Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 354 clinical trials
Investigation of Safety and Tolerability of Catumaxomab in Patients With NMIBC

The purpose of the study is to investigate the safety, tolerability, and preliminary efficacy of the monoclonal bispecific trifunctional antibody Catumaxomab in patients with non-muscle invasive bladder cancer (NMIBC).

neutrophil count
invasive bladder cancer
carcinoma
bladder tumor
intravesical administration
  • 1 views
  • 19 Apr, 2022
  • 1 location
Durvalumab and Vicineum in Subjects With High-Grade Non-Muscle-Invasive Bladder Cancer Previously Treated With Bacillus Calmette-Guerin (BCG)

Background Non-muscle-invasive bladder cancer is in the early stages. But it usually comes back after treatment. The drugs Vicineum and Durvalumab may help the immune system find and destroy cancer cells. Objective To test if the drugs Durvalumab and Vicineum together are safe and effective to treat people with bladder …

neutrophil count
invasive bladder cancer
bladder tumor
durvalumab
intravesical bcg
  • 257 views
  • 10 Aug, 2022
  • 1 location
Minimizing Pain During Office Intradetrussor Botox Injection

This will be a prospective double-blinded randomized controlled trial comparing two pre-treatment protocols for patients undergoing intradetrussor botox injections to determine if a buffered lidocaine solution offers superior pain control.

minimizing pain
botox
second line therapy
overactive bladder
  • 225 views
  • 14 Mar, 2022
  • 1 location
Red Clover Isoflavones in Postmenopausal Women With Urge Urinary Incontinence and Overactive Bladder

The purpose of this study is to investigate the effect of red clover isoflavones in postmenopausal women with and without urge urinary incontinence and overactive bladder

overactive bladder
incontinence
  • 0 views
  • 29 Aug, 2021
  • 1 location
A Sham-Controlled Study to Evaluate the Safety and Efficacy of a Smart, Self-Adjusting, Surgery-Free, Wearable Bladder Neuromodulation System for Overactive Bladder (REDUCEOAB)

This is a prospective, multi-center, sham-controlled study comparing the safety and effectiveness of the self-adjusting, surgery-free, wearable Active System to a Sham System on adult Subjects diagnosed with OAB.

micturition chart
bladder diary
neuromodulation
overactive bladder
  • 0 views
  • 07 Jun, 2022
  • 1 location
Effects of Transcutaneous Tibial Nerve Stimulation for Overactive Bladder Symptoms in Adults

For overactive bladder symptoms, there are numerous physiotherapy techniques have been found to be beneficial. Transcutaneous electrical stimulation of the tibial nerve is one of those treatment options, that is entirely a non-invasive, easy to apply, and cost-effective technique. Transcutaneous stimulation of the tibial nerve targets the sacral nerve plexus …

  • 0 views
  • 20 Jul, 2022
  • 3 locations
QUILT-3.032: A Multicenter Clinical Trial of Intravesical Bacillus Calmette-Guerin (BCG) in Combination With ALT-803 (N-803) in Patients With BCG Unresponsive High Grade Non-Muscle Invasive Bladder Cancer

This is a Phase II/III, open-label, single-arm, multicenter study of intravesical BCG plus N-803 or N-803 only in patients with BCG unresponsive high grade non-muscle invasive bladder cancer (NMIBC). All patients treated in the study will receive via a urinary catheter in the bladder, BCG plus N-803 or N-803 only …

invasive bladder cancer
bladder tumor
intravesical bcg
transurethral resection
transitional cell carcinoma
  • 290 views
  • 30 Jun, 2022
  • 15 locations
The Effectiveness and Safety of Neoadjuvant Intravesical Mitomycin-C Instillation

The aim of this study is to evaluate the effectiveness and safety of neoadjuvant intravesical mitomycin-C instillation in non-muscle invasive bladder cancer patients

invasive bladder cancer
bladder cancer
bladder tumor
cancer
mitomycin
  • 12 views
  • 23 Apr, 2022
  • 1 location
A Study to Test the Safety of Immunotherapy With Nivolumab Alone or With Ipilimumab Before Surgery for Bladder Cancer Patients Who Are Not Suitable for Chemotherapy

The purpose of this study is to test if immunotherapy with nivolumab alone or in combination with ipilimumab is safe and does not delay the planned bladder cancer surgery. The investigators want to see if treatment with these drugs prior to surgery may decrease the size of the bladder cancer …

neutrophil count
bladder tumor
surgery for bladder cancer
hydronephrosis
radical cystectomy
  • 9 views
  • 24 Mar, 2022
  • 7 locations
Electromotive Mitomycin-C (EMDA-MMC) in Preventing Recurrences in High-risk Non-muscle-invasive Bladder Cancer (FB10)

Disease recurrence and progression is a major issue in high risk non-muscle-invasive bladder cancer (NMIBC). The current study compares two adjuvant instillation therapies in the treatment of high risk NMIBC. After resection of the tumour(s), patients will receive either traditional regimen of Bacillus Calmette-Gurin (BCG) instillations or combination treatment consisting …

invasive bladder cancer
bladder tumor
mitomycin
bladder cancer
carcinoma
  • 18 views
  • 04 Feb, 2022
  • 7 locations