Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 338 clinical trials
SArcopenia, Mobility, PHYsical Activity and Post-operative Risk of Bladder Carcinoma in the Elderly (SAMPHYR)

Sarcopenia is associated with lower prognosis in solid tumors, but this has not been studied in bladder carcinoma requiring cystectomy. According to EWGSOP recommendations, the diagnosis of sarcopenia is based on walking speed, grip strength and muscle mass. These three elements can easily be measured (specially muscle mass measurement by …

radical cystectomy
malnutrition
bladder carcinoma
mass measurement
grip
  • 20 views
  • 30 Jan, 2022
  • 2 locations
Transurethral Modified En Bloc Resection For Large Bladder Tumours.

Modified en bloc resection is a hybrid technique involving piecemeal resection of the exophytic part of the bladder tumour, followed by en bloc resection of the tumour base. In this study, we shall investigate the efficacy of modified en bloc resection for patients with bladder tumours of ≥3cm in size.

  • 0 views
  • 15 Jul, 2022
  • 1 location
Comparison of Safety and Efficacy of Detaenial Sigmoid Neobladder and Ileal Neobladder

Bladder cancer is a common malignant tumor of the urinary system, radical resection plus urinary diversion is the first choice of treatment for muscle invasive bladder cancer. Urinary diversion of surgical options related to patient' survival and quality of life. In 1988, Hautmann firstly reported an orthotopic urinary diversion method: …

carcinoma in situ
cancer
bladder carcinoma
invasive bladder cancer
hydronephrosis
  • 0 views
  • 04 Oct, 2022
  • 1 location
Electrical Stimulation for Continence After Spinal Cord Injury

This study aims to improve continence and voiding of patients with spinal cord injury using electrical stimulation. The Finetech Vocare Bladder System is an implantable sacral nerve stimulator for improving bladder and bowel function in patients with spinal cord injury (SCI). It has been commercially available in Britain and other …

urodynamic studies
spinal cord
electrical stimulation
bladder contraction
incomplete spinal cord injury
  • 272 views
  • 09 May, 2022
  • 4 locations
Cognitive, Urinary, and Functional Trajectories of Older Women Using Pharmacologic Treatment Strategies for Urgency Incontinence (TRIUMPH)

The TRIUMPH study is a randomized, double-blinded, 3-arm, parallel-group trial designed to compare the effects of anticholinergic bladder therapy versus a) beta-3-adrenergic agonist bladder therapy and b) no bladder pharmacotherapy on cognitive, urinary, and other aging-related functional outcomes in ambulatory older women with urgency-predominant urinary incontinence and either normal or …

Accepts healthy volunteers
  • 0 views
  • 14 Oct, 2022
  • 2 locations
Treatment Of Metastatic Bladder Cancer at the Time Of Biochemical reLApse Following Radical Cystectomy (TOMBOLA)

Immunotherapy (checkpoint inhibitors) is approved as first and second line treatment to patients with metastatic bladder cancer. However, response rates are low and no biomarkers have yet shown strong predictive value for patient selection. Moreover, the term 'metastatic' is based on metastases visible on conventional CT scans and, thus, require …

radical cystectomy
metastasis
cancer
transitional cell carcinoma
metastatic bladder carcinoma
  • 0 views
  • 04 Oct, 2022
  • 5 locations
Phase II Study of Oral Metformin for Intravesical Treatment of Non-muscle-invasive Bladder Cancer (TROJAN)

A multi-center, open-label, phase II clinical study of metformin in up to evaluable 49 patients with low-grade NMIBC with the aim to determine the overall response to administration of oral metformin for 3 months in a marker tumour deliberately left following transurethral resection of multiple, papillary NMIBC tumours.

carcinoma in situ
cancer
bladder carcinoma
transurethral resection
transitional cell carcinoma
  • 1 views
  • 23 Feb, 2022
  • 1 location
Cabozantinib Plus Pembrolizumab as First-Line Therapy for Cisplatin-Ineligible Advanced Urothelial Carcinoma (PemCab)

This is an open label, non-randomized phase 2 study of the combination of pembrolizumab and cabozantinib to assess overall response rate (ORR), progression free survival at 6 months (PFS6), and overall survival (OS) in patients with metastatic urothelial carcinoma (UC) ineligible for cisplatin.

metastasis
transitional cell carcinoma
antineoplastic
metastatic urothelial carcinoma
advanced urothelial carcinoma
  • 22 views
  • 01 Jul, 2022
  • 2 locations
Avelumab and Radiation in Muscle-Invasive Bladder Cancer

This research study is studying the effects of adding a certain type of immunotherapy to standard bladder-directed radiation as a treatment for muscle-invasive urothelial carcinoma of the bladder. The drug in this study is: Avelumab (also known as BAVENCIO®)

cancer
transurethral resection
bladder carcinoma
transitional cell carcinoma
invasive bladder cancer
  • 0 views
  • 03 May, 2022
  • 2 locations
BTL Emsella Chair Versus Sham for the Treatment of Overactive Bladder (EmsellaOAB)

The purpose of this clinical trial is to compare the Emsella Chair therapy to Sham and to determine whether electromagnetic technology is effective in the treatment of overactive bladder (OAB). Currently there are no other studies utilizing the Emsella Chair for the treatment of OAB. Eligible subjects will receive 2 …

bladder symptoms
pelvic floor exercises
  • 2 views
  • 07 Oct, 2022
  • 1 location