Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 354 clinical trials
Study of AZD5305 as Monotherapy and in Combination With Anti-cancer Agents in Patients With Advanced Solid Malignancies (PETRA)

This research is designed to determine if experimental treatment with PARP inhibitor, AZD5305, alone, or in combination with anti-cancer agents is safe, tolerable, and has anti-cancer activity in patients with advanced solid tumors.

carboplatin
parp inhibitor
chemotherapeutic agent
cancer
paclitaxel
  • 18 views
  • 27 Jul, 2022
  • 28 locations
The Use of cineMRI to Evaluate Botox in Patients With Medication Refractory Overactive Bladder

With the goal of providing improved treatment to patients with overactive bladder symptoms (OAB), the investigators seek to apply the new technology of time-resolved (cine) MRI combined with urodynamics (UDS) to understand the exact effect of intravesical botulinum toxin on bladder physiology. The investigators will specifically aim to assess the …

botox
botulinum toxin
incontinence
medical therapy
bladder symptoms
  • 35 views
  • 05 Mar, 2022
  • 1 location
Sham Controlled Trial of Rapid Induction Percutaneous Tibial Nerve Stimulation

The aim of this study is to determine the efficacy of an accelerated course for percutaneous tibial nerve stimulation (PTNS) induction to treat overactive bladder symptoms. The standard 12 weekly induction treatments may be a patient burden and a more rapid induction may speed up symptomatic improvement.

antimuscarinic
bladder symptoms
percutaneous tibial nerve stimulation
  • 26 views
  • 04 Mar, 2022
  • 1 location
Is 10 Injections of Bladder Botox Less Painful Than 20 Injections?

The purpose of this research study is to help determine if 10 injections of Botox ® 100 units is less painful than 20 injections of Botox ® 100 units based on effectiveness in reducing urge incontinence episodes. Study will also be assessed for the pain of procedure and adverse outcomes …

botox
onabotulinumtoxina
intermittent catheterization
incontinence
anticholinergic agents
  • 22 views
  • 10 Jul, 2022
  • 2 locations
TENS Used for Pain Management During Office Cystoscopy Botox Injections

The purpose of this study is to determine how Transcutaneous Electric Nerve Stimulation (TENS) units affects pain management during office cystoscopic Botox injections and patient satisfaction with the procedure .

botox
TENS
transcutaneous electrical nerve stimulation
  • 7 views
  • 23 Jul, 2022
  • 1 location
Intravesical Lactobacillus for Urinary Symptoms Among People With NLUTD Who Use Indwelling Catheters

The objectives of the proposed research among this population are: 1) to define clinically meaningful change (i.e. differentiating states of health and illness) with respect to urinary symptoms, urine inflammation, cultivable bacteria, and the urine ecosystem; and 2) to determine the optimal intravesical Lactobacillus RhamnosusGG (LGG®) dose to be used …

urinary symptoms
  • 0 views
  • 03 Jul, 2022
  • 1 location
Oxybutynin for Post-surgical Bladder Pain and Urgency

Bladder pain and urgency are common after bladder surgery. The objective is to determine if transdermal administration is superior to oral administration in alleviating pain and urgency.

oxybutynin
bladder surgery
  • 3 views
  • 25 Mar, 2022
  • 1 location
Reducing Anticholinergic Bladder Medication Use in Spinal Cord Injury With Home Neuromodulation (TTNS-RCT)

The purpose of this study is to determine the efficacy of home transcutaneous tibial nerve stimulation (TTNS) in spinal cord injury(SCI) and to determine the impact on quality of life using TTNS at home

spinal cord
anticholinergic agent
overactive bladder
  • 10 views
  • 07 Jun, 2022
  • 1 location
Overactive Bladder Telemedicine Non-inferiority Trial

In this study, the investigators aim to validate the telemedicine paradigm as a feasible alternative to traditional in-person clinic visits for the management of overactive bladder (OAB).

Accepts healthy volunteers
  • 0 views
  • 20 Nov, 2021
  • 1 location
Posterior Tibial Nerve Stimulation (PTNS) Plus Mirabegron to Treat Refractory OAB Symptoms (PTNS-M Study)

Abstract Introduction: Urgency Urinary Incontinence (UUI) is a common condition with a prevalence of 9-31% in women in the United States. Despite current treatments, a high number of women have symptoms refractory to first- and second-line treatment approaches. Aims: The primary aim of this randomized controlled trial is to compare …

mirabegron
Accepts healthy volunteers
percutaneous tibial nerve stimulation
incontinence
  • 0 views
  • 15 Dec, 2021
  • 1 location