode characterized resistant. However, the effectiveness of this method of treating depression can not currently be considered ...

Phase N/A