Bladder Disorders Clinical Trials

A listing of Bladder Disorders medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 339 clinical trials
Robotic Sacrocolpopexy Versus High Uterosacral Ligament Suspension: A Randomized Trial

The purpose of this study is to compare the effectiveness of R-SCP versus HUSLS for treatment of pelvic organ prolapse.

prolapse repair
brimonidine tartrate ophthalmic solution
prolapse
sacrocolpopexy
  • 34 views
  • 16 Oct, 2022
  • 1 location
A Phase I Study of Bintrafusp Alfa (M7824) and NHS-IL12 (M9241) Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies

Background Genitourinary cancers are some of the most common types of cancer. They are lethal when they spread. The drug M7824 blocks the paths that cancer cells use to stop the immune system from fighting cancer. The drug M9241 triggers the immune system to fight cancer. Researchers want to learn …

ifosfamide
metastatic cancer
urine test
urine tests
bintrafusp alfa
  • 0 views
  • 21 Oct, 2022
  • 1 location
PhAse 1/2 StuDy of Modern ImmunotherApy in BCG-Unresponsive, BCG-RelaPsing, and High-Risk BCG-Naive Non-muscle Invasive UroThelial Carcinoma of the BLADDER (ADAPT)

Upon successful screening and registration, enrollment to durvalumab monotherapy (cohort 1) will begin. If DLT criteria outlined in the protocol are exceeded with durvalumab monotherapy (cohort 1), the study will close. Provided the safety of durvalumab monotherapy is established, enrollment to combination regimen cohorts will proceed. Cohorts will simultaneously enroll …

renal function
intravesical bcg therapy
transurethral resection
transitional cell carcinoma
neutrophil count
  • 47 views
  • 28 Oct, 2022
  • 7 locations
18Fluorine-Fluciclovine PET/CT for Staging Muscle Invasive Bladder Cancer Preceding Radical Cystectomy

This research study is studying a positron emission tomography (PET) agent called 18F-fluciclovine to evaluate how well 18F-fluciclovine-PET scans determine the extent of muscle invasive bladder cancer (as compared to regular CT and MRI imaging) and whether 18F-fluciclovine-PET scans can provide information about the pathologic grade of the tumor.

invasive bladder cancer
bladder cancer
cancer
metastasis
bladder tumor
  • 1 views
  • 18 Apr, 2022
  • 1 location
Neoadjuvant Toripalimab in Combination With Gemcitabine Therapy in Cisplatin Ineligible Local Advanved Bladder Cancer

This is a pre-surgical study involving subjects with muscle invasive bladder urothelial cancer, who are candidates for cisplatin ineligible neoadjuvant therapy. It is a one-arm phase II study in single center.

cancer
bladder cancer
transitional cell carcinoma
bladder tumor
carcinoma
  • 1 views
  • 03 Dec, 2021
  • 1 location
Comparison of Interfascial Injection Versus Subpectineal Injection on Ultrasound-guided Obturator Nerve Block

This study aimed to assess the effectiveness of the ultrasound-guided interfascial injection approach with the subpectineal injection technique for obturator nerve block in bladder cancers undergoing transurethral resection of bladder tumor (TURBT) under spinal anesthesia.

bladder tumor
transurethral bladder excision
transurethral resection
  • 0 views
  • 12 Oct, 2022
  • 1 location
Safety and Efficacy of Camrelizumab for High-risk NMIBC Failing BCG Treatment

This study will evaluate the safety of bladder instillation with Camrelizumab and compare to the efficacy of intravesical therapy with intravenous therapy using Camrelizumab in patients with high-risk non-muscle-invasive bladder cancer who failed BCG therapy.

bladder instillation
invasive bladder cancer
neutrophil count
bladder tumor
carcinoma
  • 0 views
  • 18 Oct, 2021
  • 3 locations
INvestigation of TENS Efficacy Versus Posterior Tibial Nerve Stimulation for Overactive Bladder (INTENSE)

The objective of this research is to perform a non-masked, non-inferiority randomized controlled trial to assess the quality of life (QOL) of women with idiopathic overactive bladder (OAB) before and after treatment with percutaneous tibial nerve stimulation (PTNS) or transcutaneous electrical nerve stimulation (TENS) of tibial nerve. The target population …

percutaneous tibial nerve stimulation
transcutaneous electrical nerve stimulation
incontinence
overactive bladder
TENS
  • 0 views
  • 04 Oct, 2022
  • 1 location
Pelvic Health Electrically Evoked Recording (PEER) 2 Study (PEER 2)

To collect physiological signals at several timepoints during the therapy evaluation period.

neuromodulation
incontinence
electrical stimulation
  • 0 views
  • 04 Oct, 2022
  • 6 locations
Recovery Support for Bladder Cancer Patients and Caregivers

For patients with certain types of bladder cancer, the removal of the bladder and the construction of an artificial bladder or reservoir are the only treatment options. Both before and after treatment, patients and caregivers face profound challenges preparing for surgery and planning for tasks during their recovery. To aid …

cancer
bladder cancer
bladder tumor
ileal conduit
urinary diversion
  • 0 views
  • 25 Feb, 2022
  • 2 locations