Psychosis Clinical Trials

A listing of Psychosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 134 clinical trials
An Open-Label Trial of Repetitive Transcranial Magnetic Stimulation for Opioid Use Disorder

The purpose of this study is to understand the role of repetitive Transcranial Magnetic Stimulation (rTMS) in reducing opioid and other substance use and craving and improving thinking skills.

buprenorphine
opioid
urine drug screen
substance use
structured clinical interview
  • 0 views
  • 04 Oct, 2022
  • 1 location
Passive Mobile Self-Tracking of Mental Health by Veterans With Serious Mental Illness

Serious mental illnesses require years of monitoring and adjustments in treatment. Stress, substance abuse or reduced medication adherence cause rapid worsening of symptoms, with consequences that include job loss, homelessness, suicide, incarceration, and hospitalization. Treatment visits can be infrequent. Illness exacerbations usually occur with no clinician awareness, leaving little opportunity …

psychiatric symptoms
schizophrenia
suicide
bipolar disorder
psychiatric hospitalization
  • 23 views
  • 24 Oct, 2022
  • 1 location
Adapting and Examining Collaborative Decision Skills Training Among Veterans With Serious Mental Illness (CDST)

Recovery-oriented care is an imperative for the VA, particularly in mental health programming for Veterans with serious mental illness (SMI). Collaborative decision-making (CDM) is a recovery-oriented approach to treatment decision-making that assigns equal participation and obligation to patients and providers across all aspects of decision-making, thereby empowering patients and facilitating …

major depressive disorder
delusional disorder
psychosocial rehabilitation
schizophrenia
schizoaffective disorder
  • 0 views
  • 04 Oct, 2022
  • 1 location
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease Dementia (ADEPT-1) (ADEPT-1)

This is a Phase 3, 38-week, randomized, double-blind, placebo-controlled, multicenter, outpatient study in subjects with psychosis associated with Alzheimer's Disease dementia. The

  • 0 views
  • 28 Mar, 2023
The Role of Inflammation in Brain and Cognitive Function in Mental Disorders (IRIS)

schizophrenia, or whether this is a secondary phenomenon of no pathophysiological significance. The investigators therefore plan to test the effect of a monoclonal antibody (natalizumab) on psychotic symptoms

psychosis
Accepts healthy volunteers
psychotic symptoms
  • 0 views
  • 14 Oct, 2022
  • 1 location
An Open-label Extension Study to Assess the Long-term Safety, Tolerability, and Efficacy of KarXT in Subjects With DSM-5 Schizophrenia

This is a Phase 3, multicenter, 53-week, outpatient, open-label extension (OLE) study to evaluate the long-term safety, tolerability, and efficacy of KarXT in subjects with Diagnostic and Statistical Manual-Fifth Edition (DSM-5) schizophrenia who previously completed the treatment period of one of the two Phase 3 double-blind studies, KAR-007 or KAR-009. …

  • 15 views
  • 22 Oct, 2022
  • 9 locations
Do Antipsychotic Agents Induce Supersensitivity in Humans: A Combined PET/MRI Study in Patients With Schizophrenia

dopamine receptors is altered, which are associated with the onset of psychotic symptoms. For this purpose, a single PET/MR measurement will be performed in all participants. In total 140 volunteers

psychiatric disorder
antidepressants
aripiprazole
psychotic symptoms
benzodiazepines
  • 0 views
  • 04 Oct, 2022
  • 1 location
Cerebral Impact of Cognitive Remediation for People Suffering From Schizophrenia (IMPACTRCS)

Neurocognitive deficits are frequent with people suffering from schizophrenia. Unlike positive symptoms, cognitive deficits are not reduced with antipsychotic medication. They can be very disabling, especially for social and professional rehabilitation. Cognitive deficits can concern primary processes such as attention or more integrative processes. Social cognition is also massively altered. …

antipsychotics
cognitive deficits
psychosocial rehabilitation
cognitive remediation
cognitive symptoms
  • 0 views
  • 04 Oct, 2022
  • 1 location
Trial to Evaluate the Short-term Safety & Efficacy of Brexpiprazole Monotherapy in the Treatment of Adolescents With Schizophrenia

To determine the safety & efficacy of brexpiprazole monotherapy in the treatment of adolescents with schizophrenia.

brexpiprazole
aripiprazole
  • 60 views
  • 07 Oct, 2022
  • 1 location
Effects of Brain Stimulation on Cognition, Oscillations and GABA Levels in Schizophrenia

People with schizophrenia often have problems with attention, learning and memory and other cognitive abilities that interfere with their work and school performance. Unfortunately, even our best treatments often do not significantly reduce these cognitive problems. The current study investigates whether or not delivering a very small electrical current to …

antipsychotics
clozapine
Accepts healthy volunteers
transcranial direct current stimulation
schizoaffective disorder
  • 6 views
  • 04 Oct, 2022
  • 1 location